Properties of natural double-strand-break sites at a recombination hotspot in Saccharomyces cerevisiae

Genetics

Volumn 165, Issue 1, 2003, Pages 101-114

  Haring, Stuart J ^a   Halley, George R ^a   Jones, Alex J ^a   Malone, Robert E ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DOUBLE STRANDED DNA;

ARTICLE; BASE PAIRING; CHIRALITY; CHROMOSOME STRUCTURE; COMPETITIVE INHIBITION; DNA RECOMBINATION; DNA SEQUENCE; DNA STRAND BREAKAGE; DNA STRUCTURE; GENE CONSTRUCT; GENE CONVERSION; GENE DELETION; GENE FUNCTION; GENE LOCATION; GENE MAPPING; GENETIC ANALYSIS; GENETIC RECOMBINATION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS; YEAST;

CHROMOSOMES; DIPLOIDY; DNA DAMAGE; RECOMBINATION, GENETIC; SACCHAROMYCES CEREVISIAE; SEQUENCE DELETION;

SACCHAROMYCES; SACCHAROMYCES CEREVISIAE;

EID: 0141455108     PISSN: 00166731     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (42)

1. ALANI, E., R. PADMORE and N. KLECKNER, 1990 Analysis of wild-type and rad50 mutants of yeast suggests an intimate relationship between meiotic chromosome synapsis and recombination. Cell 61: 419-436.
2. BAUDAT, F., and A. NICOLAS, 1997 Clustering of meiotic double-strand breaks on yeast chromosome III. Proc. Natl. Acad. Sci. USA 94: 5213-5218.
3. BOLIVAR, F., R. L. RODRIGUEZ, P. J. GREENE, M. C. BETLACH, H. L. HEYNEKER et al., 1977 Construction and characterization of new cloning vehicles. II. A multipurpose cloning system. Gene 2: 95-113.
4. BORDE, V., T. C. WU and M. LICHTEN, 1999 Use of a recombination reporter insert to define meiotic recombination domains on chromosome III of Saccharomyces cerevisiae. Mol. Cell. Biol. 19: 4832-4842.
5. BULLARD, S. A., S. KIM, A. M. GALBRAITH and R. E. MALONE, 1996 Double strand breaks at the HIS2 recombination hot spot in Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 93: 13054-13059.
6. CAO, L., E. ALANI and N. KLECKNER, 1990 A pathway for generation and processing of double-strand breaks during meiotic recombination in S. cerevisiae. Cell 61: 1089-1101.
7. CHEREST, H., and Y. SURDIN-KERJAN, 1992 Genetic analysis of a new mutation conferring cysteine auxotrophy in Saccharomyces cerevisiae: updating of the sulfur metabolism pathway. Genetics 130: 51-58.
8. DE MASSY, B., and A. NICOLAS, 1993 The control in cis of the position and the amount of the ARG4 meiotic double-strand break of Saccharomyces cerevisiae. EMBO J. 12: 1459-1466.
9. DE MASSY, B., V. ROCCO and A. NICOLAS, 1995 The nucleotide mapping of DNA double-strand breaks at the CYS3 initiation site of meiotic recombination in Saccharomyces cerevisiae. EMBO J. 14: 4589-4598.
10. DETLOFF, P., M. A. WHITE and T. D. PETES, 1992 Analysis of a gene conversion gradient at the HIS4 locus in Saccharomyces cerevisiae. Genetics 132: 113-123.
11. DIAZ, R. L., A. D. ALCID, J. M. BERGER and S. KENNEY, 2002 Identification of residues in yeast Spo11p critical for meiotic DNA double-strand break formation. Mol. Cell. Biol. 22: 1106-1115.
12. FAN, Q., F. XU and T. D. PETES, 1995 Meiosis-specific double-strand DNA breaks at the HIS4 recombination hot spot in the yeast Saccharomyces cerevisiae: control in cis and trans. Mol. Cell. Biol. 15: 1679-1688.
13. FAN, Q. Q., F. XU, M. A. WHITE and T. D. PETES, 1997 Competition between adjacent meiotic recombination hotspots in the yeast Saccharomyces cerevisiae. Genetics 145: 661-670.
14. GAME, J. C., 1992 Pulsed-field gel analysis of the pattern of DNA double-strand breaks in the Saccharomyces genome during meiosis. Dev. Genet. 13: 485-497.
15. GERTON, J. L., J. DERISI, R. SHROFF, M. LICHTEN, P. O. BROWN et al., 2000 Inaugural article: global mapping of meiotic recombination hotspots and coldspots in the yeast Saccharomyces cerevisiae. Proc. Natl. Acad. Sci. USA 97: 11383-11390.
16. GIETZ, R. D., and A. SUGINO, 1988 New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74: 527-534.
17. HO, S. N., H. D. HUNT, R. M. HORTON, J. K. PULLEN and L. R. PEASE, 1989 Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77: 51-59.
