Aryl-β-C-LNA monomers as universal hybridization probes

Nucleosides, Nucleotides and Nucleic Acids

Volumn 22, Issue 5-8, 2003, Pages 1317-1319

  Babu, B Ravindra ^a   Wengel, Jesper ^a  

^a UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

LNA, locked nucleic acid; Universal bases; Universal hybridization

Indexed keywords

2' O METHYLENE RIBONUCLEIC ACID; LOCKED NUCLEIC ACID; MONOMER; NUCLEIC ACID; OLIGONUCLEOTIDE; PYRENE DERIVATIVE; PYRENYL LOCKED NUCLEIC ACID; RNA DERIVATIVE; UNCLASSIFIED DRUG;

CONFERENCE PAPER; HYBRIDIZATION;

BASE SEQUENCE; NUCLEIC ACID CONFORMATION; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDE PROBES; OLIGONUCLEOTIDES, ANTISENSE;

EID: 0141484677     PISSN: 15257770     EISSN: None     Source Type: Journal    
DOI: 10.1081/NCN-120022955     Document Type: Conference Paper

References (4)

1. Babu, B.R.; Wengel, J. Universal hybridization using LNA (locked nucleic acid) containing a novel pyrene LNA nucleotide monomer. Chem. Commun. 2001, 2114 pp.
2. Babu, B.R.; Prasad, A.K.; Trikha, S.; Thorup, N.; Parmar, V.S.; Wengel, J. Conformationally locked aryl C-nucleosides: synthesis of phosphoramidite monomers and incorporation into single-stranded DNA and LNA (locked nucleic acid). J. Chem. Soc., Perkin Trans 1 2002, 2509 pp.
3. Loakes, D. The applications of universal DNA base analogues. Nucleic Acids Res. 2001, 29, 2437 pp.
4. Wengel, J. Synthesis of 3′-C- and 4′-C-branched oligodeoxynucleotides and the development of locked nucleic acid (LNA). Acc. Chem. Res. 1999, 32, 301 pp.