Immunomapping of EBA sera to multiple epitopes on collagen VII: Further evidence that anchoring fibrils originate and terminate in the lamina densa

Experimental Dermatology

Volumn 12, Issue 3, 2003, Pages 261-267

  McMillan, James R ^a   Matsumura, Tetsuri ^a   Hashimoto, Takahashi ^b   Schumann, Hans ^c   Bruckner Tuderman, Leena ^c   Shimizu, Hiroshi ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c UNIVERSITY OF MÜNSTER   (Germany)

Author keywords

Autoantibody; Basement membrane; Bullous disease; Immunoelectron microscopy

Indexed keywords

AUTOANTIBODY; COLLAGEN ANTIBODY; COLLAGEN TYPE 7; HYBRID PROTEIN; METHYLPREDNISOLONE; MINOCYCLINE; NICOTINAMIDE; NONCOLLAGENOUS DOMAIN FUSION PROTEIN 1; PREDNISOLONE; STEROID; UNCLASSIFIED DRUG;

ADULT; AGED; ANCHORING FIBRIL; ANTIBODY COMBINING SITE; ANTIGEN BINDING; ARTICLE; AUTOIMMUNE DISEASE; BASEMENT MEMBRANE; BLISTER; CASE REPORT; CELL ORGANELLE; CHEMISTRY; COMPARATIVE STUDY; CONTROLLED STUDY; DERMOEPIDERMAL JUNCTION; EPIDERMIS; EPIDERMOLYSIS BULLOSA ACQUISITA; EPITOPE MAPPING; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; IMMUNOBLOTTING; IMMUNOELECTRON MICROSCOPY; IMMUNOGOLD LABELING; IMMUNOLOGY; MALE; MOUTH LESION; PATHOLOGY; PHENOTYPE; PLASMAPHERESIS; PROTEIN BINDING; PROTEIN TERTIARY STRUCTURE; SERUM; SKIN BIOPSY; ULTRASTRUCTURE; WESTERN BLOTTING;

ADULT; AGED; AUTOANTIBODIES; BLOTTING, WESTERN; COLLAGEN TYPE VII; EPIDERMIS; EPIDERMOLYSIS BULLOSA ACQUISITA; EPITOPE MAPPING; FEMALE; HUMANS; MALE; MICROSCOPY, IMMUNOELECTRON; MIDDLE AGED; PROTEIN STRUCTURE, TERTIARY;

EID: 0043175119     PISSN: 09066705     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0625.2003.120305.x     Document Type: Article

References (34)