18. KEENEY, S., 2001 Mechanism and control of meiotic recombination initiation. Curr. Top. Dev. Biol. 52: 1-53.
19. LICHTEN, M., and A. S. GOLDMAN, 1995 Meiotic recombination hotspots. Annu. Rev. Genet. 29: 423-444.
20. LIU, J., T. C. WU and M. LICHTEN, 1995 The location and structure of double-strand DNA breaks induced during yeast meiosis: evidence for a covalently linked DNA-protein intermediate. EMBO J. 14: 4599-4608.
21. MALONE, R. E., S. BULLARD, S. LUNDQUIST, S. KIM and T. TARKOWSKI, 1992 A meiotic gene conversion gradient opposite to the direction of transcription. Nature 359: 154-155.
22. MALONE, R. E., S. KIM, S. A. BULLARD, S. LUNDQUIST, L. HUTCHINGS-CROW et al., 1994 Analysis of a recombination hotspot for gene conversion occurring at the HIS2 gene of Saccharomyces cerevisiae. Genetics 137: 5-18.
23. MORTIMER, R. K., and S. FOGEL, 1974 Genetical interference and gene conversion, pp. 263-275 in Mechanism in Recombination, edited by R. F. GRELL. Plenum, New York.
24. NAG, D. K., and A. KURST, 1997 A 140-bp-long palindromic sequence induces double-strand breaks during meiosis in the yeast Saccharomyces cerevisiae. Genetics 146: 835-847.
25. NICOLAS, A., D. TRECO, N. P. SCHULTES and J. W. SZOSTAK, 1989 An initiation site for meiotic gene conversion in the yeast Saccharomyces cerevisiae. Nature 338: 35-39.
26. OHTA, K., T. C. WU, M. LICHTEN and T. SHIBATA, 1999 Competitive inactivation of a double-strand DNA break site involves parallel suppression of meiosis-induced changes in chromatin configuration. Nucleic Acids Res. 27: 2175-2180.
27. PAQUES, F., and J. E. HABER, 1999 Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae. Microbiol. Mol. Biol. Rev. 63: 349-404.
28. PECINA, A., K. N. SMITH, C. MEZARD, H. MURAKAMI, K. OHTA et al., 2002 Targeted stimulation of meiotic recombination. Cell 111: 173-184.
29. PETES, T. D., 2001 Meiotic recombination hot spots and cold spots. Nat. Rev. Genet. 2: 360-369.
30. ROSS, L. O., D. TRECO, A. NICOLAS, J. W. SZOSTAK and D. DAWSON, 1992 Meiotic recombination on artificial chromosomes in yeast. Genetics 131: 541-550.
31. ROSS, L. O., D. ZENVIRTH, A. R. JARDIM and D. DAWSON, 2000 Double-strand breaks on artificial chromosomes in yeast. Chromosoma 109: 226-234.
32. ROTHSTEIN, R., 1991 Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast. Methods Enzymol. 194: 281-301.
33. SCHULTES, N. P., and J. W. SZOSTAK, 1990 Decreasing gradients of gene conversion on both sides of the initiation site for meiotic recombination at the ARG4 locus in yeast. Genetics 126: 813-822.
34. SCHWACHA, A., and N. KLECKNER, 1994 Identification of joint molecules that form frequently between homologs but rarely between sister chromatids during yeast meiosis. Cell 76: 51-63.
35. SIKORSKI, R. S., and P. HIETER, 1989 A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 122: 19-27.
36. SOUTHERN, E. M., 1975 Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98: 503-517.
37. SUN, H., D. TRECO, N. P. SCHULTES and J. W. SZOSTAK, 1989 Double-strand breaks at an initiation site for meiotic gene conversion. Nature 338: 87-90.
38. SUN, H., D. DAWSON and J. W. SZOSTAK, 1991 Genetic and physical analyses of sister chromatid exchange in yeast meiosis. Mol. Cell. Biol. 11: 6328-6336.
39. VEDEL, M., and A. NICOLAS, 1999 CYS3, a hotspot of meiotic recombination in Saccharomyces cerevisiae: effects of heterozygosity and mismatch repair functions on gene conversion and recombination intermediates. Genetics 151: 1245-1259.
40. WHITE, M. A., M. WIERDL, P. DETLOFF and T. D. PETES, 1991 DNA-binding protein RAP1 stimulates meiotic recombination at the HIS4 locus in yeast. Proc. Natl. Acad. Sci. USA 88: 9755-9759.
41. WU, T. C., and M. LICHTEN, 1995 Factors that affect the location and frequency of meiosis-induced double-strand breaks in Saccharomyces cerevisiae. Genetics 140: 55-66.
42. XU, L., and N. KLECKNER, 1995 Sequence non-specific double-strand breaks and interhomolog interactions prior to double-strand break formation at a meiotic recombination hot spot in yeast. EMBO J. 14: 5115-5128.