Lipid peroxidation and antioxidant systems in the blood of young rats subjected to chronic fluoride toxicity

Indian Journal of Experimental Biology

Volumn 41, Issue 8, 2003, Pages 857-860

  Shivarajashankara, Y M ^a   Shivashankara, A R ^a   Gopalakrishna Bhat, P ^b   Hanumanth Rao, S ^c  

^a M R MEDICAL COLLEGE   (India)

^b KASTURBA MEDICAL COLLEGE   (India)

^c KBN Institute of Medical Sciences   (India)

Author keywords

Antioxidant system; Fluoride in water; Fluoride toxicity; Lipid peroxidation

Indexed keywords

ANTIOXIDANTS; BLOOD; FLUORINE COMPOUNDS; TOXICITY;

PATHOGENESIS;

LIPIDS;

ASCORBIC ACID; FLUORIDE SODIUM; GLUTATHIONE; MALONALDEHYDE; SUPEROXIDE DISMUTASE; URIC ACID;

ANIMAL; ARTICLE; BLOOD; DOSE RESPONSE; DRUG EFFECT; ENZYMOLOGY; ERYTHROCYTE; FEMALE; LIPID PEROXIDATION; METABOLISM; ORAL DRUG ADMINISTRATION; PREGNANCY; PRENATAL EXPOSURE; RAT; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; ASCORBIC ACID; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTES; FEMALE; GLUTATHIONE; LIPID PEROXIDATION; MALONDIALDEHYDE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, WISTAR; SODIUM FLUORIDE; SUPEROXIDE DISMUTASE; URIC ACID;

ANIMALIA;

EID: 0043199590     PISSN: 00195189     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (28)

1. Anasuya Das A, Fluorosis, in Text book of human nutrition, edited by M S Bamji, N P Rao & V Reddy (Oxford and IBH Publishing Co., New Delhi) 1996, 424.
2. Krishnamachari K A V R, Fluoride, in Trace elements in human nutrition and health (WHO, Geneva) 1996, 189.
3. Monsaur P A & Kruger B J, Effect of fluoride on soft tissues in vertebrates, Fluoride, 18 (1985) 53.
4. Zhavoronkov A A, Non-skeletal forms of fluorosis, Arch Pathol, 39 (1977) 83.
5. Shivarajashankara Y M, Shivashankara A R, Gopalakrishna Bhat P, Muddanna Rao S & Hanumanth Rao S, Histological changes in the brain of young fluoride intoxicated rats, Fluoride, 35 (2002) 12.
6. Singh M, Biochemical and cytochemical alterations in liver and kidney following experimental fluorosis, Fluoride, 17 (1984) 81.
7. Vani M L & Reddy K P, Effects of fluoride accumulation on some enzymes of brain and gastrocnemius muscle of mice, Fluoride, 33 (2000) 17.
8. Halliwell B & Gutteridge J M C, Oxygen radicals and the nervous system, Trends Neurosci, 8 (1985) 22.
9. Saralakumari D & Ramakrishna Rao P, Red cell membrane alterations in human chronic fluoride toxicity, Biochem Int, 23 (1991) 639.
10. Shivarajashankara Y M, Shivashankara A R, Hanumanth Rao S & Gopalakrishna Bhat S, Oxidative stress in children with endemic skeletal fluorosis, Fluoride, 34 (2001) 103.
11. Patel D & Chinoy N J, Influence of fluoride on biological free radical reactions in ovary of mice and its reversal, Fluoride, 31 (1998) S27.
12. Sharma A & Chinoy N J, Role of free radicals in fluoride-induced toxicity in liver and kidney of mice and its reversal, Fluoride, 31 (1998) S26.
13. Shivarajashankara Y M, Shivashankara A R, Hanumanth Rao S & Gopalakrishna Bhat S, Effect of fluoride intoxication on lipid peroxidation and antioxidant systems in rats, Fluoride, 34 (2001) 108.
14. Ohkawa H, Ohishi N & Yagi K, Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction, Anal Biochem, 95 (1979) 351.
15. Akerboom T P M & Sies H, Assay of glutathione, glutathione disulfide and glutathione mixed disulfides in biological samples, in Methods in enzymology, Vol. 77, edited by WB Jakoby (Academic Press, New York) 1981, 373.
16. Beautler E, Duron O & Kelly B M, Improved methods for the determination of blood glutathione, J Lab Clin Med, 61 (1963) 882.
17. Pagila D E & Valentine W N, Studies on the quantitative and qualitative characterization of erythrocyte glutathione peroxidase, J Lab Clin Med, 70 (1967) 158.
18. Beauchamp C & Fridovich I, Superoxide dismutase: improved assays and an assay applicable to acrylamide gel, Anal Biochem, 44 (1971) 276.
19. th edition, edited by AH Gowenlock (Heinemann, London) 1988, 664.
20. McCormick D B & Greene H L, Methods for determination of ascorbic acid, in Tietz text book of clinical chemistry, second edition, edited by CA Burtis & ER Ashwood (WB Saunders, Philadelphia) 1994, 1313.
21. Trivedi R C, Rebar L, Berta E & Stong L, New enzymatic method for serum uric acid at 500 nm, Clin Chem, 24 (1978) 1908.
22. Stern A, Red cell oxidative damage, in Oxidative stress, edited by H Sies (Academic Press, New York) 1985, 331.
23. Chow C K & Tappel A L, An enzymatic protective mechanism against lipid peroxidation damage to lungs of ozone exposed rats, Lipids, 7 (1972) 518.
24. Edes I, Piros G, Toth G K, Csanady M & Kovacs K, Effects of long-term alcohol ingestion on glutathione metabolising enzymes and taurine contents in the myocardium of rats, Cardiovasc Res, 20 (1986) 918.
25. Frei B, England L & Ames B N, Ascorbate is an outstanding antioxidant in human blood plasma, Proc Natl Acad Sci, 86 (1989) 6377.
26. Jacob R A & Buri R J, Oxidative damage and defense, Am J clin Nutr, 63 (1996) 985S.
27. Chinoy N J, Metabolic significance of ascorbic acid in animal and human tissues, J Animal Morphol Physiol, Silver jubilee commemorative vol (1978) 68.
28. Chinoy N J, Sharma M & Michael M, Beneficial effects of ascorbic acid and calcium on reversal of fluoride toxicity in male rats, Fluoride, 26 (1993) 45.