Current concepts in the treatment of acne: Report from a clinical roundtable

Cutis

Volumn 72, Issue 1 SUPPL., 2003, Pages 4-15

  Berson, Diane S ^b   Chalker, Daniel K ^c   Harper, Julie C ^d   Leyden, James J ^e   Shalita, Alan R ^a   Webster, Guy F ^f  

^a SUNY DOWNSTATE MEDICAL CENTER   (United States)

^b WEILL CORNELL MEDICAL COLLEGE   (United States)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e UNIVERSITY OF PENNSYLVANIA   (United States)

^f THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPALENE; ANTI ACNE AGENT; ANTIBIOTIC AGENT; BENZOYL PEROXIDE; CLINDAMYCIN; DOXYCYCLINE; ERYTHROMYCIN; ISOTRETINOIN; MACROLIDE; MINOCYCLINE; ORAL CONTRACEPTIVE AGENT; RETINOIC ACID; RETINOID; SALICYLIC ACID; SPIRONOLACTONE; TAZAROTENE; TETRACYCLINE; TOPICAL ANTIINFECTIVE AGENT;

ACNE VULGARIS; ADRENAL HYPERPLASIA; ANDROGEN SYNTHESIS; ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL SKIN DISEASE; BREAKTHROUGH BLEEDING; CLINICAL TRIAL; COMEDO; CONTACT DERMATITIS; CORYNEBACTERIUM ACNES; DESQUAMATION; DRUG PULSE THERAPY; DRUG TOLERABILITY; DRY SKIN; ERYTHEMA; GASTROINTESTINAL DISEASE; GASTROINTESTINAL SYMPTOM; HORMONAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPERPIGMENTATION; HYPERSENSITIVITY; MENSTRUAL IRREGULARITY; MENTAL INSTABILITY; MONOTHERAPY; NONHUMAN; PATHOGENESIS; PATIENT COMPLIANCE; PHOTOSENSITIVITY; PRURITUS; PSEUDOMEMBRANOUS COLITIS; PUBERTY; SEBACEOUS GLAND; SEBUM SECRETION; SIDE EFFECT; SKIN ALLERGY; SKIN CARE; SYSTEMIC THERAPY; TERATOGENICITY; TOPICAL TREATMENT; VAGINA CANDIDIASIS; XEROSIS;

EID: 0043073376     PISSN: 00114162     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (49)

