Identification of variations in SzP proteins of Streptococcus equi subspecies zooepidemicus and the relationship between protein variants and clinical signs of infection in horses

American Journal of Veterinary Research

Volumn 64, Issue 8, 2003, Pages 976-981

  Walker, Richard L ^a   Runyan, Catherine A ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL SURFACE PROTEIN; GLUTAMIC ACID; LYSINE; PROLINE; SIGNAL PEPTIDE; SZP PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; BACTERIUM ISOLATE; CLINICAL FEATURE; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC HETEROGENEITY; HORSE DISEASE; MALE; NONHUMAN; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PEPTIDE ANALYSIS; POLYMERASE CHAIN REACTION; PROTEIN ANALYSIS; PROTEIN MOTIF; PROTEIN VARIANT; STREPTOCOCCUS EQUI; STREPTOCOCCUS EQUI ZOOEPIDEMICUS; STREPTOCOCCUS INFECTION;

ABORTION, VETERINARY; ABSCESS; AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CELLULITIS; ENDOMETRITIS; FEMALE; HORSE DISEASES; HORSES; LYMPH NODES; MALE; MOLECULAR SEQUENCE DATA; PHYLOGENY; PNEUMONIA; STREPTOCOCCAL INFECTIONS; STREPTOCOCCUS EQUI; SURGICAL WOUND INFECTION; VARIATION (GENETICS);

ANIMALIA; BACTERIA (MICROORGANISMS); EQUIDAE; EQUUS CABALLUS; STREPTOCOCCUS; STREPTOCOCCUS EQUI; STREPTOCOCCUS EQUI SUBSP. ZOOEPIDEMICUS;

EID: 0043123210     PISSN: 00029645     EISSN: None     Source Type: Journal    
DOI: 10.2460/ajvr.2003.64.976     Document Type: Article

References (19)

1. Sweeney CR. Bacterial infection of the equine lung, in Proceedings. Am Coll Vet Intern Med 1988;6:31-32.
2. Carr EA, Carlson GP, Wilson WD, et al. Acute hemorrhagic pulmonary infarction and necrotizing pneumonia in horses: 21 cases (1967-1993). J Am Vet Med Assoc 1997;210:1774-1778.
3. Skjold SA, Quie PG, Fries LA, et al. DNA fingerprinting of Streptococcus zooepidemicus (Lancefield group C) as an aid to epidemiological study. J Infect Dis 1987;155:1145-1150.
4. Anzai T, Timoney JE, Kuwamoto Y, et al. Polymerase chain reaction-restriction fragment length polymorphism analysis of the SzP gene of Streptococcus zooepidemicus isolated from the respiratory tract of horses. Am J Vet Res 2002;63:1298-1301.
5. Timoney JF, Artiushin SC, Boschwitz JS. Comparison of the sequences and functions of Streptococcus equi M-like proteins SeM and SzPSe. Infect Immun 1997;65:3600-3605.
6. Timoney JF, Walker J, Zhou M, et al. Cloning and sequence analysis of a protective M-like protein gene from Streptococcus equi subsp. zooepidemicus. Infect Immun 1995;63:1440-1445.
7. Anzai T, Walker JA, Blair MB, et al. Comparison of the phenotypes of Streptococcus zooepidemicus isolated from tonsils of healthy horses and specimens obtained from foals and donkeys with pneumonia. Am J Vet Res 2000;61:162-166.
8. Alam S, Brailsford SR, Whiley RA, et al. PCR-Based methods for genotyping viridans group streptococci. J Clin Microbiol 1999; 37:2772-2776.
9. Walker JA, Timoney JF. Molecular basis of variation in protective SzP proteins of Streptococcus zooepidemicus. Am J Vet Res 1998; 59:1129-1133.
10. Swiss Institute of Bioinformatics. ExPASy molecular biology server. DNA -> Protein translate tool. Available at: http://us.expasy.org/. Accessed Oct 9, 2002.
11. Thompson JD, Higgins DG, Gibson TJ. CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res 1994;22:4673-4680.
12. Institut Pasteur. Biological software. Clustalw: multiple alignments. Available at: http://bioweb.pasteur.fr/seqanal/interfaces/clustalw-simple.html. Accessed Oct 16, 2002.
13. Nielsen H, Engelbrecht J, Brunak S, et al. Identification of prokaryotic and eukaryotic signal peptides and prediction of their cleavage sites. Protein Eng 1997;10:1-6.
14. Center for Biological Sequence Analysis. World wide web prediction server. SignalP V1.1. Available at: http://www.cbs.dtu.dk/services/SignalP/. Accessed Nov 20, 2002.
15. Tamura K. TreeExplorer, version 2.12. Available at: http://evolgen.biol.metro-u.ac.jp/TE/TE_man.html. Accessed Oct 28, 2002.
16. Al-Ghamdi GM, Kapur V, Ames TR, et al. Use of repetitive sequence-based polymerase chain reaction for molecular epidemiologic analysis of Streptococcus equi subspecies equi. Am J Vet Res 2000; 61:699-705.
17. Navarre WW, Schneewind O. Surface proteins of gram-positive bacteria and mechanisms of their targeting to the cell wall envelope. Microbiol Mol Biol Rev 1999;63:174-229.
18. Nicholson ML, Ferdinand L, Sampson JS, et al. Analysis of immunoreactivity to a Streptococcus equi subsp. zooepidemicus M-like protein to confirm an outbreak of poststreptococcal glomerulonephritis, and sequences of M-like proteins from isolates obtained from different host species. J Clin Microbiol 2000; 38:4126-4130.
19. Patti JM, Allen BL, McGavin MJ, et al. MSCRAMM-mediated adherence of microorganisms to host tissues. Annu Rev Microbiol 1994; 48:585-617.