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Volumn 77, Issue 5, 2003, Pages 527-535

Differences between retinal and choroidal microvascular endothelial cells (MVECs) under normal and hypoxic conditions

Author keywords

Choroidea; Hypoxia; Microvascular endothelial cells; Neovascularization; Retina

Indexed keywords

ANGIOGENIC FACTOR; ANGIOPOIETIN; ANGIOTENSIN; ANGIOTENSIN I; CALNEXIN; COLONY STIMULATING FACTOR 1; CYTOKINE; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR RECEPTOR; MESSENGER RNA; RANTES; VASCULOTROPIN; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2;

EID: 0141534112     PISSN: 00144835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4835(03)00219-7     Document Type: Article
Times cited : (21)

References (50)
  • 2
    • 0035680855 scopus 로고    scopus 로고
    • Extracellular matrix-derived angiogenic factor(s) inhibit endothelial cell proliferation, enhance differentiation, and stimulate angiogenesis in vivo
    • Akhta N., Carlso S., Pesarini A., Ambulos N., Passaniti A. Extracellular matrix-derived angiogenic factor(s) inhibit endothelial cell proliferation, enhance differentiation, and stimulate angiogenesis in vivo. Endothelium. 8:2001;221-234.
    • (2001) Endothelium , vol.8 , pp. 221-234
    • Akhta, N.1    Carlso, S.2    Pesarini, A.3    Ambulos, N.4    Passaniti, A.5
  • 3
    • 0027213851 scopus 로고
    • Identification of differentially expressed mRNA species by an improved display technique (DDRT-PCR)
    • Bauer D., Muller H., Reich J., Riedel H., Ahrenkiel V., Warthoe P., Strauss M. Identification of differentially expressed mRNA species by an improved display technique (DDRT-PCR). Nucleic Acids Res. 21:1993;4272-4280.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 4272-4280
    • Bauer, D.1    Muller, H.2    Reich, J.3    Riedel, H.4    Ahrenkiel, V.5    Warthoe, P.6    Strauss, M.7
  • 4
    • 0030903210 scopus 로고    scopus 로고
    • Role of dissolved plasma oxygen in hyperoxia-induced contrast
    • Berkowitz B.A. Role of dissolved plasma oxygen in hyperoxia-induced contrast. Magn. Reson. Imaging. 15:1997;123-126.
    • (1997) Magn. Reson. Imaging , vol.15 , pp. 123-126
    • Berkowitz, B.A.1
  • 5
    • 0031267804 scopus 로고    scopus 로고
    • The influence of intraocular pressure and systemic oxygen tension on the intravascular pO2 of the pig retina as measured with phosphorescence imaging
    • Blumenroder S., Augustin A.J., Koch F.H. The influence of intraocular pressure and systemic oxygen tension on the intravascular pO2 of the pig retina as measured with phosphorescence imaging. Surv. Ophthalmol. 42 Suppl 1:1997;S118-S126.
    • (1997) Surv. Ophthalmol. , vol.42 , Issue.1 SUPPL.
    • Blumenroder, S.1    Augustin, A.J.2    Koch, F.H.3
  • 6
    • 0033895534 scopus 로고    scopus 로고
    • Retinal and choroidal neovascularization
    • Campochiaro P.A. Retinal and choroidal neovascularization. J. Cell Physiol. 184:2000;301-310.
    • (2000) J. Cell Physiol. , vol.184 , pp. 301-310
    • Campochiaro, P.A.1
  • 7
    • 0027163108 scopus 로고
    • A rapid and versatile method to synthesize internal standards for competitive PCR
    • Celi F.S., Zenilman M.E., Shuldiner A.R. A rapid and versatile method to synthesize internal standards for competitive PCR. Nucleic Acids Res. 21:1993;1047.
    • (1993) Nucleic Acids Res. , vol.21 , pp. 1047
    • Celi, F.S.1    Zenilman, M.E.2    Shuldiner, A.R.3
  • 8
    • 0033802949 scopus 로고    scopus 로고
    • Regulatory mechanisms in the retinal and choroidal circulation
    • Delaey C., van de Voorde J. Regulatory mechanisms in the retinal and choroidal circulation. Ophthalmic. Res. 32:2002;249-256.
