Duration of untreated psychosis and outcome of schizophrenia: Delay in intensive psychosocial treatment versus delay in treatment with antipsychotic medication

Schizophrenia Bulletin

Volumn 29, Issue 2, 2003, Pages 341-348

  De Haan, Lieuwe ^a   Linszen, Don H ^a   Lenior, Marie E ^a   De Win, Evelyne Doderlein ^a   Gorsira, Rob ^a  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

Author keywords

Delay in psychosocial treatment; Duration of untreated psychosis; Outcome; Schizophrenia

Indexed keywords

NEUROLEPTIC AGENT;

ADULT; ARTICLE; DISEASE COURSE; DISEASE DURATION; FEMALE; GENDER; HOSPITALIZATION; HUMAN; MAJOR CLINICAL STUDY; MALE; NEGATIVE SYNDROME; ONSET AGE; PRIORITY JOURNAL; PSYCHOSIS; PSYCHOSOCIAL CARE; RELAPSE; SCHIZOPHRENIA; TREATMENT OUTCOME;

EID: 0141506972     PISSN: 05867614     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.schbul.a007009     Document Type: Article

References (24)

1. American Psychiatric Association. DSM-III-R: Diagnostic and Statistical Manual of Mental Disorders. 3rd ed., revised. Washington, DC: APA, 1987.
2. American Psychiatric Association. DSM-IV: Diagnostic and Statistical Manual of Mental Disorders. 4th ed. Washington, DC: APA, 1994.
3. Anderson, C.M.; Reiss, D.J.; and Hogarty, G.E. Schizophrenia and the Family. New York, NY: Guilford Press, 1986.
4. Barnes, T.R.E.; Hutton, S.B.; Chapman, M.J.; Mutsatsa, S.; Puri, B.K.; and Joyce, E.M. West London first-episode study of schizophrenia: Clinical correlates of duration of untreated psychosis. British Journal of Psychiatry, 177:207-211, 2001.
5. Craig, T.J.; Bromet, E.J.; Fennig, S.; Tanenberg-Karant, M.; Lavelle, J. ; and Galambos, N. Is there an association between duration of untreated psychosis and 24-month clinical outcome in a first-admission series? American Journal of Psychiatry, 157(1):60-66, 2000.
6. Crow, T.J.; MacMillan, J.F.; Johnson, A.L.; and Johnstone, E.C., 2nd. A randomized controlled trial of prophylactic neuroleptic treatment. British Journal of Psychiatry, 148:120-127, 1986.
7. de Haan, L.; van der Gaag, M.; and Wolthaus, J. Duration of untreated psychosis and the long-term course of schizophrenia. European Psychiatry, 15:264-267, 2000.
8. Dixon, W.J.; Brown, M.B.; Engelman, L.; and Jennrich, R.I., eds. BMDP Statistical Software Manual. Vol. 2. Berkeley, CA: University of California Press, 1990.
9. Haas, G.L., and Sweeney, J.A. Premorbid and onset features of first-episode schizophrenia. Schizophrenia Bulletin, 18(3):373-386, 1992.
10. Ho, B.C.; Andreasen, N.C.; Flaum, M.; Nopoulos, P.; and Miller, D. Untreated initial psychosis: Its relation to quality of life and symptom remission in first-episode schizophrenia. American Journal of Psychiatry, 157:808-815, 2000.
11. Hoff, A.L.; Sakuma, M.; Razi, K.; Heydebrand, G.; Csernansky, J.G.; and Delisi, L.E. Lack of association between duration of untreated illness and severity of cognitive and structural brain deficits at the first episode of schizophrenia. American Journal of Psychiatry, 157:1824-1828, 2000.
12. Hosmer, D.W., and Lemeshow, S. Applied Logistic Regression. New York, NY: John Wiley and Sons, 1989.
13. Johnstone, E.C.; Owens, D.G.; Crow, T.J.; and Davis, J.M. Does a four-week delay in the introduction of medication alter the course of functional psychosis? Journal of Psychopharmacology, 13:238-244, 1999.
14. Kay, S.R.; Opler, L.A.; and Fishbein, A. Positive and Negative Syndrome Scale (PANSS) rating manual. San Rafael, CA: Social and Behavioral Sciences Documents, 1987.
15. Larsen, T.K.; McGlashan, T.H.; Johannessen, J.O.; and Vibe-Hansen, L. First-episode schizophrenia: II. Premorbid patterns by gender. Schizophrenia Bulletin, 22(2):257-269, 1996.
16. Lehman, A.F., and Steinwachs, D.M. Translating research into practice: The Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations. Schizophrenia Bulletin, 24(1):1-10, 1998.
17. Liberman, R.P.; Mueser, K.T.; Wallace, C.J.; Jacobs, H.E.; Eckman, T.; and Massel, H.K. Training skills in the psychiatrically disabled: Learning coping and competence. Schizophrenia Bulletin, 12(4):631-647, 1986.
18. Linszen, D.; Dingemans, P.; Van der Does, J.W.; Nugter, A.; Scholte, P.; Lenior, R.; and Goldstein, M.J. Treatment, expressed emotion and relapse in recent onset schizophrenic disorders. Psychological Medicine, 26:333-342, 1996.
19. Linszen, D.H.; Lenior, M.; de Haan, L.; Dingemans, P.; and Gersons, B.P.R. Early intervention, untreated psychosis and the course of early schizophrenia. British Journal of Psychiatry, 172(Suppl 33):84-89, 1998.
20. Loebel, A.D.; Lieberman, J.A.; Alvir, J.M.J.; Mayerhoff, D.I.; Geisler, S.H.; and Szymanski, S.R. Duration of psychosis and outcome in first-episode schizophrenia. American Journal of Psychiatry, 149:1183-1188, 1992.
21. Mojtabai, R.; Nicholson, R.A.; and Carpenter, B.N. Role of psychosocial treatments in management of schizophrenia: A meta-analytic review of controlled outcome studies. Schizophrenia Bulletin, 24(4):569-587, 1998.
22. Norman, R.G., and Malla, A.K. Duration of untreated psychosis: A critical examination of the concept and its importance. Psychological Medicine, 31:381-400, 2001.
23. Norusis, M.J. SPSS/PC+ 4.0 Base Manual for the IBM PC/XT/AT and PS/2. Chicago, IL: SPSS Inc., 1990.
24. Robinson, D.; Woerner, M.G.; Alvir, J.M.J.; Bilder, R.; Goldman, R.; Geisler, S.; Koreen, A.; Sheitman, B.; Chakos, M.; Mayerhoff, D.; and Lieberman, J.A. Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives of General Psychiatry, 56:241-247, 1999.