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Volumn 22, Issue 5-8, 2003, Pages 1639-1645
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Diastereomeric process control in the synthesis of 2′ -O-(2-methoxyethyl) oligoribonucleotide phosphorothioates as antisense drugs
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Author keywords
Activators; Coupling; Oligomerization; Phosphate protecting group; Process control; Stereochemistry
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Indexed keywords
2' O (2 METHOXYETHYL) OLIGORIBONUCLEOTIDE;
ANTISENSE OLIGONUCLEOTIDE;
NUCLEOSIDE;
NUCLEOTIDE;
PHOSPHITE;
PHOSPHORAMIDIC ACID;
PHOSPHOROTHIOIC ACID DERIVATIVE;
UNCLASSIFIED DRUG;
CHEMICAL REACTION;
CONFERENCE PAPER;
DIASTEREOISOMER;
DRUG SYNTHESIS;
OLIGOMERIZATION;
PHOSPHORUS NUCLEAR MAGNETIC RESONANCE;
PROCESS CONTROL;
STEREOCHEMISTRY;
BASE SEQUENCE;
DRUG DESIGN;
INDICATORS AND REAGENTS;
MAGNETIC RESONANCE SPECTROSCOPY;
OLIGONUCLEOTIDES;
ORGANOPHOSPHORUS COMPOUNDS;
PHOSPHATES;
RNA, ANTISENSE;
STEREOISOMERISM;
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EID: 0141484530
PISSN: 15257770
EISSN: None
Source Type: Journal
DOI: 10.1081/NCN-120023089 Document Type: Conference Paper |
Times cited : (9)
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References (0)
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