Differences between the ε and γ subunits of the acetylcholine receptor (AChR) may be significant in autoimmune myasthenia gravis

Annals of the New York Academy of Sciences

Volumn 998, Issue , 2003, Pages 336-338

  Ragheb, Samia ^a   Lisak, Robert P ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Acetyleholine receptor; Epitope; Myasthenia gravis

Indexed keywords

CHOLINERGIC RECEPTOR; CHOLINERGIC RECEPTOR ALPHA; CHOLINERGIC RECEPTOR ANTIBODY; CHOLINERGIC RECEPTOR EPSILON; CHOLINERGIC RECEPTOR GAMMA; MEMBRANE PROTEIN; PEPTIDE DERIVATIVE; RECEPTOR SUBUNIT; UNCLASSIFIED DRUG; EPITOPE; NICOTINIC RECEPTOR; PEPTIDE; PROTEIN SUBUNIT;

B LYMPHOCYTE; CELL DIFFERENTIATION; CONFERENCE PAPER; HUMAN; IMMUNE RESPONSE; IMMUNE SYSTEM; IN VITRO STUDY; MONONUCLEAR CELL; MOTONEURON; MYASTHENIA GRAVIS; PATHOGENESIS; SKELETAL MUSCLE; T LYMPHOCYTE; THYMUS; ARTICLE; COMPARATIVE STUDY; IMMUNOLOGY; METABOLISM;

EPITOPES; HUMANS; MUSCLE, SKELETAL; MYASTHENIA GRAVIS; PEPTIDES; PROTEIN SUBUNITS; RECEPTORS, NICOTINIC; THYMUS GLAND;

EID: 0141504313     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1196/annals.1254.037     Document Type: Conference Paper

References (4)

1. PATRICK, J. & J. LINDSTROM. 1973. Autoimmune response to acetylcholine receptors. Science 180: 871-872.
2. RAGHEB, S. & R.P. LISAK. 1994. The immunopathogenesis of acquired (autoimmune) myasthenia gravis. In Handbook of Myasthenia Gravis and Myasthenic Syndromes, pp. 239-276. Dekker, New York.
3. GEUDER, K.I., A. MARX, V. WITZEMANN et al. 1992. Pathogenetic significance of fetal-type acetylcholine receptors on thymic myoid cells in myasthenia gravis. Dev. Immunol. 2: 69-75.
4. TAKAI, T., M. NODA, M. MISHINA et al. 1985. Cloning, sequencing, and expression of cDNA for a novel subunit of acetylcholine receptor from calf muscle. Nature 315: 761-764.