Familial bipolar disorder and multiple sclerosis: A three-generation HLA family study

Progress in Neuro-Psychopharmacology and Biological Psychiatry

Volumn 27, Issue 5, 2003, Pages 835-839

  Bozikas, Vasilis P ^a,d   Anagnostouli, Maria C ^b   Petrikis, Petros ^a   Sitzoglou, Constantinos ^c   Phokas, Constantinos ^a   Tsakanikas, Constantinos ^b   Karavatos, Athanasios ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

^c Psychiatric Hospital of Thessaloniki   (Greece)

^d NONE   (Greece)

Author keywords

Bipolar disorder; Chromosome 6; HLA; Multiple sclerosis

Indexed keywords

HLA A2 ANTIGEN; HLA ANTIGEN CLASS 1; HLA ANTIGEN CLASS 2; HLA B ANTIGEN; HLA DQ ANTIGEN; HLA DR2 ANTIGEN;

ADULT; ARTICLE; BIPOLAR DISORDER; CASE REPORT; CHROMOSOME 6; CHROMOSOME MAP; COMORBIDITY; DISEASE ASSOCIATION; FAMILIAL DISEASE; FAMILY HISTORY; FAMILY STUDY; FATHER; FEMALE; GENE LOCUS; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; MOTHER; MULTIPLE SCLEROSIS; PHENOTYPE; SEROLOGY;

EID: 0043133765     PISSN: 02785846     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-5846(03)00116-7     Document Type: Article

References (41)

