Heterozygous prothrombin G20210A gene mutation in a patient with livedoid vasculitis

Archives of Dermatology

Volumn 139, Issue 8, 2003, Pages 1081-1083

  Gotlib, Jason ^b   Kohler, Sabine ^b   Reicherter, Paul ^b   Oro, Anthony E ^b   Zehnder, James L ^a  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ALTEPLASE; ANTIBIOTIC AGENT; ANTICOAGULANT AGENT; ANTITHROMBOCYTIC AGENT; BACITRACIN ZINC; BETAMETHASONE; CARBAMAZEPINE; CHLORHEXIDINE; CORTICOSTEROID; DANAZOL; LOW MOLECULAR WEIGHT HEPARIN; MEDROXYPROGESTERONE; NEOMYCIN; PENTOXIFYLLINE; POLYMYXIN B; PROSTACYCLIN; PROTHROMBIN; PSEUDOMONIC ACID; WARFARIN;

ADULT; ARTICLE; CASE REPORT; FEMALE; GENE MUTATION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; HYPERCOAGULABILITY; LEG ULCER; MENORRHAGIA; PRIORITY JOURNAL; SEGMENTED HYALINIZING VASCULITIS; SEIZURE; SKIN BIOPSY; SKIN ULCER; THROMBOEMBOLISM; VASCULAR DISEASE; VASCULITIS;

EID: 0043023631     PISSN: 0003987X     EISSN: None     Source Type: Journal    
DOI: 10.1001/archderm.139.8.1081-b     Document Type: Article

References (7)

1. Tran MD, Bécherel PA, Cordel N, Piette JC, Francès C. Idiopathic livedoid vasculitis. Ann Dermatol Venereol. 2001;128:1003-1007.
2. Poort SR, Rosendaal FR, Reitsma PH, Bertina RM. A common genetic variation in the 3′-untranslated region of the prothrombin gene is associated with elevated plasma prothrombin levels and an increase in venous thrombosis. Blood. 1996;88:3698-3703.
3. Vicente V, González-Conejero R, Rivera, J, Corral J. The prothrombin gene variant 20210A in venous and arterial thromboembolism. Haematologica. 1999;84:356-362.
4. Grobb JJ, Bonerandi JJ. Thrombotic skin disease as a marker of the anticardiolipin syndrome: livedo vasculitis and distal gangrene associated with abnormal serum antiphospholipid activity. J Am Acad Dermatol. 1989;20:1063-1069.
5. Calamia KT, Balabanova M, Perniciaro C, Walsh JS. Livedo (livedoid) vasculitis and the factor V Leiden mutation: additional evidence for abnormal coagulation. J Am Acad Dermatol. 2002;46:133-137.
6. Hegemann B, Helmbold P, Marsch WC. Livedoid vasculitis with ulcerations: the role of antithrombin III deficiency and its therapeutic consequences. Arch Dermatol. 2002;138:841-842.
7. Baccard M, Vignon-Pennamen MD, Janier M, Schrobohaci ML, Dubertret L. Livedo vasculitis with protein C system deficiency. Arch Dermatol. 1992;128:1410-1411.