Octachlorodipropyl ether (S-2) mosquito coils are inadequately studied for residential use in Asia and illegal in the United States

Environmental Health Perspectives

Volumn 111, Issue 12, 2003, Pages 1439-1442

  Krieger, Robert I ^a   Dinoff, Travis M ^a   Zhang, Xiaofei ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Bis(chloromethyl)ether; Chloroalkyl ether; d allethrin; Lung carcinogen; Mosquito coil; Octachlorodipropyl ether; S 2

Indexed keywords

ALLETHRIN; BIS(CHLOROMETHYL) ETHER; DYE; ETHER DERIVATIVE; FILLER; FORMALDEHYDE; FUNGICIDE; HYDROCHLORIC ACID; INSECT REPELLENT; INSECTICIDE; OCTACHLORODIPROPYL ETHER; PYRETHROID; UNCLASSIFIED DRUG;

AEROSOL; AIR MONITORING; AMBIENT AIR; ARTICLE; ASIA; CHEMICAL COMPOSITION; COMBUSTION; CONTROLLED STUDY; DECISION MAKING; ENVIRONMENTAL EXPOSURE; GEOGRAPHY; LEGAL ASPECT; LONG TERM EXPOSURE; LUNG CARCINOMA; MOSQUITO; NONHUMAN; PRIORITY JOURNAL; PROTECTIVE EQUIPMENT; REGISTRATION; RESIDENTIAL CARE; TROPICS; UNITED STATES; VAPORIZER;

INSECTA;

EID: 0141517480     PISSN: 00916765     EISSN: None     Source Type: Journal    
DOI: 10.1289/ehp.6177     Document Type: Article

References (33)