1. Aheam E.P., Steffens D.C., Cassidy F., Van Meter S.A., Provenzale J.M., Seldin M.F., Weisler R.H., Krishna K.R.R. Familial leukoencephalopathy in bipolar disorder. Am. J. Psychiatry. 155:1998;1605-1607.
2. 2 hyperintensities in bipolar disorder: resonance imaging comparison and literature meta-analysis. Am. J. Psychiatry. 152:1995;1139-1144.
3. American Psychiatric Association DSM-IV: Diagnostic and Statistical Manual of Mental Disorders. 4th ed. 1994;American Psychiatric Press, Washington, DC.
4. Brassington J.C., Marsh N.V. Neuropsychological aspects of multiple sclerosis. Neuropsychol. Rev. 8:1998;43-77.
5. Clarke T., Wadhwa U., Leroi I. Psychotic depression: an atypical initial presentation of multiple sclerosis. Psychosomatics. 39:1998;72-75.
6. Cros P., Allibert P., Mandrand B., Tiercy J.M., Mach B. Oligonucleotide genotyping of HLA polymorphism on microtitre plates. Lancet. 340:1992;870-873.
7. Finger S. A happy state of mind: a history of mild elation, denial of disability, optimism, and laughing in multiple sclerosis. Arch. Neurol. 55:1998;241-250.
8. Garfield D.A.S. Multiple sclerosis and affective disorder: 2 case reports of mania with psychosis. Psychother. Psychosom. 44:1985;25-33.
9. Gerhard D.S., Labula M.C., Marshall D., Otten K., Reich T., Todd R.D. A linkage map of chromosome 6 based on 2 large kindreds segregating bipolar affective disorder. DNA Seq. 8:1997;143-146.
10. Giannopoulos Z., Nimatoudis J., Ismailidis G., Fotiadis H., Tourkantonis A. Association of HLA-antigens with manic-depressive psychosis in Greeks. VII South-East Conference for Neurology and Psychiatry, Rome, Italy, 1-3 October. 1987;85. Abstract Book.
11. Hillert J., Olerup O. Multiple sclerosis is associated with genes within or close to HLA-DR-DQ subregion on a normal DR15, DQ6, Dw2 haplotype. Neurology. 43:1993;163-168.
12. Hillert J., Knall T., Vrethem M., Fredrikson S., Ohlson M., Olerup O. The HLA-Dw2 haplotype segregates closely with multiple sclerosis in multiplex families. J. Neuroimmunol. 50:1994;95-100.
13. Horrobin D.F., Lieb J. A biochemical basis for the actions of lithium on behaviour and on immunity: relapsing and remitting disorders of inflammation and immunity such as multiple sclerosis or recurrent herpes as manic-depression of the immune system. Med. Hypotheses. 7:1981;891-905.
14. Hurley R.A., Taber K.H., Zhang J., Hayman L.A. Neuropsychiatric presentation of multiple sclerosis. J. Neuropsychiatry Clin. Neurosci. 11:1999;5-7.
15. Hutchinson M., Stack J., Buckley P. Bipolar affective disorder prior to the onset of multiple sclerosis. Acta Neurol. Scand. 88:1993;388-393.
16. Joffe R.T., Lippert G.P., Gray T.A., Sawa G., Horvath Z. Mood disorder and multiple sclerosis. Arch. Neurol. 44:1987;376-378.
17. Joffe R.T., Lippert G.P., Gray T.A., Sawa G., Horvath Z. Personal and family history of affective illness in patients with multiple sclerosis. J. Affect. Dis. 12:1987;63-65.
18. Korner J., Propping P., Fritze J. HLA-DR2-frequencies in affective disorder. Br. J. Psychiatry. 156:1990;907-908.
19. Kurtzke J.F. Rating neurologic impairment in multiple sclerosis: an expanded disability status scale (EDSS). Neurology. 33:1983;1444-1452.
20. Marsh S.G., Bodmer J.G., Albert E.D., Bodmer W.F., Bontrop R.E., Dupont B., Erlich H.A., Hansen J.A., Mach B., Mayr W.R., Parham P., Petersdorf E.W., Sasazuki T., Schreuder G.M., Strominger J.L., Svejgaard A., Terasaki P.I. Nomeclature for factors of the HLA system, 2000. Hum. Immunol. 62:2001;419-468.
21. Milonas I., Tsounis S., Logothetis I. Epidemiology of multiple sclerosis in northern Greece. Acta Neurol. Scand. 81:1990;43-47.
22. Minden S.L., Schiffer R.B. Affective disorders in multiple sclerosis: review and recommendations for clinical research. Arch. Neurol. 47:1990;98-104.
23. Modrego P.J., Ferrández J. Familial multiple sclerosis with repetitive relapses of manic psychosis in two patients (mother and daughter). Behav. Neurol. 12:2000;175-179.
24. Nurnberger J.I. Jr., Foroud T. Chromosome 6 workshop report. Am. J. Med. Genet. 88:1999;233-238.
25. Olerup O., Zetterquist H. HLA-DR typing by PCR amplification with sequence specific primers (PCR-SSP) in 2 hours: an alternative to serological DR typing in clinical practice including donor-recipient matching in cadaveric transplantation. Tissue Antigens. 39:1992;225-235.
26. Özcan M.E., Taskin R., Banoglu R., Babacan M., Tuncer E. HLA antigens in schizophrenia and mood disorders. Biol. Psychiatry. 39:1996;891-895.
27. Papassavas E.C., Spyropoulou-Vlachou M., Papassavas A.C., Schipper R.F., Doxiadis I.N., Stavropoulos-Giokas C. MHC class I and II phenotype, gene and haplotype frequencies in Greeks using molecular typing data. Hum. Immunol. 61:2000;615-623.
28. Pine D.S., Douglas C.J., Charles E., Davies M., Kahn D. Patients with multiple sclerosis presenting to psychiatric hospitals. J. Clin. Psychiatry. 56:1995;297-306.
29. Poser C.M., Paty D.W., Scheinberg L., McDonald W.I., David E.A., Ebers G.C., Johnson K.P., Sibley W.A., Silberberg D.H., Tourtelotte W.W. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Ann. Neurol. 13:1983;227-231.
30. Pugliatti M., Sotgiu S., Rosati G. The worldwide prevalence of multiple sclerosis. Clin. Neurol. Neurosurg. 104:2002;182-191.
31. Reischies F.M., Baum K., Nehring C., Schörner W. Psychopathological symptoms and magnetic resonance findings in multiple sclerosis. Biol. Psychiatry. 33:1993;676-678.
32. Rodgers J., Bland R. Psychiatric manifestations of multiple sclerosis: a review. Can. J. Psychiatry. 41:1996;441-445.
33. Sadovnick A.D., Remick R.A., Allen J., Swartz E., Yee I.M.L., Eisen K., Farquhar R., Hashimoto S.A., Hooge J., Kastrukoff L.F., Morrison W., Nelson J., Oger J., Paty D.W. Depression and multiple sclerosis. Neurology. 46:1996;628-632.
34. Schiffer N.M., Wineman M., Weitkamp L.R. Association between bipolar affective disorder and multiple sclerosis. Am. J. Psychiatry. 143:1986;94-95.
35. Schiffer R.B., Weitkamp L.R., Wineman M., Guttormsen S. Multiple sclerosis and affective disorder. Family history, sex, and HLA-DR antigens. Arch. Neurol. 45:1988;1345-1348.
36. Shapiro R.W., Ryder L.P., Svejgaard A., Rafaelsen O.J. HLA antigens and manic-depressive disorders: further evidence of an association. Psychol. Med. 7:1977;387-396.
37. Skegg K. Multiple sclerosis presenting as a pure psychiatric disorder. Psychol. Med. 23:1993;909-914.
38. Skegg K., Corwin P.A., Skegg D.C.G. How often is multiple sclerosis mistaken for a psychiatric disorder? Psychol. Med. 18:1988;733-736.
39. Smeraldi E., Negri F., Melica A.M., Scorza-Smeraldi R., Fabio G., Bonara P., Bellodi L., Sacchetti E., Sabbadini-Villa M.G., Cazzullo C.L., Zanussi C. HLA typing and affective disorders: a study in the Italian population. Neuropsychobiology. 4:1978;344-352.
40. Xu C., Dai Y., Lorentzen J.C., Dahlman I., Olsson T., Hillert J. Linkage analysis in multiple sclerosis of chromosomal regions syntenic to experimental autoimmune disease loci. Eur. J. Hum. Genet. 9:2001;458-463.
41. Young C.R., Weiss E.L., Bowers M.B., Mazure C.M. The differential diagnosis of multiple sclerosis in bipolar sclerosis. J. Clin. Psychiatry. 58:1997;123.