Fungal colonization and/or infection in intensive care units. Multicenter study of 1,562 patients;Colonización y/o infección por hongos en unidades de cuidados intensivos. Estudio multicéntrico de 1.562 pacientes

Medicina Clinica

Volumn 121, Issue 5, 2003, Pages 161-166

  Álvarez Lerma, Francisco ^a   Palomar, Mercedes ^b   León, Cristóbal ^c   Olaechea, Pedro ^d   Cerdá, Enrique ^e   Bermejo, Begoña ^f  

^a HOSPITAL DEL MAR   (Spain)

^b HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^c HOSPITAL UNIVERSITARIO DE VALME   (Spain)

^d HOSPITAL DE GALDAKAO   (Spain)

^e HOSPITAL UNIVERSITARIO DE GETAFE   (Spain)

^f Universidad Pública de Navarra   (Spain)

Author keywords

Candida spp; Critically ill patient; Fungal colonization; Fungal infection; Intensive care unit (ICU)

Indexed keywords

AMINOGLYCOSIDE ANTIBIOTIC AGENT; ANTIBIOTIC AGENT; ANTIFUNGAL AGENT; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; CARBAPENEM; CEPHALOSPORIN; CORTICOSTEROID DERIVATIVE; MACROLIDE; PENICILLIN G; POLYPEPTIDE ANTIBIOTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; TETRACYCLINE DERIVATIVE; TUBERCULOSTATIC AGENT; UREIDOPENICILLIN;

ADOLESCENT; ADULT; ANTIBIOTIC THERAPY; ARTICLE; ARTIFICIAL VENTILATION; BACTERIAL COLONIZATION; BLOOD CULTURE; CANDIDA ALBICANS; CHILD; CLINICAL OBSERVATION; CONTROLLED STUDY; CORTICOSTEROID THERAPY; CRITICAL ILLNESS; DISEASE CLASSIFICATION; DISEASE SEVERITY; FUNGUS ISOLATION; HOSPITAL ADMISSION; HUMAN; INFANT; INFECTION RATE; INFECTION RISK; INTENSIVE CARE UNIT; LUNG INFECTION; MAJOR CLINICAL STUDY; MEDICAL ASSESSMENT; MICROBIOLOGICAL EXAMINATION; MULTICENTER STUDY; MYCOSIS; OROPHARYNX; SCORING SYSTEM; SOLID TUMOR; URINARY TRACT INFECTION;

EID: 0043066675     PISSN: 00257753     EISSN: None     Source Type: Journal    
DOI: 10.1157/13049416     Document Type: Article

References (28)

