Specific endothelial binding and tumor uptake of radiolabeled angiostatin

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 30, Issue 7, 2003, Pages 1032-1037

  Lee, Kyung Han ^a   Song, Sung Hee ^a   Paik, Jin Young ^a   Byun, Sang Sung ^a   Lee, Sang Yoon ^a   Choe, Yearn Seong ^a   Kim, Byung Tae ^a  

^a Sungkyunkwan University School of Medicine   (South Korea)

Author keywords

Angiogenesis; Angiostatin; Radioiodine; Tumor

Indexed keywords

ANGIOSTATIN; IODINE 125; LACTOPEROXIDASE; TRACER;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLADDER CANCER; CELL PROLIFERATION; COLON CANCER; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DRUG DEGRADATION; DRUG DISTRIBUTION; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; ISOTOPE LABELING; MALE; MOUSE; NONHUMAN; NUDE MOUSE; RAT; SCINTISCANNING; TUMOR DIAGNOSIS; URINARY EXCRETION;

ANGIOSTATINS; ANIMALS; CELL LINE; CELL LINE, TUMOR; COLONIC NEOPLASMS; ENDOTHELIUM, VASCULAR; FEASIBILITY STUDIES; HUMANS; IODINE RADIOISOTOPES; ISOTOPE LABELING; MALE; METABOLIC CLEARANCE RATE; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASM TRANSPLANTATION; PROTEIN BINDING; RADIOISOTOPE DILUTION TECHNIQUE; RADIOPHARMACEUTICALS; TISSUE DISTRIBUTION;

EID: 0043194283     PISSN: 16197070     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00259-002-1094-9     Document Type: Article

References (19)

1. Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000; 407:249-257.
2. Harris AL. Antiangiogenesis for cancer therapy. Lancet 1997; 349:SII13-SII15.
3. Weidner N, Folkman J, Pozza F, Bevilacqua P, Allred EN, Moore DH, Meli S, Gasparini G. Tumor angiogenesis: a new significant and independent prognostic indicator in early-stage breast carcinoma. J Natl Cancer Inst 1992; 84:1875-1887.
4. Weidner N, Semple JP, Welch WR. Folkman J. Tumor angiogenesis and metastasis: correlation in invasive breast carcinoma. N Engl J Med 1991; 324:1-8.
5. Giatromanolaki A, Stathopoulos GP, Tsiobanou E, Papadimitriou C, Georgoulias V, Gatter KC, Harris AL, Koukourakis MI. Combined role of tumor angiogenesis, bcl-2, and p53 expression in the prognosis of patients with colorectal carcinoma. Cancer 1999; 86:1421-1430.
6. Weber WA, Haubner R, Vabuliene E, Kuhnast B, Wester HJ, Schwaiger M. Tumor angiogenesis targeting using imaging agents. Q J Nucl Med 2001; 45:179-182.
7. Folkman J, Beckner K. Angiogenesis Imaging. Acad Radiol 2000; 7:783-785.
8. Li WW. Tumor angiogenesis: Molecular pathology, therapeutic targeting, and imaging. Acad Radiol 2000; 7:800-811.
9. Jain RK. Delivery of molecular and cellular medicine to solid tumors. Microcirculation 1997; 618:367-382.
10. Boehm T, Folkman J, Browder T, O'Reilly MS. Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance. Nature 1997; 390:404-407.
11. O'Reilly MS, Holmgren L, Chen C, Folkman J. Angiostatin induces and sustains dormancy of human primary tumors in mice. Nat Med 1996; 2:689-692.
12. Vale RD, Shooter EM. Assaying binding of nerve growth factor to cell surface receptors. Methods Enzymol 1985; 109:21-39.
13. Moser TL, Kenan DJ, Ashley TA, Roy JA, Goodman MD, Misra UK, Cheek DJ, Pizzo SV. Endothelial cell surface F1-FO ATP synthase is active in ATP synthesis and is inhibited by angiostatin. Proc Natl Acad Sci USA 2001; 98:6656-6661.
14. Moser TL, Stack MS, Asplin I, Enghild JJ, Hojrup P, Everitt L, Hubchak S, Schnaper HW, Pizzo SV. Angiostatin binds ATP synthase on the surface of human endothelial cells. Proc Natl Acad Sci USA 1999; 96:2811-2816.
15. Tarui T, Miles LA, Takada Y. Specific interaction of angiostatin with integrin αvβ3 in endothelial cells. J Biol Chem 2001; 276:39562-39568.
16. 99mTc-EC-endostatin. Cancer Biother Radiopharm 2002; 17:233-245.
17. Molema G, van Veen-Hof I, van Loenen-Weemaes AM, Proost JH, de Leij LF, Meijer DK. Pharmacokinetics and whole body distribution of elastase derived angiostatin (K1-3) in rats. Int J Cancer 2001; 91:1-7.
18. Rennen HJ, Makarewicz J, Oyen WJ, Laverman P, Corstens FH, Boerman OC. The effect of molecular weight on nonspecific accumulation of (99m)T-labeled proteins in inflammatory foci. Nucl Med Biol 2001; 28:401-408.
19. Ji WR, Castellino FJ, Chang Y, Deford ME, Gray H, Villarreal X, Kondri ME, Marti DN, Llinas M, Schaller J, Kramer RA, Trail PA. Characterization of kringle domains of angiostatin as antagonists of endothelial cell migration, an important process in angiogenesis. FASEB J 1998; 12:1731-1738.