    • (2002) Ophthalmic. Res. , vol.32 , pp. 249-256
    • Delaey, C.1    Van de Voorde, J.2
  • 9
    • 0035845561 scopus 로고    scopus 로고
    • Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias
    • Dias S., Hattori K., Heissig B., Zhu Z., Wu Y., Witte L., Hicklin D.J., Tateno M., Bohlen P., Moore M.A., Rafii S. Inhibition of both paracrine and autocrine VEGF/VEGFR-2 signaling pathways is essential to induce long-term remission of xenotransplanted human leukemias. Proc. Nat. Acad. Sci USA. 98:2001;10857-10862.
    • (2001) Proc. Nat. Acad. Sci USA , vol.98 , pp. 10857-10862
    • Dias, S.1    Hattori, K.2    Heissig, B.3    Zhu, Z.4    Wu, Y.5    Witte, L.6    Hicklin, D.J.7    Tateno, M.8    Bohlen, P.9    Moore, M.A.10    Rafii, S.11
  • 11
    • 0035052571 scopus 로고    scopus 로고
    • Oxygen modulates the release of urokinase and plasminogen activator inhibitor-1 by retinal pigment epithelial cells
    • Erichsen J.T., Jarvis-Evans J., Khaliq A., Boulton M. Oxygen modulates the release of urokinase and plasminogen activator inhibitor-1 by retinal pigment epithelial cells. Int. J. Biochem. Cell Biol. 33:2001;237-247.
    • (2001) Int. J. Biochem. Cell Biol. , vol.33 , pp. 237-247
    • Erichsen, J.T.1    Jarvis-Evans, J.2    Khaliq, A.3    Boulton, M.4
  • 12
    • 0033135876 scopus 로고    scopus 로고
    • Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development
    • Gale N.W., Yancopoulos G.D. Growth factors acting via endothelial cell-specific receptor tyrosine kinases: VEGFs, angiopoietins, and ephrins in vascular development. Genes Dev. 13:1999;1055-1066.
    • (1999) Genes Dev. , vol.13 , pp. 1055-1066
    • Gale, N.W.1    Yancopoulos, G.D.2
  • 13
    • 0030855630 scopus 로고    scopus 로고
    • Heterogeneity of endothelial cells. Specific markers
    • Garlanda C., Dejana E. Heterogeneity of endothelial cells. Specific markers. Arterioscler. Thromb. Vasc. Biol. 17:1997;1193-1202.
    • (1997) Arterioscler. Thromb. Vasc. Biol. , vol.17 , pp. 1193-1202
    • Garlanda, C.1    Dejana, E.2
  • 14
    • 0030751493 scopus 로고    scopus 로고
    • Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia
    • Gerber H.P., Condorelli F., Park J., Ferrara N. Differential transcriptional regulation of the two vascular endothelial growth factor receptor genes. Flt-1, but not Flk-1/KDR, is up-regulated by hypoxia. J. Biol. Chem. 272:1997;23659-23667.
    • (1997) J. Biol. Chem. , vol.272 , pp. 23659-23667
    • Gerber, H.P.1    Condorelli, F.2    Park, J.3    Ferrara, N.4
  • 15
    • 0034091204 scopus 로고    scopus 로고
    • Correlation of histologic 2-dimensional reconstruction and confocal scanning laser microscopic imaging of choroidal neovascularization in eyes with age-related maculopathy
    • Grossniklaus H.E., Cingle K.A., Yoon Y.D., Ketkar N., L'Hernault N., Brown S. Correlation of histologic 2-dimensional reconstruction and confocal scanning laser microscopic imaging of choroidal neovascularization in eyes with age-related maculopathy. Arch. Ophthalmol. 118:2000;625-629.
    • (2000) Arch. Ophthalmol. , vol.118 , pp. 625-629
    • Grossniklaus, H.E.1    Cingle, K.A.2    Yoon, Y.D.3    Ketkar, N.4    L'Hernault, N.5    Brown, S.6
  • 16
    • 0033525830 scopus 로고    scopus 로고
    • Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway
    • Kallio P.J., Wilson W.J., O'Brien S., Makino Y., Poellinger L. Regulation of the hypoxia-inducible transcription factor 1alpha by the ubiquitin-proteasome pathway. J. Biol. Chem. 274:1999;6519-6525.
