Insoluble versus soluble polymer-assisted synthesis. A first approach forthe preparation of a Biginelli compound

Arkivoc

Volumn 2003, Issue 4, 2003, Pages 93-101

  Vanden Eynde, Jean Jacques ^a,b   Watté, Olivier ^b  

^a XAVIER UNIVERSITY OF LOUISIANA   (United States)

^b UNIVERSITY OF MONS   (Belgium)

Author keywords

Biginelli; Dendrimer; Liquid phase synthesis; Pyrimidine; Solid phase synthesis

Indexed keywords

1,2,3,4 TETRAHYDRO 6 METHYL 2 OXO 4 PHENYLPYRIMIDINE 5 CARBOXYLATE; CARBOXYLIC ACID DERIVATIVE; DENDRIMER; MACROGOL; POLYMER; POLYOL; POLYSTYRENE CO ALLYL ALCOHOL; RESIN; THIOUREA; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL STRUCTURE; COMPARATIVE STUDY; ESTERIFICATION; POLYMERIZATION; SOLID; SYNTHESIS;

EID: 0043030206     PISSN: 14246376     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. e.g. Terret, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron 1995, 51, 8135. Fruchtel, J.S.; Jung. G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Hermkens, P.H.H.; Opttenheijm, H.C.J.; Rees, D. Tetrahedron 1997, 53, 5643.
2. e.g. Terret, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron 1995, 51, 8135. Fruchtel, J.S.; Jung. G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Hermkens, P.H.H.; Opttenheijm, H.C.J.; Rees, D. Tetrahedron 1997, 53, 5643.
3. e.g. Terret, N.K.; Gardner, M.; Gordon, D.W.; Kobylecki, R.J.; Steele, J. Tetrahedron 1995, 51, 8135. Fruchtel, J.S.; Jung. G. Angew. Chem. Int. Ed. Engl. 1996, 35, 17. Hermkens, P.H.H.; Opttenheijm, H.C.J.; Rees, D. Tetrahedron 1997, 53, 5643.
4. e.g. Bonara, G.M. Applied Biochem. Biotech. 1995, 54, 3. Gravert, D.J.; Janda, K.D. Chem. Rev. 1997, 97, 489.
5. e.g. Bonara, G.M. Applied Biochem. Biotech. 1995, 54, 3. Gravert, D.J.; Janda, K.D. Chem. Rev. 1997, 97, 489.
6. Vanden Eynde, J.J.; Rutot, D. Tetrahedron 1999, 55, 2687.
7. Kappe, C.O. Eur. J. Med. Chem. 2000, 35, 1043.
8. Biginelli, P. Gazz. Chim. Ital. 1893, 23, 360.
9. Kappe, C.O. Tetrahedron 1993, 49, 6937.
10. Kappe, C.O. Bioorg. Med. Chem. Lett. 2000, 10, 49.
11. Kantchev, A.B.; Parquette, J.R. Tetrahedron Lett. 1999, 40, 8049.
12. Obrecht, D.; Abrecht, C.; Grieder, A.; Villigordo, J.M. Helv. Chim. Acta 1997, 80, 65.
13. Charlot, G. in Les Méthodes de la Chimie Analytique Ed. Masson (Paris, France), 1966.
14. Milcent, R.; Malanda, J.-C.; Barbier, G.; Vaissermann, J. J. Heterocycl. Chem. 1997, 34, 329.