The relationship between pneumonia and gastric colonization in surgical intensive-care unit patients

Journal of Applied Research

Volumn 3, Issue 2, 2003, Pages 104-111

  Comert M ^a   Ucan B H ^a   Begendik, F ^b   Oguz M ^c  

^a ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

^b ZONGULDAK KARAELMAS UNIVERSITY   (Turkey)

^c GAZI UNIVERSITY   (Turkey)

Author keywords

Gastrointestinal colonization; Intensive care unit; Nosocomial pneumonia

Indexed keywords

ADULT; AGED; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL PNEUMONIA; FEMALE; HOSPITAL INFECTION; HUMAN; INFECTION RISK; INTESTINE FLORA; MAJOR CLINICAL STUDY; MALE; NOSE FEEDING; POSTOPERATIVE COMPLICATION; RISK ASSESSMENT; SPUTUM CULTURE; STOMACH;

EID: 0141457727     PISSN: 1537064X     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Maki DG: Risk factors for nosocomial infection in intensive care: 'devices vs nature' and goals for the next decade. Arch Intern Med 149:30, 1989.
2. Klein BS, Perloff WH, Maki DG: Reduction of nosocomial infection during pediatric intensive care by protective isolation. N Engl J Med 320: 1714, 1989.
3. Maki DG: Risk factors for nosocomial infections in intensive care units. Intens Care Med 16(suppl 3):S197, 1990.
4. du Moulin GC, Hedley-White J, Paterson DG, et al: Aspiration of gastric bacteria in antiacid-treated patients: a frequent cause of postoperative colonisation of the airway. Lancet 1:242, 1982.
5. Garvey BM, McCambley JA, Tuxen DV: Effects of gastric alkalization on bacterial colonization in critically ill patients. Crit Care Med 17:211, 1989.
6. Marshall JC, Christou NV, Meakins JL: The gastrointestinal tract: the 'undrained abscess' of multiple organ failure. Ann Surg 218:111, 1993.
7. Craven DE, Kunches LM, Lichtenberg DA, et al: Nosocomial infection and fatality in medical and surgical intensive care unit patients. Arch Intern Med 148:1161, 1988.
8. Knaus WA, Draper EA, Wagner DP, et al: APACHE II: a severity of disease classification system. Crit Care Med 13:818, 1985.
9. Cook DJ, Fuller HD, Guyatt GH, et al: Risk factors for gastrointestinal bleeding in critically ill patients. N Engl J Med 330:377, 1994.
10. Gorbach SL, Plaut AG, Nahas L, et al: Studies of intestinal microflora. II. Microorganisms of the small intestine and their relations to oral and fecal flora. Gastroenterol 53:856, 1967.
11. Finegold SM, Sutter VL, Mathisen GE: Normal indigenous intestinal flora. In: Hentges DJ, ed. Human Intestinal Microflora in Health and Disease. New York: Academic Press; 1983:3-31.
12. Lee A: Neglected niches: the microbial ecology of gastrointestinal tract. Adv Microb Ecol 8:115, 1985.
13. Floch MH, Binder HJ, Filburn B, et al: The effect of bile acids on intestinal microflora. Am J Clin Nutr 25:1418, 1972.
14. McLaughlin GA, Hede JE, Temple JG, et al: The role of IgA in the prevention of bacterial colonization of the jejunum in the vagotomized subject. Br J Surg 65:435, 1978.
15. Eisenhauer PB, Harwing SSL, Lehrer RI: Cryptdins: antimicrobial defensins of the murine small intestine. Infect Immunol 60:3556, 1992.
16. Shah PC, Freier S, Park BH, et al: Pancreozymin and secretin enhance duodenal fluid antibody levels to cow's milk proteins. Gastroenterol 83:881, 1982.
17. Moore FA, Feliciano DV, Andrassy RJ, et al: Early enteral feeding, compared with parenteral, reduces postoperative septic complications. Ann Surg 216:172, 1992.
18. Eddleston JM, Vohra A, Scott P, et al: A comparison of the frequency of stress ulceration and secondary pneumonia in sucralfate or ranitidine treated intensive care unit patients. Crit Care Med 19:1491, 1991.
19. Ruddel W, Axon A, Findlay J, et al: Effect of cimetidine on the gastric bacterial flora. Lancet ii:672, 1980.
20. Atherton S, White D: The stomach as a source of bacteria colonising the respiratory tract during artificial ventilation. Lancet ii:968, 1978.
21. Tryba M: Risk of acute stress bleeding and nosocomial pneumonia in ventilated intensive care unit patients: sucralfate versus antacids. Am J Med 22(suppl 140):7, 1987.
22. Blair P, Rowlands BJ, Lowry K, et al: Selective decontamination of the digestive tract: a stratified, randomized, prospective study in a mixed intensive care unit. Surgery 110:303, 1991.
23. Stoutenbeek ChP, van Saene HKF, Miranda DR, et al: The effect of selective decontamination of the digestive tract on colonization and infection rate in multiple trauma patients. Intens Care Med 10:185, 1984.
24. Ledingham IMcA, Alcock SR, Eastaway AT, et al: Triple regimen of selective decontamination of the digestive tract, systemic cefotaxime, and microbiological surveillance for prevention of acquired infection in intensive care. Lancet 1:785, 1988.
25. Gastinne H, Wolff M, Delatour F, et al: A controlled trial in intensive care units of selective decontamination of the digestive tract with non-absorbable antibiotics. N Engl J Med 326:594, 1992.
26. Knaus WA, Draper EA, Wagner DP, et al: An evaluation of outcome from intensive care in major medical centers. Ann Intern Med 104:410, 1986.
27. Driks MR, Craven DE, Celli BR, et al: Nosocomial pneumonia in intubated patients given sucralfate as compared with antacids or histamine type 2 blockers. N Engl J Med 317:1376, 1987.
28. Craven DE, Driks MR: Nosocomial pneumonia in the intubated patient. Semin Respir Infect 2:20, 1987.
29. Kingston GW, Phang PT, Leathley MS: Increased incidence of nosocomial pneumonia in mechanically ventilated patients with subclinical aspiration. Am J Surg 161:585, 1991.