    • (1999) J. Biol. Chem. , vol.274 , pp. 6519-6525
    • Kallio, P.J.1    Wilson, W.J.2    O'Brien, S.3    Makino, Y.4    Poellinger, L.5
  • 17
    • 0037044735 scopus 로고    scopus 로고
    • Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2
    • Kayyali U.S., Pennella C.M., Trujillo C., Villa O., Gaestel M., Hassoun P.M. Cytoskeletal changes in hypoxic pulmonary endothelial cells are dependent on MAPK-activated protein kinase MK2. J. Biol. Chem. 277:2002;42596-42602.
    • (2002) J. Biol. Chem. , vol.277 , pp. 42596-42602
    • Kayyali, U.S.1    Pennella, C.M.2    Trujillo, C.3    Villa, O.4    Gaestel, M.5    Hassoun, P.M.6
  • 20
    • 0022002617 scopus 로고
    • Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta
    • King G.L., Goodman A.D., Buzney S., Moses A., Kahn C.R. Receptors and growth-promoting effects of insulin and insulinlike growth factors on cells from bovine retinal capillaries and aorta. J. Clin. Invest. 75:1985;1028-1036.
    • (1985) J. Clin. Invest. , vol.75 , pp. 1028-1036
    • King, G.L.1    Goodman, A.D.2    Buzney, S.3    Moses, A.4    Kahn, C.R.5
  • 21
    • 0036137466 scopus 로고    scopus 로고
    • VEGF receptor signaling and endothelial function
    • Kliche S., Waltenberger J. VEGF receptor signaling and endothelial function. IUBMB Life. 52:2001;61-66.
    • (2001) IUBMB Life , vol.52 , pp. 61-66
    • Kliche, S.1    Waltenberger, J.2
  • 22
    • 0343580441 scopus 로고    scopus 로고
    • Calibration and storage of DNA competitors used for contamination-protected competitive PCR
    • Köhler T., Rost A.K., Remke H. Calibration and storage of DNA competitors used for contamination-protected competitive PCR. Biotechniques. 23:1997;722-726.
    • (1997) Biotechniques , vol.23 , pp. 722-726
    • Köhler, T.1    Rost, A.K.2    Remke, H.3
  • 23
    • 0033020625 scopus 로고    scopus 로고
    • Human endothelium as a source of multifunctional cytokines: Molecular regulation and possible role in human disease
    • Krishnaswamy G., Kelley J., Yerra L., Smith J.K., Chi D.S. Human endothelium as a source of multifunctional cytokines: molecular regulation and possible role in human disease. J. Interferon Cytokine Res. 19:1999;91-104.
    • (1999) J. Interferon Cytokine Res. , vol.19 , pp. 91-104
    • Krishnaswamy, G.1    Kelley, J.2    Yerra, L.3    Smith, J.K.4    Chi, D.S.5
  • 24
    • 0033774430 scopus 로고    scopus 로고
    • Microvascular endothelial cells (MVEC) differ in their basal and TNF-a regulated expression of adhesion molecules and cytokines
    • Lehmann I., Brylla E., Sittig D., Spanel-Borowski K., Aust G. Microvascular endothelial cells (MVEC) differ in their basal and TNF-a regulated expression of adhesion molecules and cytokines. J. Vasc. Res. 37:2000;408-416.
    • (2000) J. Vasc. Res. , vol.37 , pp. 408-416
    • Lehmann, I.1    Brylla, E.2    Sittig, D.3    Spanel-Borowski, K.4    Aust, G.5
  • 25
    • 0030249425 scopus 로고    scopus 로고
    • Cytokine regulation of GM-CSF and G-CSF secretion by human umbilical cord vein endothelial cells (HUVEC)
    • Lenhoff S., Olofsson T. Cytokine regulation of GM-CSF and G-CSF secretion by human umbilical cord vein endothelial cells (HUVEC). Cytokine. 8:1996;702-709.
    • (1996) Cytokine , vol.8 , pp. 702-709
    • Lenhoff, S.1    Olofsson, T.2
  • 26
    • 0034703039 scopus 로고    scopus 로고
    • Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization
    • Li B., Fuh G., Meng G., Xin X., Gerritsen M.E., Cunningham B., de Vos A.M. Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization. J. Biol. Chem. 275:2000;29823-29828.
    • (2000) J. Biol. Chem. , vol.275 , pp. 29823-29828
    • Li, B.1    Fuh, G.2    Meng, G.3    Xin, X.4    Gerritsen, M.E.5    Cunningham, B.6    De Vos, A.M.7
  • 27
    • 0032457434 scopus 로고    scopus 로고
    • Differential display. A general protocol
    • Liang P., Pardee A.B. Differential display. A general protocol. Mol. Biotechnol. 10:1998;261-267.