1. Adolphi H. 1958. Examination of a pyrethrum synergist - preliminary information. Pyrethrum Post 4:3-5.
2. ATSDR. 1989. Toxicological Profile for Bis(chloromethyl)ether. Atlanta, GA:Agency for Toxic Substances and Disease Registry.
3. Backe F, Sperber H. 1960. Octachlorodipropyl ether. U.S. Patent 2,913,500. Chem Abstr 54:3203e.
4. California EPA. 1994. Office of Environmental Health Hazard Assessment. Safe Drinking Water and Toxic Enforcement Act of 1986, Status Report: No Significant Risk Levels for Carcinogens and Acceptable Intake Levels for Reproductive Toxicants. Sacramento, CA:California Environmental Protection Agency.
5. Cheng V, Lee HR, Chen CS. 1992. Morphological changes inthe respiratory system of mice after inhalation of mosquito-coil smoke. Toxicol Lett 62:163-177.
6. Cuppit L. 1980. Fate of Toxic and Hazardous Materials in the Air Environment. Research Triangle Park, NC:Atmospheric Chemistry and Physics Laboratory, U.S. Environmental Protection Agency.
7. Fishbein L, Fawkes J, Folks HL, Thompson. 1968. Thin-layer chromatography of rat bile and urine following intravenous administration of the pesticidal synergist octachlorodipropyl ether. J Chromatogr 37:256-263.
8. Franke S, Hildebrandt S, Francke W. 1995. The occurrence of chlorinated bis-(propyl) ethers in the Elbe River and tributaries. Naturwissenshaften 82:80-83.
9. Frankel LS, McCallum K, Collier L. 1974. Formation of bis-(chloromethyl) ether from formaldehyde and hydrogen chloride. Environ Sci Technol 8:356-359.
10. Hayashi A. 1969. Synergistic effect of octachlorodipropylether (S-421). Botyu-Kagaku 34:189-192.
11. IARC. 1987. Overall evaluations of carcinogenicity: an updating of IARC monographs volumes 1 to 42. IARC Monogr Eval Carcinog Risks Hum 7(suppl):1-440.
12. Kallos GJ, Solomon RA, 1973. Investigations of the formation of bis-(chloromethyl)ether in simulated hydrogen chlorideformaldehyde atmospheric environments. Am Ind Hyg Assoc J 34:469-473.
13. Langelaan FCGM, Nielen MWF. 1989. Determination of trace levels of chloromethyl-methylether and bis(chloromethyl)ether in air. Int J Environ Anal Chem 36:27-34.
14. Liu WK, Sun SE. 1988. Ultrastructural changes of tracheal epithelium and alveolar macrophages of rats exposed to mosquito coil smoke. Toxicol Lett 41:145-147.
15. Miyazaki T. 1982. Residues of the synergist S-421 in human milk collected from the Tokyo metropolitan area. Bull Environ Contam Toxicol 29:566-569.
16. Miyazaki T, Kaneko S, Horii S, Yamagishi T. 1981. Identification of the synergist bis-(2,3,3,3-tetrachloropropyl)ether in human milk. Bull Environ Contam Toxicol 26: 421-423.
17. Mrusek K. 1996. The usage of S-2 in household insecticide products. In: Proceedings of the International Seminar an Recent Development of Mosquito Coils: Efficacy, Toxicology, Environmental Impact and Legislation, 5-7 December 1996, Penang, Malaysia. Penang, Malaysia:Vector Control Research Unit, Universiti Sains Malaysia, 29-32.
18. Mulla MS, Thavara U, Tawatsin A, Kong-Ngamsuk W, Chompoosri J. 2001. Mosquito burden and impact on the poor: measures and costs for personal protection in some communities in Thailand. J Am Mosquito Control Assoc 17:153-159.
19. Nelson N. 1976. The chloroethers - occupational carcinogens: a summary of laboratory and epidemiology studies. Ann NY Acad Sci 271:81-90.
20. NTP. 2002. Report on Carcinogens, 10th ad. Research Triangle Park, NC:National Toxicology Program.
21. Pauluhn J. 1996. Assessment of mosquito coil smoke for its potential to induce irritation-related respiratory tract changes on nose-only exposed rats: a comparison of different methods. In: Proceedings of the International Seminar on Recent Development of Mosquito Coils: Efficacy, Toxicology, Environmental Impact and Legislation, 5-7 December 1996, Penang, Malaysia. Penang, Malaysia:Vector Control Research Unit, Universiti Sains Malaysia, 33-49.
22. Pauluhn J. 2002, Risk assessment of mosquito coil smoke - new critical evidence. Presentated at the 11th Annual Workshop on Biology & Control of Vectors & Urban Pests, 6-8 May 2002, Penang, Malaysia.
23. Pauluhn J, Mohr U. 2000. Inhalation studies in laboratory animals - current concepts and alternatives. Toxicol Pathol 28:734-753.
24. Sittig M. 1981. Handbook of Toxic and Hazardous Chemicals. Park Ridge, NJ:Noyes Publications.
25. Spiller N. 1996. Are active ingredient cocktails of any value in mosquito coils? Proceedings of the International Seminar on Recent Development of Mosquito Coils: Efficacy, Toxicology, Environmental Impact and Legislation, 5-7 December 1996, Penang, Malaysia. Penang, Malaysia:Vector Control Research Unit, Universiti Sains Malaysia, 12-18.
26. Tou J, Kallos G. 1974. Kinetic study of the stabilities of chloromethyl methyl ether and bis(chloromethyl) ether in humid air. Anal Chem 46:1866-1869.
27. Tou J, Kallos G. 1976. Possible formation of bis(chloromethyl ether) ether from the reactions of formaldehyde and chloride ion. Anal Chem 48:958-963.
28. U.S. EPA, 2003. Integrated Risk Information System. Washington, DC:U.S. Environmental Protection Agency. Available: http.,//www.epa.gov/iris/subst/0375.htm#top [accessed 13 May 2003].
29. Van Duuren BL, Sivak A, Goldschmidt BM, Katz C, Melchionne S. 1969. Carcinogenicity of halo-ethers. J Natl Cancer Inst 43:481-486 (1969).
30. WHO. 1998a. Pesticides Evaluation Scheme, Division of Control of Tropical Diseases, Guideline Specifications for Household Insecticide Products. Geneva:World Health Organization.
31. WHO. 1998b. Environmental Health Criteria 201, Selected Chloroalkyl Ethers. Geneva:World Health Organization.
32. WHO. 2003. Communicable Diseases 2002. In: Global Defense against the Infectious Disease Threat (Kindhauser MK, ed). Geneva:World Health Organization, 32-53.
33. Xue SZ, Quian C, Tang GF, Wang ZQ, Zhou DH, Deng J, et al. 1988. Epidemiological investigations on the lung cancer among chloro-methyl-ether exposures. In: Occupational Health in Industrialization and Modernization (Xue SZ, Liang Y, eds). Shanghai:Shanghai Medical University Press, 75-80.