Tumorigenic conversion of endothelial cells

Experimental and Molecular Pathology

Volumn 75, Issue 2, 2003, Pages 154-159

  Krump Konvalinkova, Vera ^a,c   Kleideiter, Elke ^b   Friedrich, Ulrike ^b,d   Klotz, Ulrich ^b   Kirkpatrick, C James ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^c UNIVERSITY OF MUNICH   (Germany)

^d Pharmacy Department of the Hospital   (Germany)

Author keywords

Angiosarcoma; Cell adhesion molecules; Cytokines; Endothelial cell lines; Telomerase; Telomere length; Tumorigenesis

Indexed keywords

CAVEOLIN; CD31 ANTIGEN; CYTOKINE; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; PROTEIN P53; TELOMERASE; VON WILLEBRAND FACTOR;

ANGIOGENESIS; ANGIOSARCOMA; ARTICLE; CARCINOGENESIS; CELL ISOLATION; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; INFLAMMATION; PROTEIN EXPRESSION; TELOMERE; TUMOR CELL LINE; UMBILICAL VEIN;

EID: 0141516369     PISSN: 00144800     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-4800(03)00074-1     Document Type: Article

References (25)

1. Amo Y., Masuzawa M., Hamada Y., Katsuoka K. Expression of vascular endothelial growth factor in human hemangiosarcoma cell line (ISO-HAS). Arch. Dermatol. Res. 293:2001;296-301.
2. Bryan T.M., Enlezou A., Gupta J., Bacchetti S., Reddel R.R. Telomere elongation in immortal human cells without detectable telomerase activity. EMBO J. 14:1995;4240-4248.
3. Chen Z., Smith K.J., Skelton H.G. III, Barrett T.L., Greenway H.T. Jr., Lo S.C. Telomerase activity in Kaposi's sarcoma, squamous cell carcinoma, and basal cell carcinoma. Exp. Biol. Med. 226:2001;753-757.
4. de Lange T. Protection of mammalian telomeres. Oncogene. 21:2002;532-540.
5. Dhaene K., van Marck E., Parwaresch R. Telomeres, telomerase and cancer an up-date . Virchows Arch. 437:2000;1-16.
6. Dunham M.A., Neumann A.A., Fasching C.L., Reddel R.R. Telomere maintenance by recombination in human cells. Nat. Genet. 26:2000;447-450.
7. Endo A., Kano Y., Mihara K., Orita K., Namba M. Alteration in the retinoblastoma gene associated with immortalization of human fibroblasts treated with 60Co gamma rays. J. Cancer Res. Clin. Oncol. 119:1993;522-526.
8. Esrig D., Spruck C.H. III, Nichols P.W., Chaiwan B., Steven K., Groshen S., Chen S.C., Skinner D.G., Jones P.A., Cote R.J. 53 nuclear protein accumulation correlates with mutations in the 53 gene, tumor grade and stage in bladder cancer. Am. J. Pathol. 143:1993;1389-1397.
9. Fiucci G., Ravid D., Reich R., Liscovitch M. Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene. 21:2002;2365-2375.
10. Friedrich U., Griese E., Schwab M., Fritz P., Thon K., Klotz U. Telomere length in different tissues of elderly patients. Mech. Ageing Dev. 119:2000;89-99.
11. Friedrich U., Schwab M., Griese E.U., Fritz P., Klotz U. Telomere in neonates new insights in fetal hematopoiesis . Pediatr. Res. 49:2001;252-256.
12. Garbe C., Krasagakis K., Zoublis C.C., Schroder K., Kruger S., Stadler R., Orfanos C.E. Antitumor activities of interferon alpha, beta, and gamma and their combinations on human melanoma cells in vitro changes of proliferation, melanin synthesis, and immunophenotype . J. Invest. Dermatol. 95:1990;231S-237S.
13. Jaffe E.A., Nachman R.L., Becker C.G., Minick R. Culture of human endothelial cells derived from umbilical veins. Identification by morphologic and immunologic criteria. J. Clin. Invest. 52:1973;2745-2756.
14. Krump-Konvalinkova V., Bittinger F., Unger R.E., Peters K., Lehr H.-A., Kirkpatrick C.J. Generation of human pulmonary microvascular endothelial cell lines. Lab. Invest. 81:2001;1717-1727.
15. Lawley T.J., Kubota Y. Induction of morphologic differentiation of endothelial cells in culture. J. Invest. Dermatol. 93:1989;59S-61S.
16. Levine A.J. p53, the cellular gatekeeper for growth and division. Cell. 88:1997;323-331.
17. Liu J., Wang X.B., Park D.S., Lisanti M.P. Caveolin-1 expression enhances endothelial capillary tubules formation. J. Biol. Chem. 277:2002;10661-10668.
18. Masuzawa M., Fujimura T., Hamada Y., Fujita Y., Hara H., Nishiyama S., Katsuoka K., Tamauchi H., Sakurai Y. Establishment of a human hemangiosarcoma cell line (ISO-HAS). Int. J. Cancer. 81:1999;305-308.
19. Morgan M.B., Stevens G.L., Tannenbaum M., Salup R. Expression of the caveolins in dermal vascular tumors. J. Cutan. Pathol. 28:2001;24-28.
20. Shay J.W., Bacchetti S. A survey of telomerase activity in human cancer. Eur. J. Cancer. 33:1977;787-791.
21. Unger R.E., Krump-Konvalinkova V., Peters K., Kirkpatrick C.J. In vitro expression of endothelial phenotype comparative study of primary isolated cells and cell lines, including the novel cell line, HPMEC-ST1.6R . Microvasc Res. 64:2002;384-397.
22. Wiechen K., Diatchenko L., Agoulnik A., Scharff K.M., Schrober H., Arlt K., Zhumabayeva B., Siebert P.D., Dietel M., Schäfer R., Sers C. Caveolin-1 is down regulated in human ovarian carcinoma and acts as a candidate tumor suppressor gene. Am. J. Pathol. 159:2001;1635-1643.
23. Wiechen K., Sers C., Agoulnik A., Arlt K., Dietel M., Schlag P.M., Schneider U. Down-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcoma. Am. J. Pathol. 15:2001;833-839.
24. Yang J., Chang E., Cherry A.M., Bangs C.D., Oei Y., Bodnar A., Bronstein A., Chiu C.P., Herron G.S. Human endothelial cell life extension by telomerase expression. J. Biol. Chem. 274:1999;26141-26148.
25. Yazawa M., Okuda M., Setoguchi A., Nishimura R., Sasaki N., Hasegawa A., Watari T., Tsujimoto H. Measurement of telomerase activity in dog tumors. J. Vet. Med. Sci. 61:1999;1125-1129.