1. Anderson AS, Galdys GJ, Green RC, et al. Improved reduction of cutaneous bacteria and free fatty acids with new benzoyl peroxide gel. Cutis. 1975;16:307-310.
2. Bershad S. Developments in topical retinoid therapy for acne. Semin Cutan Med Surg. 2001;20:154-161.
3. Bershad S, Kranjac Singer G, Parente JE, et al. Successful treatment of acne vulgaris using a new method: results of a randomized vehicle-controlled trial of short-contact therapy with 0.1% tazarotene gel. Arch Dermatol. 2002;138:481-489.
4. Berson DS, Shalita AR. The treatment of acne: the role of combination therapies. J Am Acad Dermatol. 1995;32:S31-S41.
5. Burke B, Eady EA, Cunliffe WJ. Benzoyl peroxide versus topical erythromycin in the treatment of acne vulgaris. Br J Dermatol. 1983;108:199-204.
6. Burton J and the Dermatology Research Group. A placebo-controlled study to evaluate the efficacy of topical tetracycline and oral tetracycline in the treatment of mild to moderate acne. J Int Med Res. 1990;18:94-103.
7. Chalker DK, Shalita A, Smith JG, et al. A double-blind study of the effectiveness of a 3% erythromycin and 5% benzoyl peroxide combination in the treatment of acne vulgaris. J Am Acad Dermatol. 1983;9:933-936.
8. Eady EA, Cove JH, Holland KT, et al. Erythromycin-resistant propionibacteria in antibiotic-treated acne patients: association with therapeutic failure. Br J Dermatol. 1989;121:51-57.
9. Eady EA, Farmery MR, Ross JI, et al. Effects of benzoyl peroxide and erythromycin alone and in combination against antibiotic-sensitive and -resistant skin bacteria from acne patients. Br J Dermatol. 1994;131:331-336.
10. Eady EA, Joanes DN, Cunliffe WJ. Topical antibiotics for the treatment of acne vulgaris: a critical evaluation of the literature on their clinical benefit and comparative efficacy. J Dermatol Treat. 1990;1:215-226.
11. Esterly NB, Furey NL, Flanagan LE. The effect of antimicrobial agents on leukocyte chemotaxis. J Invest Dermatol. 1978;70:51-55.
12. Gollnick H, Cunliffe W, Berson D, et al. Recommendations for the management of acne. J Am Acad Dermatol. In press.
13. Gollnick H, Schramm M. Topical drug treatment in acne. Dermatology. 1998;196:119-125.
14. Gupta MA, Gupta AK. The psychological comorbidity in acne. Clin Dermatol. 2001;19:360-363.
15. Joiner KA, Lowe BR, Dzink JL, et al. Antibiotic levels in infected and sterile subcutaneous abscesses in mice. J Infect Dis. 1981;143:487-494.
16. Katsambas AD. Why and when the treatment of acne fails. Dermatology. 1998;196:158-161.
17. Kelly AP. Acne and related disorders. In: Sams WM Jr, Lynch PJ, eds. Principles and Practice of Dermatology. New York, NY: Churchill Livingstone; 1990:781-796.
18. Kim J, Ochoa MT, Krutzik SR, et al. Activation of toll-like receptor 2 in acne triggers inflammatory cytokine responses. J Immunol. 2002;169:1535-1541.
19. Klempner MS, Styrt B. Prevention of recurrent staphylococcal skin infections with low-dose oral clindamycin therapy. JAMA. 1998;260:2682-2685.
20. Kligman AM. An overview of acne. J Invest Dermatol. 1974;62:268-287.
21. Kligman AM. Spontaneous involution of acne. In: Kligman AM, Plewig G, eds. Acne and Rosacea. 2nd ed. Berlin: Springer Verlag; 1993:711.
22. Kraning KK, Odland GF. Prevalence, morbidity, and cost of dermatological diseases. J Invest Dermatol. 1979;73(suppl):395-401.
23. Lavker RM, Leyden JJ. Lamellar inclusions in follicular horny cells: a new aspect of abnormal keratinization. J Ultrastruct Res. 1979;69:362-370.
24. Leyden JJ. New understandings of the pathogenesis of acne. J Am Acad Dermatol. 1995;32:S15-S25.
25. Leyden JJ. Therapy for acne vulgaris. N Engl J Med. 1997;336:1156-1162.
26. Lookingbill DP, Chalker DK, Lindholm JS, et al. Treatment of acne with a combination clindamycin/benzoyl peroxide gel compared with clindamycin gel, benzoyl peroxide gel and vehicle gel: combined results of two double-blind investigations. J Am Acad Dermatol. 1997;37:590-595.
27. Lucky AW, Biro FM, Simbartl LA, et al. Predictors of severity of acne vulgaris in young adolescent girls: results of a five-year longitudinal study. J Pediatr. 1997;130:30-39.
28. Lucky AW, Ratterman J. Topical erythromycin/benzoyl peroxide gel enhances the effectiveness of low-dose oral tetracycline in moderate acne vulgaris: results of a double-blind study. Cutis. 1992;49:116-119.
29. Lyons RE. Comparative effectiveness of benzoyl peroxide and tretinoin in acne vulgaris. Int J Dermatol. 1978;17:246-252.
30. Mills OH Jr, Berger RS. Comparison of the combination of erythromycin/benzoyl peroxide topical gel to clindamycin phosphate solution in treatment of acne vulgaris. Cutis. 1992;49(suppl 6A):5-7.
31. Nacht S, Young D, Beasley JN Jr, et al. Benzoyl peroxide: percutaneous penetration and metabolic disposition. J Am Acad Dermatol. 1981;4:31-37.
32. Prokesch RC, Hand WL. Antibiotic entry into human polymorphonuclear leukocytes. Antimicrob Agents Chemother. 1982;21:373-380.
33. Rietschel R, Duncan BS. Clindamycin phosphate used in combination with tretinoin in the treatment of acne. Int J Dermatol. 1983;22:41-43.
34. Ross JI, Shelling AM, Eady EA, et al. Phenotypic and genotypic characterization of antibiotic-resistant Propionibacterium acnes isolated from acne patients attending dermatology clinics in Europe, the U.S.A., Japan and Australia. Br J Dermatol. 2001;144:339-346.
35. Sande MA, Mandell GL. Antibacterial agents. In: Gilman AG et al, eds. The Pharmacological Basis of Therapeutics. 3rd ed. New York, NY: Macmillan Publishing; 1985:1188-1190.
36. Schmidt JB, Neumann R, Knobler R, et al. Sebum suppression by benzoylperoxide. Dermatologica. 1985;170:165-169.
37. Shalita AR, Smith EB, Bauer E. Topical erythromycin vs. clindamycin therapy for acne: a multicenter, double-blind comparison. Arch Dermatol. 1984;120:351-355.
38. Shalita AR. Comparison of a salicylic acid cleanser and a benzoyl peroxide wash in the treatment of acne vulagris. Clin Ther. 1989;11:264-267.
39. Shalita AR, Chalker DK, Ellis CN, et al. A multicenter, double-blind, controlled study of the combination of erythromycin/benzoyl peroxide, erythromycin alone, and benzoyl peroxide alone in the treatment of acne vulgaris. Cutis. 1992;49(suppl 6A):1-4.
40. Stewart ME, Downing DT, Cook JS, et al. Sebaceous gland activity and serum dehydroepiandrosterone sulfate levels in boys and girls. Arch Dermatol. 1992;128:1345-1348.
41. Stoughton RB, Resh W. Topical clindamycin in the control of acne vulgaris. Cutis. 1976;17:551-554.
42. Swinyer LJ, Baker MD, Swinyer TA, et al. A comparative study of benzoyl peroxide and clindamycin phosphate for treating acne vulgaris. Br J Dermatol. 1988;199:615-622.
43. Thiboutot DM, Lookingbill DP. Acne: acute or chronic disease? J Am Acad Dermatol. 1995;32:S222-S225.
44. Thomsen RJ, Stranieri A, Knutson D, et al. Topical clindamycin treatment of acne. clinical, surface lipid composition, and quantitative surface microbiology response. Arch Dermatol. 1980;116:1031-1034.
45. Toyoda M, Morohashi M. An overview of topical antibiotics for acne treatment. Dermatology. 1998;196:130-134.
46. Tucker SB, Tausend R, Cochran R, et al. Comparison of topical clindamycin phosphate, benzoyl peroxide, and a combination of the two for the treatment of acne vulgaris. Br J Dermatol. 1984;110:487-492.
47. Webster GF. Acne vulgaris. BMJ. 2002;325:475-479.
48. Webster GF. Inflammation in acne vulgaris. J Am Acad Dermatol. 1995;33:247-253.
49. Wechsler HL, Kirk J, Stone J. Acne treated with a topical tetracycline preparation: results of a one-year multi-group study. Int J Dermatol. 1978;17:237-242.