    • (1998) Mol. Biotechnol. , vol.10 , pp. 261-267
    • Liang, P.1    Pardee, A.B.2
  • 28
    • 0035476882 scopus 로고    scopus 로고
    • Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor
    • Lu D., Jimenez X., Zhang H., Wu Y., Bohlen P., Witte L., Zhu Z. Complete inhibition of vascular endothelial growth factor (VEGF) activities with a bifunctional diabody directed against both VEGF kinase receptors, fms-like tyrosine kinase receptor and kinase insert domain-containing receptor. Cancer Res. 61:2001;7002-7008.
    • (2001) Cancer Res. , vol.61 , pp. 7002-7008
    • Lu, D.1    Jimenez, X.2    Zhang, H.3    Wu, Y.4    Bohlen, P.5    Witte, L.6    Zhu, Z.7
  • 29
    • 0037133736 scopus 로고    scopus 로고
    • Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter
    • Lu S., Gu X., Hoestje S., Epner D.E. Identification of an additional hypoxia responsive element in the glyceraldehyde-3-phosphate dehydrogenase gene promoter. Biochim. Biophys. Acta. 1574:2002;152-156.
    • (2002) Biochim. Biophys. Acta , vol.1574 , pp. 152-156
    • Lu, S.1    Gu, X.2    Hoestje, S.3    Epner, D.E.4
  • 30
    • 0032547764 scopus 로고    scopus 로고
    • Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia
    • Mandriota S.J., Pepper M.S. Regulation of angiopoietin-2 mRNA levels in bovine microvascular endothelial cells by cytokines and hypoxia. Circ. Res. 83:1998;852-859.
    • (1998) Circ. Res. , vol.83 , pp. 852-859
    • Mandriota, S.J.1    Pepper, M.S.2
  • 31
    • 0036663073 scopus 로고    scopus 로고
    • Enhanced rate of nerve regeneration and directional errors after sciatic nerve injury in receptor protein tyrosine phosphatase sigma knock-out mice
    • McLean J., Batt J., Doering L.C., Rotin D., Bain J.R. Enhanced rate of nerve regeneration and directional errors after sciatic nerve injury in receptor protein tyrosine phosphatase sigma knock-out mice. J. Neurosci. 22:2002;5481-5491.
    • (2002) J. Neurosci. , vol.22 , pp. 5481-5491
    • McLean, J.1    Batt, J.2    Doering, L.C.3    Rotin, D.4    Bain, J.R.5
  • 32
    • 0036154335 scopus 로고    scopus 로고
    • Localization of VEGF receptor-2 (KDR/Flk-1) and effects of blocking it in oxygen-induced retinopathy
    • McLeod D.S., Taomoto M., Cao J., Zhu Z., Witte L., Lutty G.A. Localization of VEGF receptor-2 (KDR/Flk-1) and effects of blocking it in oxygen-induced retinopathy. Invest. Ophthalmol. Vis. Sci. 43:2002;474-482.
    • (2002) Invest. Ophthalmol. Vis. Sci. , vol.43 , pp. 474-482
    • McLeod, D.S.1    Taomoto, M.2    Cao, J.3    Zhu, Z.4    Witte, L.5    Lutty, G.A.6
  • 36
    • 0029018364 scopus 로고
    • Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases
    • Pe'er J., Shweiki D., Itin A., Hemo I., Gnessin H., Keshet E. Hypoxia-induced expression of vascular endothelial growth factor by retinal cells is a common factor in neovascularizing ocular diseases. Lab. Invest. 72:1995;638-645.
    • (1995) Lab. Invest. , vol.72 , pp. 638-645
    • Pe'er, J.1    Shweiki, D.2    Itin, A.3    Hemo, I.4    Gnessin, H.5    Keshet, E.6
  • 37
    • 0032546658 scopus 로고    scopus 로고
    • Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins
    • Serra-Pages C., Medley Q.G., Tang M., Hart A., Streuli M. Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins. J. Biol. Chem. 273:1998;15611-15620.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15611-15620
    • Serra-Pages, C.1    Medley, Q.G.2    Tang, M.3    Hart, A.4    Streuli, M.5
  • 38
    • 0036237242 scopus 로고    scopus 로고
    • Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue
    • Shahrara S., Volin M.V., Connors M.A., Haines G.K., Koch A.E. Differential expression of the angiogenic Tie receptor family in arthritic and normal synovial tissue. Arthritis Res. 4:2002;201-208.
