Glutamate - A transmitter in the tensionfield between toxin and trophine;Glutamat - Ein transmitter im spannungsfeld zwischen toxin und trophin

Fortschritte der Neurologie Psychiatrie

Volumn 71, Issue SUPPL. 1, 2003, Pages

  Römer, Konstanze D ^a   Bleich, S ^a   Kornhuber, J ^a  

^a UNIVERSITY HOSPITAL ERLANGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE RECEPTOR; GLUTAMIC ACID; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; TOXIN;

ARTICLE; CENTRAL NERVOUS SYSTEM; COMPLEX FORMATION; HIPPOCAMPUS; HUMAN; LONG TERM POTENTIATION; NERVE CELL NECROSIS; NERVE CELL PLASTICITY; NEUROLOGIC DISEASE; NEUROTRANSMISSION; NEUROTRANSMITTER RELEASE; NOCICEPTIVE STIMULATION; NONHUMAN; RECEPTOR UPREGULATION; SENSITIZATION;

ANIMALS; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY AMINO ACIDS; GLUTAMIC ACID; HUMANS; NERVE GROWTH FACTORS; NEUROTOXINS; NEUROTRANSMITTER AGENTS; PAIN; RECEPTORS, GLUTAMATE; SYNAPTIC TRANSMISSION;

EID: 0043158755     PISSN: 07204299     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (64)

