Lack of clastogenic effects in cultured human lymphocytes treated with hydroquinone

Food and Chemical Toxicology

Volumn 41, Issue 10, 2003, Pages 1299-1305

  Roza, L ^a   De Vogel, N ^a   Van Delft, J H M ^a,b  

^a TNO   (Netherlands)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Antimutagen; Clastogenicity; Human lymphocytes; Hydroquinone; Mutagenicity

Indexed keywords

HYDROGEN PEROXIDE; HYDROQUINONE; HYDROQUINONE DERIVATIVE; MUTAGENIC AGENT; OXIDIZING AGENT;

ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; GENOTOXICITY; HUMAN; HUMAN CELL; LYMPHOCYTE CULTURE; MALE; METABOLIC ACTIVATION; MUTAGENICITY; NORMAL HUMAN; STRUCTURAL CHROMOSOME ABERRATION; ANIMAL; BIOTRANSFORMATION; CELL CULTURE; CHROMATID; CHROMOSOME ABERRATION; DRUG EFFECT; IN VITRO STUDY; LIVER; LYMPHOCYTE; METABOLISM; MUTAGEN TESTING; RAT; WISTAR RAT;

ANIMALIA;

ANIMALS; BIOTRANSFORMATION; CELLS, CULTURED; CHROMATIDS; CHROMOSOME ABERRATIONS; HUMANS; HYDROGEN PEROXIDE; HYDROQUINONES; LIVER; LYMPHOCYTES; MALE; MUTAGENICITY TESTS; MUTAGENS; OXIDANTS; RATS; RATS, WISTAR;

EID: 0141432150     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(03)00118-2     Document Type: Article

References (39)

