Synthesis of trans-L/D-2-(tert-butoxycarbonylaminomethyl)-4-(thymin-1-yl) pyrrolidin-1-yl acetic acid

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 1285-1288

  Kumar, Vaijayanti A ^a   Meena, ^a  

^a NATIONAL CHEMICAL LABORATORY   (India)

Author keywords

PNA DNA RNA complexes; Pyrrolidine PNA

Indexed keywords

2 (TERT BUTOXYCARBONYLAMINOMETHYL) 4 (THYMIN 1 YL)PYRROLIDIN 1 YLACETIC ACID; COMPLEMENTARY DNA; COMPLEMENTARY RNA; MONOMER; OLIGOMER; PEPTIDE NUCLEIC ACID; PYRROLIDINE DERIVATIVE; UNCLASSIFIED DRUG;

COMPLEX FORMATION; CONFERENCE PAPER; DNA BINDING; MOLECULAR GENETICS; STEREOCHEMISTRY; SYNTHESIS;

ACETIC ACIDS; BASE SEQUENCE; DNA; HYDROGEN BONDING; OLIGODEOXYRIBONUCLEOTIDES; PEPTIDE NUCLEIC ACIDS; PYRROLIDINES; STEREOISOMERISM; THYMINE;

EID: 0141484681     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120022947     Document Type: Conference Paper

References (4)

1. Kumar, V.A. Structural pre-organization of peptide nucleic acids: Chiral cationic analogs with five- or six-membered ring structures. Eur. J. Org. Chem. 2002, 2021 pp.
2. Puschl, A.; Tedeschi, T.; Nielsen, P.E. Pyrrolidine PNA: A novel conformationally restricted PNA analogue. Org. Lett. 2000, 2, 4161-4163.
3. Hickman, D.T.; King, P.M.; Cooper, M.A.; Slater, J.M.; Mickelfield, J. Unusual RNA and DNA binding properties of a novel pyrrolidine-amide oligonucleotide mimic (POM). Chem. Commun. 2000, 2251-2252.
4. Kumar, V.A.; Pallan, P.S.; Meena; Ganesh, K.N. Pyrrolidine nucleic acids: DNA/PNA oligomers with 2-hydroxy/aminomethyl-4-(thymin-1-yl)pyrrolidine-N-acetic acid. Org. Lett. 2001, 3, 1269-1272.