UQCRH gene encoding mitochondrial Hinge protein is interrupted by a translocation in a soft-tissue sarcoma and epigenetically inactivated in some cancer cell lines

Oncogene

Volumn 22, Issue 29, 2003, Pages 4586-4593

  Modena, Piergiorgio ^a   Testi, Maria Adele ^a   Facchinetti, Federica ^a   Mezzanzanica, Delia ^a   Radice, Maria Teresa ^a   Pilotti, Silvana ^a   Sozzi, Gabriella ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

EWS; Hinge protein; Mitochondrial complex III; Ovarian carcinoma; Sarcoma

Indexed keywords

AZACITIDINE; MITOCHONDRIAL HINGE PROTEIN; MITOCHONDRIAL PROTEIN; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG;

ARTICLE; BREAST CARCINOMA; CANCER CELL CULTURE; CARCINOGENESIS; CELL STRAIN; CELL STRAIN OAW42; CHROMOSOME 1P; CHROMOSOME 22Q; CHROMOSOME ANALYSIS; CHROMOSOME BREAKAGE; CONTROLLED STUDY; CPG ISLAND; DNA SPLICING; EWS GENE; EXON; FEMALE; GENE; GENE EXPRESSION; GENE INACTIVATION; GENE REARRANGEMENT; GENE STRUCTURE; GENE TRANSLOCATION; GENETIC ANALYSIS; GENETIC CODE; GENOME; HUMAN; HUMAN CELL; METHYLATION; MITOCHONDRION; MOLECULAR CLONING; NUCLEOTIDE SEQUENCE; OVARY CARCINOMA; PRIORITY JOURNAL; PSEUDOGENE; SARCOMA; UQCRH GENE; ZINC FINGER MOTIF; ZSG GENE;

ANTINEOPLASTIC AGENTS; AZACITIDINE; BASE SEQUENCE; BREAST NEOPLASMS; CHROMOSOMES, HUMAN, PAIR 1; CHROMOSOMES, HUMAN, PAIR 22; CPG ISLANDS; DNA METHYLATION; DNA-BINDING PROTEINS; ELECTRON TRANSPORT COMPLEX III; EXONS; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; HUMANS; MOLECULAR SEQUENCE DATA; NEOPLASM PROTEINS; OVARIAN NEOPLASMS; PROMOTER REGIONS (GENETICS); PROTEINS; REPRESSOR PROTEINS; RNA-BINDING PROTEIN EWS; SARCOMA; SOFT TISSUE NEOPLASMS; TRANSLOCATION, GENETIC; TUMOR CELLS, CULTURED;

EID: 0043170826     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1206472     Document Type: Article

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