1. Pfaller M, Wenzel R. Impact of the changing epidemiology of fungal infections in the 1990s. Eur J Clin Microbiol Infect Dis 1992;11:287-91.
2. Beck-Sague C, Jarvis WR. Secular trends in the epidemiology of nosocomial fungal infections in the United States 1908-1990, National Nosocomial Infections Surveillance System. J Infect Dis 1993;167:1247-51.
3. Wenzel RP. Nosocomial candidemia: risk factors and attributable mortality. Clin Infect Dis 1995; 20:1531-4.
4. Vincent JL, Bihari DJ, Suter PM, Bruining HA, White J, Nicolas-Chanion MH, et al. The prevalence of nosocomial infection in intensive care unit in Europe. Results of the Europen Prevalence of infection in intensive care (EPIC) study. JAMA 1995;274:639-44.
5. Morera Y, Torres-Rodríguez JM, Catalán I, Granadero A, Josic Z, Álvarez-Lerma F. Candiduria en pacientes con sonda uretral ingresados en una unidad de cuidados intensivos. Etiología y sensibilidad in vitro al fluconazol. Med Clin (Barc) 2002; 118:580-2.
6. Edwards JE (Conference chairman). International Conference for the Development of a Consensus on the management and Prevention of Severe Candidal Infections. Clin Infect Dis 1997; 25:43-59.
7. Conferencia de Consenso de la Sociedad Española de Medicina Intensiva Crítica y Unidades Coronarias (SEMICYUC). Infecciones por Candida spp. en pacientes críticos. Med Intensiva 1999;23:3-7.
8. Knaus WA, Draper EA, Wagner DP, Zimmerman JE. APACHE II: a severity of disease classification system. Crit Care Med 1985;13:818-29.
9. Centers for Disease Control 1993. Revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adult. MMWR 1992;41(RR-17):1-19.
10. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections. Am J Infect Control 1988;16:128-40.
11. Jorda R, Nolla J, León C, León MA, Pontes MJ and EPCAN Group Project. An epidemiological study of fungal infections in ICU. A spanish multicenter study. Intensive Care Med 2000; 26(Suppl 3):234.
12. Grupo de Trabajo EPINE. Evolución de la prevalencia de las Infecciones Nosocomiales en los hospitales españoles. EPINE 1990-1999. Madrid: IM&C, S.A., 2001.
13. Álvarez-Lerma F. Epidemiología de la infección fúngica en pacientes críticos. En: Álvarez-Lerma F, editor, Infecciones fúngicas en pacientes críticos. Madrid: Ergón, 2002; p. 7-22.
14. Richardson MD, Kokki M. Therapeutic guidelines in systemic fungal infections. London Current Medical Literature Ltd., 2001; p. 2-6.
15. Ascioglu S, Rex JH, De Pauw B, Bennet JE, Bille J, Crokaert F, et al. Defining opportunistic invasive fungal infections in immunocompromised patients with cancer and hematopoietic stam cell transplnats: an international consensus. Clin Infect Dis 2002;34:7-14.
16. Pfaller MA, Jones RN, Messer SA, Edmond MB, Wenzel RP. National surveillance of nosocomial blood stream infection due to Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. Diagn Microbiol Infect Dis 1998;31:327-32.
17. Pfaller MA, Jones RN, Messer SA, Edmond MB, Wenzel RP. National surveillance of nosocomial blood stream infection due to species of Candida other than Candida albicans: frequency of occurrence and antifungal susceptibility in the SCOPE Program. Diagn Microbiol Infect Dis 1998; 30:121-9.
18. Nguyen MH, Peacock JE Jr, Morris AJ, Tanner DC, Nguyen ML, Snydman DR, et al. The changing face of candidemia: emergence of non-Candida albicans species and antifungal resistance. Am J Med 1996;100:617-23.
19. Jarvis WR. Epidemiology of nosocomial fungal infections, with emphasis on Candida species. Clin Infect Dis 1995;20:1526-30.
20. Pfaller MA, Diekema DJ, Jones RN, Sader HS, Fluit AC, Hollis RJ, et al. International surveillance of bloodstream infections due to Candida species: frequency of ocurrence and in vitro susceptibilities to fluconazole, ravuconazole and voriconazole of isolates collected from 1997 through 1999 in the SENTRY antimicrobial surveillance program. J Clin Microbiol 2001;39:3254-9.
21. Adell C, Trilla A, Bruguera M, Giol M, Salles M, Bayas JM, et al. Infecciones nosocomiales por hongos oportunistas: análisis de una serie de noticias publicadas en la prensa española. Med Clin (Barc) 2000;114:259-63.
22. Wey SB, Mori M, Pfaller MA, Woolson RF, Wenzel RP. Hospital-acquired candidemia. A matched case-control study. Arch Intern Med 1989; 149:2349-53.
23. Petri MG, Konig J, Moecke HP, Gramm HJ, Barkow H, Kujath P, et al. Epidemiology of invasive mycosis in ICU patients: a prospective multicenter study in 435 non-neutropenic patients. Intens Care Med 1977;23:317-25.
24. Pittet D, Monod M, Suter PM, Frenk E, Auckenthaler R. Candida colonization and subsequent infections in critically ill surgical patients. Ann Surg 1994;220:751-8.
25. Díaz E, Villagrá A, Rello J, Valles J y Grupo de Estudio de Bacteriemias en UCI. Med Intensiva 1999;23 (número extraordinario):25-31.
26. Karabinis A, Hill C, Leclercq B, Tancrede C, Baume D, Andremont A. Risk factors for candidemia in cancer patients: a case-controlled study. J Clin Microbiol 1988;26:429-32.
27. Fraser VJ, Jones M, Dunkel J, Storfer S, Medoff G, Dunagan WC. Candidemia in a tertiary care hospital: epidemiology, risk factors, and predictors of mortality. Clin Infect Dis 1992;15:414-21.
28. Calandra T, Bille J, Schneider R, Mosimann F, Francoli P. Clínica significance of Candlda isolated from peritoneum in surgical patients. Lancet 1989;2:1437-40.