1. Michaelis EK. Molecular biology of glutamate receptors in the central nervous system and their role in excitotoxicity, oxidative stress and aging. Progress in Neurobiology 1998; 45: 369-415
2. Bleich S, Degner D, Bandelow B, Ahsen N von, Rüther E, Kornhuber J. Plasma Homocysteine is a predictor of alcohol withdrawal seizures. NeuroReport 2000; 11: 2749-2752
3. Bleich S, Spilker K, Kurth C, Degner D, Quintela-Schneider M, Javaheripour K, Rüther E, Kornhuber J, Wiltfang J. Oxidative stress and an altered methionine metabolism in alcoholism. Neurosci Lett 2000; 293: 171-174
4. Bleich S, Degner D, Kornhuber J. Repeated ethanol withdrawal delays development of focal seizures in hippocampal kindling. Alcohol Clin Exp Res 2000; 24: 244-245
5. Bleich S, Degner D, Wiltfang J, Maler JM, Niedmann P, Cohrs S, Mangholz A, Protzig J, Spring R, Rüther E, Kornhuber J. Elevated homocysteine levels in alcohol withdrawal. Alcohol Alcohol 2000; 35: 351-354
6. Heresco-Levy U, Javitt DC. The role of N-methyl-D-aspartate (NMDA) receptor-mediated neurotransmission in the pathophysiology and therapeutics of psychiatric syndroms. European Neuropsychopharmacology 1998; 8: 141-152
7. Parsons CG, Danysz W, Quack G. Glutamate in CNS disorders as a target for drug development: an update. Drug News Perspect 1998; 11: 523-569
8. Spanagel R, Kornhuber J. Glutamatrezeptorantagonisten und Alkoholabhängigkeit. Nervenarzt 1999; 70: 479-481
9. Ozawa S, Kamiya H, Tsuzuki K. Glutamate receptors in the mammalian central nervous system. Progress in Neurobiology 1998; 54: 581-618
10. Danbolt NC. Glutamate uptake. Progress in Neurobiology 2001; 65: 1-105
11. Fadda F, Rossetti ZL. Chronic ethanol consumption: from neuroadaptation to neurodegeneration. Progress in Neurobiology 1998; 56: 385-431
12. Meldrum BS. Glutamate as a neurotransmitter in the brain: Review of physiology and pathology. J Nutr Suppl 2000; 130: 1007-1015
13. Fonnum F. Glutamate: A neurotransmitter in mammalian brain. J Neurochemistry 1984; 42: 1-11
14. Kornhuber J, Bleich S. Memantin. In: Riederer P, Laux G, Pöldinger W (Hrsg). Neuro-Psychopharmaka. Wien: Springer, 1999: 687-704
15. Cotman CW, Kahle JS, Miller SE, Ulas J, Bridges RJ. Excitatory Amino Acid Neurotransmission. In: Bloom FE, Kupfer DJ (Hrsg). Psychopharmacology: The fourth Generation of Progress New York: Raven Press, 1995: 75-85
16. Mayer ML, Westbrook GL. The physiology of excitatory amino acids in the vertebrate nervous system. Prog Neurobiol 1987; 28: 198-276
17. Collingridge GL, Bliss TV. NMDA receptors - their role in long-term potentiation. TINS 1987; 10: 288-293
18. Collingridge GL, Kehl SJ, McLennan H. The antagonism of amino acid-induced excitations of rat hippocampal CA1 neurons in vitro. J Physiol 1983; 334: 19-31
19. Errington ML, Lynch MA, Bliss TV. Long-term potentation in the dentate gyrus: induction and increased glutamate release are blocked by D-aminophosphonovalerate. Neuroscience 1987; 20: 279-284
20. 2+-dependent release of [3H] glutamate from rat dentate gyrus three days after induction of long-term potentation. Neurosci Lett 1987; 83: 107-112
21. Woolf CJ, Salter MW. Neuronal plasticity and the generation of inflammatory pain. Proc Natl Acad Sci 2000; 288: 1765-1769
22. Sandkühler J. Learning and memory in pain pathways. Pain 2000; 88: 113-118
23. Basbaum AI, Fields HL. Endogenous pain control systems: brainstem spinal pathways and endorphin circuitry. Neuroscience 1984; 7: 309-338
24. Castro-Lopes JM, Tavares I, Coimbra A. GABA decreases in the spinal cord dorsal horn after peripheral neurectomy. Brain Res 1993; 620: 287-291
25. Liu H, Wang H, Sheng M, Jan LY, Basbaum AI. Evidence for presynaptic N-methyl-D-aspartate receptors in the spinal cord dorsal horn. Proc Natl Acad Sci USA 1994; 91: 8383-8387
26. Neugebauer V, Kornhuber J, Lücke T, Schaible HG. The clinically available NMDA receptor antagonist memantine is antinociceptive on rat spinal neurones. NeuroReport 1993; 4: 1259-1262
27. Lucas DR, Newhouse JP. The toxic effect of sodium L-glutamate on the inner layers of the retina. AMA Arch Ophthalmol 1957; 58: 193-201
28. Perl TM, Bédard L, Kosatsky T, Hockin JC, Todd ECD, Remis RS. An outbreak of toxic encephalopathy caused by eating mussels contaminated with domoic acid. N Engl J Med 1990; 322: 1775-1780
29. Olney JW, Price MT, Salles KS, Labruyere J, Ryerson R, Mahan K, Friedrich G, Samson L. L-homocysteic acid: an endogenous excitotoxic ligand af the NMDA receptor. Brain Res Bull 1987; 19: 597-602
30. Bouvier M, Szatkowski M, Amato A, Attwell D. The glial cell glutamate uptake carrier countertransports pH-changing anions. Nature 1992; 360: 471-474
31. Clements JD, Lester RAJ, Tong G, Jahr CE, Westbrook GL. The time course of glutamate in the synaptic cleft. Science 1992; 258: 1498-1501
32. Arendash GW, Millard WJ, Dunn AJ, Meyer EW. Long-term neuropathological and neurochemical effects of nucleus basalis lesions in the rat. Science 1987; 238: 952-956
33. Beal MF. Mechanisms of excitotoxicity in neurologic diseases. FASEB J 1992; 6: 3338-3344
34. Chapman AG. Glutamate and epilepsy. J Nutr Suppl 2000; 130: 1043-1045
