Synthesis and properties of halogenated 7-deaza-2′-deoxyxanthosine and protected derivatives for oligonucleotide synthesis

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 1239-1241

  Seela, F ^a   Shaikh, K ^a   Wiglenda, T ^a  

^a UNIVERSITY OF OSNABRÜCK   (Germany)

Author keywords

7 Deaza 2 deoxyxanthosine; Halogen derivatives; Oligonucleotides

Indexed keywords

7 DEAZA 2' DEOXYXANTHOSINE DERIVATIVE; BROMINE DERIVATIVE; IODINE DERIVATIVE; NUCLEOSIDE DERIVATIVE; OLIGONUCLEOTIDE; UNCLASSIFIED DRUG;

BROMINATION; CONFERENCE PAPER; DEMETHYLATION; DERIVATIZATION; IODINATION; MOLECULAR STABILITY; NUCLEIC ACID SYNTHESIS;

DEOXYRIBONUCLEOSIDES; GLYCOSIDES; INDICATORS AND REAGENTS; MOLECULAR STRUCTURE; OLIGODEOXYRIBONUCLEOTIDES;

EID: 0141484691     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120022845     Document Type: Conference Paper

References (4)

1. Seela, F.; Driller, H.; Liman, U. 7-Desaza-isostere von 2′-desoxyxanthosin and 2′-desoxyspongosin-synthese via glycosylierung von 2,4-dichlor-7H-pyrrolo[2,3-d]pyrimidin. Liebigs Ann. Chem. 1985, 312 pp.
2. Ramzaeva, N.; Seela, F. 7-Substituted 7-deaza-2′-deoxyguanosines; Regioselective halogenation of pyrrolo[2,3-d]pyrimidine nucleosides. Helv. Chim. Acta. 1995, 78, 1083 pp.
3. Milligan, J.F.; Krawczyk, S.H.; Wadwani, S.; Matteucci, M.D. An anti-parallel triple helix motif with oligodeoxynucleotides containing 2′-deoxyguanosine and 7-deaza-2′-deoxy-xanthosine. Nucleic Acids Res. 1993, 21, 327 pp.
4. Pitsch, S.; Krishnamurthy, R.; Bolli, M.; Wendeborn, S.; Holzner, A.; Mirton, M.; Lesueur, C.; Schlönvogt, I.; Jaun, B.; Eschenmoser, A. Pyranosyl-RNA('p-RNA'): Base-pairing selectivity and potential to replicate. Helv. Chim. Acta. 1995, 78, 1621 pp.