Combined use of clinical assessment and D-dimer to improve the management of patients presenting to the emergency department with suspected deep vein thrombosis (the EDITED Study)

Journal of Thrombosis and Haemostasis

Volumn 1, Issue 4, 2003, Pages 645-651

  Anderson, D R ^a   Kovacs, M J ^d   Kovacs, G ^a   Shell, I ^b   Mitchell, M ^a   Khoury, V ^a   Dryer, J ^d   Ward, J ^e   Wells, P S ^c  

^a DALHOUSIE UNIVERSITY   (Canada)

^b UNIVERSITY OF OTTAWA   (Canada)

^c UNIVERSITY OF OTTAWA   (Canada)

^d UNIVERSITY OF WESTERN ONTARIO   (Canada)

^e UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Clinical probability; D dimer; Deep vein thrombosis; Ultrasonography

Indexed keywords

FIBRIN DEGRADATION PRODUCT; FIBRIN FRAGMENT D;

ADULT; AGED; ALGORITHM; ARTICLE; CLINICAL TRIAL; DISEASE MANAGEMENT; ECHOGRAPHY; EMERGENCY HEALTH SERVICE; FEMALE; FOLLOW UP; HUMAN; MALE; MIDDLE AGED; MULTICENTER STUDY; PREDICTION AND FORECASTING; PROBABILITY; RISK ASSESSMENT; VEIN THROMBOSIS;

ADULT; AGED; ALGORITHMS; DISEASE MANAGEMENT; EMERGENCY MEDICAL SERVICES; FEMALE; FIBRIN FIBRINOGEN DEGRADATION PRODUCTS; FOLLOW-UP STUDIES; HUMANS; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROBABILITY; RISK ASSESSMENT; ULTRASONOGRAPHY; VENOUS THROMBOSIS;

EID: 0043180566     PISSN: 15387933     EISSN: 15387836     Source Type: Journal    
DOI: 10.1046/j.1538-7836.2003.00131.x     Document Type: Article

References (16)

1. Anderson FA, Wheeler HB, Goldberg RJ, Hosmer DW, Patwardhan NA, Jovanovic B, Fourcier A, Dalen JE. A population-based perspective of the hospital incidence and case-fatality rates of deep vein thrombosis and pulmonary embolism. Arch Intern Med 1991; 151: 933-8.
2. Lensing AWA, Prandoni P, Prins MH, Buller HR. Deep-vein thrombosis. Lancet 1999; 353: 479-86.
3. Anderson DR, Wells PS, Stiell I, MacLeod B, Simms M, Gray L, Robinson SK, Bromanis J, Mitchell MJ, Lewandowski B, Flowerdew G. Use of a clinical model to safely avoid the need for urgent radiologic investigation. Arch Intern Med 1999; 159: 477-82.
4. Wells PS, Brill-Edwards P, Stevens P, Panju A, Patel A, Douketis J. A novel and rapid whole-blood assay for D-dimer in patients with clinically suspected deep vein thrombosis. Circulation 1995; 91: 2184-7.
5. Ginsberg JS, Kearon C, Douketis J, Turpie AGG, Brill-Edwards P, Stevens P. The use of D-dimer testing and impedance plethysmographic examination in patients with clinical indications of deep vein thrombosis. Arch Intern Med 1997; 157: 1077-81.
6. Wells PS, Anderson DR, Bormanis J, Guy F, Mitchell M, Lewandoeski B. SimpliRED D-dimer can reduce the diagnostic tests in suspected deep vein thrombosis. Lancet 1998; 351: 1405-6.
7. Wells PS, Hirsh J, Anderson DR, Lensing AW, Foster G, Kearon C, Weitz J, D'Ovidio R, Cogo A, Prandoni P. Accuracy of clinical assessment of deep-vein thrombosis. Lancet 1995; 345: 1326-30.
8. Kovacs MJ, MacKinnon K, Anderson D, O'Rourke K, Keeney M, Kearon C, Ginsberg J, Wells PS. A comparison of three rapid D-dimer methods for the diagnosis of venous thromboembolism. Br J Haematol 2001; 115: 140-4.
9. Lensing WAA, Prandoni P. Detection of deep-vein thrombosis by real-time B-mode ultrasonography. N Engl J Med 1989; 320: 342-5.
10. Anderson DR, Levine MN, Gent M, Hirsh J. Validation of a new criterion for the evaluation of bleeding during antithrombotic therapy. Thromb Haemost 1993; 69: 650.
11. Rabinov K, Paulin S. Roentgen diagnosis of venous thrombosis in the leg. Arch Surg 1972; 104: 134-44.
12. Kearon C, Julian JA, Newman TE, Ginsberg JS. Noninvasive diagnosis of deep vein thrombosis. Ann Intern Med 1998; 128: 663-77.
13. Cogo A, Lensing AWA, Koopman MMW, Piovella F, Siragusa S, Wells PS, Villalta S, Buller HR, Turpie AC, Prandoni P. Compression ultrasonography for diagnostic management of patients with clinically suspected deep vein thrombosis: prospective cohort study. Br Med J 1998; 316: 17-20.
14. Birdwell BC, Raskob GE, Whitsett TL, Durica SS, Comp PC, George JN, Tytle TL, McKee PA. The clinical validity of normal compression ultrasonography in outpatients suspected of having deep venous thrombosis. Ann Intern Med 1998; 128: 1-7.
15. Perrier A, Desmarais S, Miron MJ, de Moerloose P, Lepage R, Slosman D, Didier D, Unger PF, Patenaude JV, Bounameaux H. Non-invasive diagnosis of venous thromboembolism in outpatients. Lancet 1999; 353: 190-5.
16. Kraaijenhagen RA, Lijmer JG, Bossuyt PMM, Prins PMM, Heister-kamp SH, Buller HR. The accuracy of D-dimer in the diagnosis of venous thromboembolism: a meta-analysis. In Kraaijenhagen RA (ed.). The Etiology, Diagnosis and Treatment of Venous Thromboembolism. The Netherlands 2000: 159-83.