Enantioselective synthesis of protoberberine alkaloids via (-)-sparteine-mediated asymmetric condensation-cyclisation of o-toluamide anions with 3,4-dihydroisoquinolines

Synthesis

Volumn , Issue 11, 2003, Pages 1705-1706

  Liu, Ligong ^a  

^a Progen Pharmaceuticals Limited   (Australia)

Author keywords

( ) sparteine; 3,4 dihydroisoquinoline; Anion addition; Asymmetric synthesis; Protoberberine

Indexed keywords

ADDITION REACTIONS; CONDENSATION; NEGATIVE IONS; SYNTHESIS (CHEMICAL);

METALATIONS;

ORGANIC COMPOUNDS;

2 TOLUAMIDE; 3,4 DIHYDROISOQUINOLINE DERIVATIVE; 8 OXOPROTOBERBERINE; ALKALOID; AMIDE; ANION; ISOQUINOLINE DERIVATIVE; LIGAND; PROTOBERBERINE; SPARTEINE; UNCLASSIFIED DRUG;

ADDITION REACTION; ARTICLE; CYCLIZATION; ENANTIOSELECTIVITY; POLYMERIZATION; SYNTHESIS;

EID: 0043240466     PISSN: 00397881     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-40886     Document Type: Article

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