1. Ames B.N., McCann J., Yamasaki E. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test. Mutation Res. 31:1975;347-365.
2. Andreoli C., Rossi S., Leopardi P., Crebelli R. DNA damage by hydoquinone in human white blood cells. analysis by alkaline single-cell electrophoresis Mutation Res. 438:1999;37-45.
3. Boatman R.J., English J.C., Perry L.G., Fiorica L.A. Covalent protein adducts of hydroquinone in tissues from rats. identification and quantitation of sulfhydryl-bound forms Chem. Res. Toxicol. 13:2000;853-860.
4. Chen H.W., Tomar R., Eastmond D.A. Detection of hydroquinone-induced nonrandom breakage in the centromeric heterochromatin of mouse bone marrow cells using multicolor fluorescence in situ hybridization with the mouse major and minor satellite probes. Mutagenesis. 9:1994;563-569.
5. Ciranni R., Barale R., Ghelardini G., Loprieno N. Benzene and the genotoxicity of its metabolites. II. The effect of the route of administration on the micronuclei and bone marrow depression in mouse bone marrow cells. Mutation Res. 209:1988;23-28.
6. Clifford A.J., Ebeler S.E., Bills N.D., Hinrichs S.H., Teissedre P.-L., Waterhouse A.L. Delayed tumor onset in transgenic mice fed an amino-acid diet supplemented with red wine solids. Am. J. Clin. Nutr. 64:1996;748-756.
7. DeCaprio A.P. The toxicology of hydroquinone - relevance to occupational and environmental exposure. Critical reviews in toxicology. 29:1999;282-330.
8. Deisinger P.J., Hill T.S., English J.C. Human exposure to naturally occurring hydroquinone. Journal Toxicological and Environmental Health. 47:1996;101-116.
9. Doepker C.L., Dumont K.W., O'Donoghue J., English J.C. Lack of induction of micronuclei in human peripheral blood lymphocytes treated with hydroquinone. Mutagenesis. 15:2000;479-487.
10. Eastmond D.A., Rupa D.S., Hasegawa L.S. Detection of hyperploidy and chromosome breakage in interphase human lymphocytes following exposure to the benzene metabolite hydroquinone using multicolor fluorescence in situ hybridization with DNA probes. Mutation Res. 322:1994;9-20.
11. Mutagenicity: In vitro mammalian cytogenetic test, Protocol B. 10 of EEC Council Directive 67/548; seventeenth amendment; annex V, part B. Official Journal of the European Community, L 383A. 35:1992;148-150.
12. Erexson G.L., Wilmer J.L., Kligerman A.D. Sister chromatid exchange induction in human lymphocytes exposed to benzene and its metabolites in vitro. Cancer Res. 45:1985;2471-2477.
13. Fabiani R., De-Bartolomeo A., Rosignoli P., Scamosci M., Lepore L., Morozzi G. Influence of culture conditions on the DNA-damaging effect of benzene and its metabolites in human peripheral blood mononuclear cells. Environ. Mol. Mutagen. 37:2001;1-6.
14. Ferguson L.R., Morcombe P., Triggs C.N. The size of cytokinesis-blocked micronuclei in human peripheral blood lymphocytes as a measure of aneuploidy induction by Set A compounds in the EEC trial. Mutation Research. 287:1993;101-112.
15. Glatt H., Padykula R., Berchtold G.A., Ludewig G., Platt K.L., Klein J., Oesch F. Multiple activation pathways of benzene leading to products with varying genotoxic characteristics. Environmental Health Perspectives. 82:1989;81-89.
16. van Hummelen P., Kirsch-Volders M. Discrimination of aneuploidogens from clastogens by C-banding, DNA and area measurements of micronuclei from mouse bone marrow. Mutation Res. 271:1992;57-70.
17. Hoffmann D., Wynder E.L. Chemical constituents and bioactivity of tobacco. IARC Scientific Publications. 74:1986;145-165.
18. Overall evaluations of carcinogenicity: an updating of IARC monographs 1 to 42. Lyon. Suppl. 7:1987;120-122.
19. Knadle S. Synergistic interaction between hydroquinone and acetaldehyde in the induction of sister chromatid exchange in human lymphocytes in vitro. Cancer Res. 45:1985;4853-4857.
20. Malaveille C., Hautefeuille A., Pignatelli B., Talaska G., Vineis P., Bartsch H. Dietary phenolics as antimutagens and inhibitors of tobacco-related DNA adduction in the urothelium of smokers. Carcinogenesis. 17:1996;2193-2200.
21. Maron D.M., Ames B.N. Revised methods for the Salmonella mutagenicity test. Mutation Res. 113:1983;173-215.
22. Migliori L., Nieri M. Evaluation of twelve potential aneupoidogenic chemicals by the in vitro human lymphocyte micronucleus assay. Toxicology in vitro. 5:1991;325-336.
23. National Toxicology Program, 1989. Toxicology and Carcinogenesis Studies of Hydroquinone in F-344/N Rats and B6C3F1 Mice. NIH Publication No. 90-2821, Research Triangle Park, NC, USA.
24. Genetic Toxicology: In Vitro Mammalian Chromosome Aberration Test. OECD Guidelines for the Testing of Chemicals, no. 473. 1997;Organization for Economic Co-Operation and Development, Paris.
25. O'Donoghue J., Barber E.D., Hill T., Aebi J., Fiorica L. Hydroquinone. Genotoxicity and prevention of genotoxicity following ingestion Food and Chemical Toxicology. 37:1999;931-936.
26. Pifer J.W., Hearne F.T., Swanson F.A., O'Donoghue J.L. Mortality study of employees engaged in the manufacture and use of hydroquinone. International Archives of Occupational and Environmental Health. 67:1995;267-289.
27. Robertson M.L., Eastmond D.A., Smith M.T. Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes. Mutation Res. 249:1991;201-209.
28. Rupa D.S., Schuler M., Eastmond D.A. Detection of hyperploidy and breakage affecting the 1cen-1q12 region of cultured interphase human lymphocytes treated with various genotoxic agent. Environ. Mol. Mutagen. 29:1997;161-167.
29. Rutten A.A.J.J.L., Falke H.E., Catsburg J.F., Topp R., Blaauboer B.J., van Holstein I., Doorn L., van Leeuwen F.X.R. Interlaboratory comparison of total cytochrome P-450 and protein determination in rat liver microsomes. Reinvestigation of assay conditions. Arch. Toxicol. 61:1987;27-33.
30. Savage J. Annotation. classification and relationships of induced chromosome structural change Journal of Medical Genetics. 13:1975;103-122.
31. Shibata M.-A., Hirose M., Tanaka H., Asakawa E., Shirai T., Nobuyuki I. Induction of renal cell tumors in rats and mice, enhancement of hepatocellular tumor development in mice after long-term hydroquinone treatment. Japanese Journal of Cancer Research. 82:1991;1211-1219.
32. Smith M.T., Zhang L., Jeng M., Wang Y., Guo W., Duramad P., Hubbard A.E., Hofstadler G., Holland N.T. Hydroquinone, a benzene metabolite, increases the level of chromosomes 7 and 8 in human CD34-positive blood progenitor cells. Carcinogenesis. 21:2000;1485-1490.
33. Soucek P., Ivan G., Pavel S. Effect of the microsomal system on interconversions between hydroquinone, benzoquinone, oxygen activation, and lipid peroxidation. Chem-Biol-Interact. 126:2000;45-61.
34. Talalay P., Fahey J.W., Holtzclaw W.D., Prestera T., Zhang Y. Chemoprotection against cancer by phase 2 enzyme induction. Toxicology Letters. 82/83:1995;173-179.
35. USA-EPA Health Effects Testing Guidelines, 1989. 40 CFR Ch. 1 (7-1-89 Edition) § 798.5375, The USA Environmental Protection Agency (EPA), pp. 506-509.
36. Vian L., van Hummelen P., Bichet N., Gouy D., Kirsch-Volders M. Evaluation of hydroquinone and chloral hydrate on the in vitro micronucleus test on isolated lymphocytes. Mutation Res. 334:1995;1-7.
37. Whysner J., Verna L., English J.C., Williams G.M. Analysis of studies related to tumorgenicity induced by hydroquinone. Regulatory Toxicology and Pharmacology. 21:1995;158-176.
38. Yager J.W., Eastmond D.A., Robertson M.L., Paradisi W.M., Smith M.T. Characterization of micronuclei in induced human lymphocytes by benzene metabolites. Cancer Res. 90:1990;393-399.
39. Zhang L.-S., Honma M., Sofuni T., Matsuoka A., Suzuki T., Hayashi M. The induction of micronuclei and gene mutations in L5178Y mouse lymphoma cells by hydroquinone and diethylstilbestrol. a comparison of short- and low-term treatments MMS Communications. 4:1996;113-120.