1. Briggaman R A, Wheeler C E J. The epidermal-dermal junction. J Invest Dermatol 1975: 65: 71-84.
2. Carter W G, Wayner E A, Bouchard T S, Kaur P. The role of integrins alpha 2 beta 1 and alpha 3 beta 1 in cell-cell and cell-substrate adhesion of human epidermal cells. J Cell Biol 1990: 110: 1387-1404.
3. Smith L T, Sakai L Y, Burgeson R E, Holbrook K A. Ontogeny of structural components at the dermal epidermal junction in human embryonic and fetal skin: The appearance of anchoring fibrils and type VII collagen. J Invest Dermatol 1988: 90: 480-485.
4. Tidman M J, Eady R A. Evaluation of anchoring fibrils and other components of the dermal-epidermal junction in dystrophic epidermolysis bullosa by a quantitative ultrastructural technique. J Invest Dermatol 1985: 84: 374-377.
5. Sakai L Y, Keene D R, Morris N P, Burgeson R E. Type VII collagen is a major structural component of anchoring fibrils. J Cell Biol 1986: 103: 1577-1580.
6. Christiano A M, Greenspan D S, Lee S, Uitto J. Cloning of human type VII collagen. Complete primary sequence of the alpha: 1 (VII): Chain and identification of intragenic polymorphisms. J Biol Chem 1994: 269: 20256-20262.
7. Li K, Christiano A M, Copeland N G, et al. cDNA cloning and chromosomal mapping of the mouse type VII collagen gene (COL17A1): Evidence for rapid evolutionary divergence of the gene. Genomics 1993: 16: 733-739.
8. Parente M G, Chung L C, Ryynanen J, et al. Human type VII collagen: cDNA cloning and chromosomal mapping of the gene. Proc Natl Acad Sci U S A 1991: 88: 6931-6935.
9. Shimizu H, McDonald J N, Gunner D B, et al. Epidermolysis bullosa acquisita antigen and the carboxy terminus of type VII collagen have a common immunolocalization to anchoring fibrils and lamina densa of basement membrane. Br J Dermatol 1990: 122: 577-585.
10. Zillikens D. Acquired skin disease of hemidesmosomes. J Dermatol Sci 1999: 20: 134-154.
11. Bloching M, Dippel E, Jovanovic S, Hess M, Zouboulis C C. Manifestation of epidermolysis bullosa acquisita (EBA) in the ENT area. HNO 1999: 47: 497-501.
12. Hashimoto T, Ishiko A, Shimizu H, et al. A case of linear IgA bullous dermatosis with IgA anti-type VII collagen autoantibodies. Br J Dermatol 1996: 134: 336-339.
13. Tanaka H, Ishida-Yamamoto A, Hashimoto T, et al. A novel variant of acquired epidermolysis bullosa with auto-antibodies against the central triple-helical domain of type VII collagen. Lab Invest 1997: 77: 623-632.
14. Tanaka T, Furukawa F, Imamura S. Epitope mapping for epidermolysis bullosa acquisita autoantibody by molecularly cloned cDNA for type VII collagen. J Invest Dermatol 1994: 102: 706-709.
15. Tanaka T, Matsuyoshi N, Furukawa F, Imamura S. Production of monoclonal antibodies against the N-terminal noncollagenous domain of type VII collagen encoded by epidermolysis bullosa acquisita antigen cDNA. Dermatol 1994: 1: 42-45.
16. Tanaka T, Takahashi K, Furukawa F, Imamura S. Molecular cloning and characterization of type VII collagen cDNA. Biochem Biophys Res Commun 1992: 183: 958-963.
17. Chen M, Keene D R, Costa F K, Tahk S H, Woodley D T. The carboxyl terminus of type VII collagen mediates antiparallel-dimer formation and constitutes a new antigenic epitope for EBA autoantibodies. J Biol Chem 2001: 27: 27.
18. Burgeson RR. Type VII collagen, anchoring fibrills, and epidermolysis bullosa. J Invest Dermatol 1993: 101: 252-255.
19. Shimizu H, Ishiko A, Masunaga T, et al. Most anchoring fibrils in human skin originate and terminate in the lamina densa. Lab Invest 1997: 76: 753-763.
20. Dmochowski M, Hashimoto T, Bhogal B S, et al. Concomitant occurrence of circulating IgA anti-intercellular and anti-basement membrane zone antibodies in autoimmune blistering diseases: Immunofluorescence and immunoblot studies. J Dermatol 1993: 20:131-137.
21. Dmochowski M, Hashimoto T, Bhogal B S, Black M M, Zone J J, Nishikawa T. Immunoblotting studies of linear IgA disease. J Dermatol Sci 1993: 6: 194-200.
22. Lunstrum G P, Kuo H J, Rosenbaum L M, et al. Anchoring fibrils contain the carboxyl-terminal globular domain of type VII procollagen, but lack the amino-terminal globular domain. J Biol Chem 1987: 262: 13706-13712.
23. Laemmli U K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 1970: 227: 680-685.
24. Gammon W R, Abernethy M L, Padilla K M, et al. Non-collagenous (NC1) domain of collagen VII resembles multidomain adhesion proteins involved in tissue-specific organization of extracellular matrix. J Invest Dermatol 1992: 99: 691-696.
25. Gammon W R, Kowalewski C, Chorzelski T P, Kumar V, Briggaman R A, Beutner Eh. Direct immunofluorescence studies of sodium chloride-separated skin in the differential diagnosis of bullous pemphigoid and epidermolysis bullosa acquisita. J Am Acad Dermatol 1990: 22: 664-670.
26. Shimizu H, McDonald J N, Kennedy A R, Eady R A J. Demonstration of intra- and extra-cellular localization of bullous pemphigoid antigen using cryofixation and freeze substitution for postembedding immuno-electron microscopy. Arch Dermatol Res 1989: 281: 443-448.
27. Tanaka T, Takahashi K, Furukawa F, Imamura S. The epitope for anti-type VII collagen monoclonal antibody (LH7. 2) locates at the central region of the N-terminal non-collagenous domain of type VII collagen. Br J Dermatol 1994: 131: 472-476.
28. Bruckner-Tuderman L, Nilssen O, Zimmermann N T, Kalinke D U, Gedde Dahl T J, Winberg J O. Immunhistochemical and mutational analyses demonstrate that procollagen VII is processed to collagen VII through the removal of the NC-2 domain. J Cell Biol 1995: 131: 551-559.
29. Bedane C, Balding S, Bernard P, et al. Ultrastructural mapping of the 180 kD bullous pemphigoid antigen. [Abstract]. Eur J Dermatol 1995: 5: 433.
30. Griffiths G, ed. Fine Structure Immunocytochemistry. Heidelberg: Springer Verlag, 1993.
31. Altman D G, ed. Practical Statistics for Medical Research. London: Chapman & Hall, 1991.
32. Tidman M J, Eady R A J. Ultrastructural morphometry of the normal human dermal epidermal junction. The influence of age sex and body region on laminar and non-laminar components. J Invest Dermatol 1984: 83: 448-453.
33. Christiano A M, Rosenbaum L M, Chung Honet L C, et al. The large non-collagenous domain (NC-1) of type VII collagen is amino-terminal and chimeric. Homology to cartilage matrix protein, the type III domains of fibronectin and the A domains of von Willebrand factor. Hum Mol Genet 1992: 1: 475-481.
34. Bachinger H P, Morris N P, Lunstrum G P, et al. The relationship of the biophysical and biochemical characteristics of type VII collagen to the function of anchoring fibrils. J Biol Chem 1990: 265: 10095-10101.