35. DeBoni U, McLachlan DRC. Controlled induction of paired helical filaments of the Alzheimer type in cultured human neurons, by glutamate and aspartate. J Neurol Sci 1985; 68: 105-118
36. Koh JY, Yang LL, Cotman CW. β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage. Brain Res 1990; 533: 315-320
37. Mattson MP, Cheng B, Davis D, Bryant K, Lieberburg I, Rydel RE. β-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity. J Neurosci 1992; 12: 376-389
38. Meldrum B, Garthwaite J. Excitatory amino acid neurotoxicity and neurodegenerative disease. TiPS 1990; 11: 379-387
39. Lipton SA, Rosenberg PA. Mechanisms of disease: Excitatory amino acids as a final common pathway for neurologic disorders. N Eng J Med 1994; 330: 613-622
40. 3H]MK-801 at therapeutic concentrations in postmortem human frontal cortex. European Journal of Pharmacology 1989; 166: 589-590
41. Kornhuber J, Bormann J, Hübers M, Rusche K, Riederer P. Effects of the 1-amino-adamantanes at the MK-801-binding site of the NMDA-receptor-gated ion channel: a human postmortem brain study. European Journal of Pharmacology 1991; 206: 297-300
42. 2+ block via activation af voltage independent potassium channels. J Neural Transm 1999; 106: 857-867
43. Ripley TL, Little HJ. Effects of chronic ethanol withdrawal hyperexcitability of chronic treatment with a competitive N-methyl-D-aspartate receptor antagonist. J Pharmacol Exp Ther 1995; 272: 112-118
44. Allen HL, Iversen LL. Phencyclidine, dizocilpine, and cerebrocortical neurons. Science 1990; 247: 221
45. Olney JW, Labruyere J, Price MT. Pathological changes induced in cerebrocortical neurons by phencyclidine and related drugs. Science 1989; 244: 1360-1362
46. Minabe Y, Tamura A. Memantine induces heat shock protein HSP70 in the posterior cingulate cortex, retrosplenial cortex and dentate gyrus of rat brain. Brain Res 1996; 740: 1-5
47. Sharp FR, Jasper P, Hall J, Noble L, Sagar SM. MK-801 and ketamine induce heat shock protein HSP72 in injured neurons in posterior cingulate and retrosplenial cortex. Ann Neurol 1991; 30: 801-809
48. Tomitaka S, Hashimoto K, Narita N, Sakamoto A, Rakic P, Sidman RL. Organization of the cerebellar cortex secondary to deficit of granule cells in weaver mutant mice. J Comp Neurol 1973; 152: 133-162
49. Danysz W, Parsons CG, Kornhuber J, Schmidt WJ, Quack G. Amino-adamantanes as NMDA receptor antagonists and antiparkinsonian agents - preclinical studies. Neurosci Biobehav Rev 1997; 21: 455-468
50. Kornhuber J, Weller M, Schoppmeyer K, Riederer P. Amantadine and memantine are NMDA receptor antagonists with neuroprotective properties. J Neural Transm Suppl 1994; 43: 91-104
51. Kornhuber J, Jellinger K, Wiltfang J, Leblhuber F, Riederer P. The N-methyl-D-aspartate receptor channel blocker amantadine does not cause histopathological alterations in human brain tissue. Acta Neuropathol (Berl) 1999; 98: 85-90
52. Kornhuber J, Weller M. Psychotogenicity and NMDA receptor antagonism: implications for neuroprotective pharmacotherapy. Biol Psychiatry 1997; 41: 135-144
53. Misztal M, Frankiewicz T, Parsons CG, Danysz W. Learning deficits induced by chronic intraventriculas infusion of quinolinic acid - protection by MK-801 an memantine. Eur J Pharmacol 1996; 296: 1-8
54. Wenk GL, Danysz W, Roice DD. The effects of mitochondrial failure upon cholinergic toxicity in the nucleus basalis magnocellularis. Eur J Pharmacol 1995; 293: 267-270
55. Kornhuber J, Quack G. Cerebrospinal fluid and serum concentrations of the N-methyl-D-aspartate (NMDA) receptor antagonist memantine in man. Neuroscience letters 1995; 195: 137-139
56. Kroemer RT, Koutsilieri E, Hecht P, Liedl KR, Riederer P, Kornhuber J. Quantitative Analysis of the structural requirements for blockade of the N-methyl-D-aspartate receptor at the phencyclidine binding site. J Med Chem 1998; 41: 393-400
57. Balázs R, Hack N, Jorgensen OS. Stimulation of the N-methyl-D-aspartate receptor has a trophic effect on differentiating cerebellar granule cells. Neuroscience Letters 1988; 87: 80-86
58. Balázs R, Jorgensen OS, Hack N. N-methyl-D-aspartate promotes the survival of cerebellar granule cells in culture. Neuroscience 1988; 27: 437-451
59. Balázs R, Hack N, Jorgensen OS, Cotman CW. N-Methyl-D-aspartate promotes the survival of cerebellar granule cells: pharmacological characterization. Neuroscience Letters 1989; 110: 241-246
60. Balázs R, Resink A, Hack N, Valk JBF van der, Kumar KN, Michaelis E. Neuroscience Letters 1992; 137: 109-113
61. Gallo V, Kingbury A, Balázs R, Jorgensen OS. The role of depolarization in the survival and differentation of cerebellar granule cells in culture. J Neurosci 1987; 7: 2203-2213
62. Rakic P, Sidman RL. Organization of the cerebellar cortex secondary to deficit of ganule cells in weaver mutant mice. J Comp Neurol 1973: 133-163
63. Burgoyne RD, Cambray-Deakin MA. The cellular neurobiology of neuronal development: the cerebellar granule cell. Brain Res Rev 1988; 13: 77-101
64. Rauschecker JP, Hahn S. Ketamine-xylazine anaesthesia blocks consolidation of ocular dominance changes in kitten visual cortex. Nature (London) 1987; 326: 183-185