The N-terminus is unstructured, but not dynamically disordered, in the complex between HK022 Nun protein and λ-phage BoxB RNA hairpin

FEBS Letters

Volumn 553, Issue 1-2, 2003, Pages 95-98

  Stuart, Ashley C ^b   Gottesman, Max E ^a   Palmer III, Arthur G ^a  

^a Och Spine at New York Presbyterian Hospitals   (United States)

^b ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Arginine rich motif; Disordered protein; Dynamics; Nuclear magnetic resonance spin relaxation; Transcription termination

Indexed keywords

BOXB RNA; HK022 NUN PROTEIN; PROTEIN; RNA BINDING PROTEIN; UNCLASSIFIED DRUG;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIOPHAGE; CARBON NUCLEAR MAGNETIC RESONANCE; NUCLEAR OVERHAUSER EFFECT; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN SECONDARY STRUCTURE; TRANSCRIPTION TERMINATION;

EID: 0141459688     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0014-5793(03)00979-7     Document Type: Article

References (30)

1. Das A. Annu. Rev. Biochem. 62:1993;893-930.
2. Hung S.C., Gottesman M.E. J. Mol. Biol. 247:1995;428-442.
3. Nudler E., Gottesman M.E. Genes Cells. 7:2002;755-768.
4. King R.A., Madsen P.L., Weisberg R.A. J. Bacteriol. 182:2000;456-462.
5. Robert J., Sloan S.B., Weisberg R.A., Gottesman M.E., Robledo R., Harbrecht D. Cell. 51:1987;483-492.
6. Washburn R.S., Wong Y., Gottesman M.E. J. Mol. Biol. 329:2003;655-662.
7. Weiss M.A., Narayana N. Biopolymers. 48:1998;167-180.
8. Legault P., Li J., Mogridge J., Kay L.E., Greenblatt J. Cell. 93:1998;289-299.
9. Schärpf M., Sticht H., Schweimer K., Boehm M., Hoffmann S., Rösch P. Eur. J. Biochem. 267:2000;2397-2408.
10. Faber C., Schärpf M., Becker T., Sticht H., Rösch P. J. Biol. Chem. 276:2001;32064-32070.
11. Chattopadhyay S., Hung S.C., Stuart A.C., Palmer A.G., Garcia-Mena J., Das A., Gottesman M.E. Proc. Natl. Acad. Sci. USA. 92:1995;12131-12135.
12. Schwarzinger S., Kroon G.J.A., Foss T.R., Chung J., Wright P.E., Dyson H.J. J. Am. Chem. Soc. 123:2001;2970-2978.
13. Spera S., Bax A. J. Am. Chem. Soc. 113:1991;5490-5492.
14. Wishart D.S., Bigam C.G., Holm A., Hodges R.S., Sykes B.D. J. Biomol. NMR. 5:1995;67-81.
15. Palmer A.G. Annu. Rev. Biophys. Biomol. Struct. 30:2001;129-155.
16. Palmer A.G., Kroenke C.D., Loria J.P. Methods Enzymol. 339:2001;204-238.
17. Milligan J.F., Groebe D.R., Witherell G.W., Uhlenbeck O.C. Nucleic Acids Res. 15:1987;8783-8798.
18. Sambrook, J., Fritsch, E.F. and Maniatis, T. (1989) Molecular Cloning, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
19. Cavanagh, J., Fairbrother, W.J., Palmer, A.G. and Skelton, N.J. (1996) Protein NMR Spectroscopy: Principles and Practice, Academic Press, San Diego, CA.
20. Farrow N.A., Muhandiram R., Singer A.U., Pascal S.M., Kay C.M., Gish G., Shoelson S.E., Pawson T., Forman-Kay J.D., Kay L.E. Biochemistry. 33:1994;5984-6003.
21. Kraulis P.J. J. Magn. Reson. 84:1989;627-633.
22. Gronenborn A.M., Clore G.M. J. Biomol. NMR. 4:1994;455-458.
23. Wüthrich, K. (1986) NMR of Proteins and Nucleic Acids, Wiley, New York.
24. Härd T. Q. Rev. Biophys. 32:1999;57-98.
25. Rost B., Sander C. J. Mol. Biol. 232:1993;584-599.
26. Bracken C., Carr P.A., Cavanagh J., Palmer A.G. J. Mol. Biol. 285:1999;2133-2146.
27. Spolar R.S., Record M.T. Science. 263:1994;777-784.
28. Dyson H.J., Wright P.E. Curr. Opin. Struct. Biol. 12:2002;54-60.
29. Dunker A.K., Brown C.J., Lawson D., Iakoucheva L.M., Obradovic Z. Biochemistry. 41:2002;6573-6582.
30. Namba K. Genes Cells. 6:2001;1-12.