    • (2002) Arthritis Res. , vol.4 , pp. 201-208
    • Shahrara, S.1    Volin, M.V.2    Connors, M.A.3    Haines, G.K.4    Koch, A.E.5
  • 40
    • 0025306895 scopus 로고
    • Different phenotypes of cultured microvessel endothelial cells obtained from bovine corpus luteum. Study by light microscopy and by scanning electron microscopy (SEM)
    • Spanel-Borowski K., van der Bosch J. Different phenotypes of cultured microvessel endothelial cells obtained from bovine corpus luteum. Study by light microscopy and by scanning electron microscopy (SEM). Cell Tissue Res. 261:1990;35-47.
    • (1990) Cell Tissue Res. , vol.261 , pp. 35-47
    • Spanel-Borowski, K.1    Van der Bosch, J.2
  • 42
    • 0029884640 scopus 로고    scopus 로고
    • Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells
    • Takagi H., King G.L., Ferrara N., Aiello L.P. Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells. Invest. Ophthalmol. Vis. Sci. 37:1996;1311-1321.
    • (1996) Invest. Ophthalmol. Vis. Sci. , vol.37 , pp. 1311-1321
    • Takagi, H.1    King, G.L.2    Ferrara, N.3    Aiello, L.P.4
  • 43
    • 0028883260 scopus 로고
    • Comparative analysis of vascular endothelial growth factor receptors on retinal and aortic vascular endothelial cells
    • Thieme H., Aiello L.P., Takagi H., Ferrara N., King G.L. Comparative analysis of vascular endothelial growth factor receptors on retinal and aortic vascular endothelial cells. Diabetes. 44:1995;98-103.
    • (1995) Diabetes , vol.44 , pp. 98-103
    • Thieme, H.1    Aiello, L.P.2    Takagi, H.3    Ferrara, N.4    King, G.L.5
  • 44
    • 0036352775 scopus 로고    scopus 로고
    • Microvascular endothelial cells differ in basal and hypoxia-regulated expression of angiogenic factors and their receptors
    • Tscheudschilsuren G., Aust G., Nieber K., Schilling N., Spanel-Borowski K. Microvascular endothelial cells differ in basal and hypoxia-regulated expression of angiogenic factors and their receptors. Microvasc. Res. 63:2002;243-251.
    • (2002) Microvasc. Res. , vol.63 , pp. 243-251
    • Tscheudschilsuren, G.1    Aust, G.2    Nieber, K.3    Schilling, N.4    Spanel-Borowski, K.5
  • 45
    • 0029758798 scopus 로고    scopus 로고
    • Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia
    • Waltenberger J., Mayr U., Pentz S., Hombach V. Functional upregulation of the vascular endothelial growth factor receptor KDR by hypoxia. Circulation. 94:1996;1647-1654.
    • (1996) Circulation , vol.94 , pp. 1647-1654
    • Waltenberger, J.1    Mayr, U.2    Pentz, S.3    Hombach, V.4
  • 46
    • 0033562832 scopus 로고    scopus 로고
    • Extracellular matrix inhibits apoptosis and enhances endothelial cell differentiation by a NfkappaB-dependent mechanism
    • Wang W., Passaniti A. Extracellular matrix inhibits apoptosis and enhances endothelial cell differentiation by a NfkappaB-dependent mechanism. J. Cell Biochem. 73:1999;321-331.
    • (1999) J. Cell Biochem. , vol.73 , pp. 321-331
    • Wang, W.1    Passaniti, A.2
  • 49
    • 0035136729 scopus 로고    scopus 로고
    • Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease
    • Yu D.Y., Cringle S.J. Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease. Prog. Retin. Eye Res. 20:2001;175-208.
    • (2001) Prog. Retin. Eye Res. , vol.20 , pp. 175-208
    • Yu, D.Y.1    Cringle, S.J.2
  • 50
    • 0035895711 scopus 로고    scopus 로고
    • Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family
    • Zachary I., Gliki G. Signaling transduction mechanisms mediating biological actions of the vascular endothelial growth factor family. Cardiovasc. Res. 49:2001;568-581.
    • (2001) Cardiovasc. Res. , vol.49 , pp. 568-581
    • Zachary, I.1    Gliki, G.2


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