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Structure of the cell-puncturing device of bacteriophage T4
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Mol Microbiol
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Ferretti JJ, McShan WM, Ajdic D, Savic DJ, Savic G, Lyon K, Primeaux C, Sezate S, Suvorov AN, Kenton S et al.: Complete genome sequence of an M1 strain of Streptococcus pyogenes. Proc Natl Acad Sci USA 2001, 98:4658-4663.
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Beres SB, Sylva GL, Barbian KD, Lei B, Hoff JS, Mammarella ND, Liu MY, Smoot JC, Porcella SF, Parkins LD et al.: Genome sequence of a serotype M3 strain of group A Streptococcus: phage-encoded toxins, the high-virulence phenotype, and clone emergence. Proc Natl Acad Sci USA 2002, 99:10078-10083. Strains carrying two important phage-encoded virulence factors increased dramatically in frequency in the late 20th century. The analysis presented in this thrilling paper suggests that the sequential acquisition of three prophages carrying toxin, superantigen and phospholipase genes has played a critical role in the emergence of a new and unusually virulent Streptococcus pyogenes clone in the 1980s.
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Proc Natl Acad Sci USA
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0037007095
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Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks
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Smoot JC, Barbian KD, Van Gompel JJ, Smoot LM, Chaussee MS, Sylva GL, Sturdevant DE, Ricklefs SM, Porcella SF, Parkins LD et al.: Genome sequence and comparative microarray analysis of serotype M18 group A Streptococcus strains associated with acute rheumatic fever outbreaks. Proc Natl Acad Sci USA 2002, 99:4668-4673. Phage, phage-like elements and insertion sequences were the major sources of variation between the genomes from Streptococcus pyogenes strains involved in two distinct pathologies, wound infections and rheumatic fever. The prophages encode several secreted proteins involved in human-bacterium interaction, including the scarlet fever toxin. Phage DNA also represents the major source of genetic variability between S. pyogenes isolates belonging to the same M type.
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Proc Natl Acad Sci USA
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Smoot, J.C.1
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Ricklefs, S.M.8
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0036434356
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Transcription analysis of Streptococcus thermophilus phages in the lysogenic state
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Complete genomic sequence of SfV, a serotype-converting temperate bacteriophage of Shigella flexneri
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Allison GE, Angeles D, Tran-Dinh N, Verma NK: Complete genomic sequence of SfV, a serotype-converting temperate bacteriophage of Shigella flexneri. J Bacteriol 2002, 184:1974-1987. Phages act as the vector for lateral gene transfer between bacterial genomes, in this case of O-serotype modifying enzymes. Horizontal gene transfer also occurs between two or more phages as demonstrated by a chimeric prophage genome combining structural genes from two different families of tailed phages, Siphoviridae and Myoviridae.
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Trends Microbiol
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Brüssow, H.2
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Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli
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Wagner PL, Livny J, Neely MN, Acheson DW, Friedman DI, Waldor MK: Bacteriophage control of Shiga toxin 1 production and release by Escherichia coli. Mol Microbiol 2002, 44:957-970.
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Mol Microbiol
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Wagner, P.L.1
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Role for a phage promoter in Shiga toxin 2 expression from a pathogenic Escherichia coli strain
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Wagner PL, Neely MN, Zhang X, Acheson DW, Waldor MK, Friedman DI: Role for a phage promoter in Shiga toxin 2 expression from a pathogenic Escherichia coli strain. J Bacteriol 2001, 183:2081-2085.
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J Bacteriol
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Wagner, P.L.1
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21
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Induction of lysogenic bacteriophage and phage-associated toxin from group A streptococci during coculture with human pharyngeal cells
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Broudy TB, Pancholi V, Fischetti VA: Induction of lysogenic bacteriophage and phage-associated toxin from group A streptococci during coculture with human pharyngeal cells. Infect Immun 2001, 69:1440-1443.
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Human neutrophils and their products induce Shiga toxin production by enterohemorrhagic Escherichia coli
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Wagner PL, Acheson DW, Waldor MK: Human neutrophils and their products induce Shiga toxin production by enterohemorrhagic Escherichia coli. Infect Immun 2001, 69:1934-1937.
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Infect Immun
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Global differential gene expression in response to growth temperature alteration in group A Streptococcus
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Smoot LM, Smoot JC, Graham MR, Somerville GA, Sturdevant DE, Migliaccio CA, Sylva GL, Musser JM: Global differential gene expression in response to growth temperature alteration in group A Streptococcus. Proc Natl Acad Sci USA 2001, 98:10416-10421.
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Identification of pathogen-specific and conserved genes expressed in vivo by an avian pathogenic Escherichia coli strain
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Appl Environ Microbiol
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Canchaya C, Proux C, Fournous G, Bruttin A, Brüssow H: Prophage genomics. Microbiol Mol Biol Rev 2003, 67:238-276. The review provides a theoretical framework for the genome interaction between phages and their host-bacteria and presents a comprehensive database mining for prophage sequences encountered in the published bacterial genomes.
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Microbiol Mol Biol Rev
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Trends Microbiol
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Trends Microbiol
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Virology
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J Bacteriol
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Comparative analyses of the complete genome sequences of Pierce's disease and citrus variegated chlorosis strains of Xylella fastidiosa
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Van Sluys MA, de Oliveira MC, Monteiro-Vitorello CB, Miyaki CY, Furlan LR, Camargo LE, da Silva AC, Moon DH, Takita MA, Lemos EG et al.: Comparative analyses of the complete genome sequences of Pierce's disease and citrus variegated chlorosis strains of Xylella fastidiosa. J Bacteriol 2003, 185:1018-1026. Two strains of Xylella fastidiosa, which are linked to different plant pathologies, share 98% of their genes. Genomic differences are limited to phage-associated genome rearrangements and deletions. Prophages also accounted for a substantial part of the strain-specific DNA. There is now increasing evidence (e.g. with the two M3 S. pyogenes strains) that prophages affect the overall chromosomal architecture of bacterial chromosomes and so are subsequently more flexible than anticipated.
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J Bacteriol
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