Brain networks and clinical penetrance: Lessons from hyperkinetic movement disorders

Current Opinion in Neurology

Volumn 16, Issue 4, 2003, Pages 471-474

  Eidelberg, David ^a  

^a Center for Neurosciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; BRAIN FUNCTION; EDITORIAL; GENE EXPRESSION; GENE MUTATION; HUMAN; HUNTINGTON CHOREA; HYPERKINESIA; NEUROANATOMY; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; TORSION DYSTONIA;

BRAIN; CARRIER PROTEINS; DYSTONIA MUSCULORUM DEFORMANS; FLUORODEOXYGLUCOSE F18; HUMANS; HUNTINGTON DISEASE; HYPERKINESIS; MOLECULAR CHAPERONES; NERVE NET; RADIOPHARMACEUTICALS; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0042991387     PISSN: 13507540     EISSN: None     Source Type: Journal    
DOI: 10.1097/00019052-200308000-00005     Document Type: Editorial

References (28)

1. Eidelberg D. Functional brain networks in movement disorders. Curr Opin Neurol 1998; 11:319-326.
2. Carbon M, Eidelberg D. Modulation of regional brain function by deep brain stimulation: studies with positron emission tomography. Curr Opin Neurol 2002; 15:451-455.
3. Mentis MJ, McIntosh AR, Feigin A, et al. Relationships between the metabolic patterns that correlated with mnemonic, visuospatial, and mood symptoms in Parkinson's disease. Am J Psychiatry 2002; 159:746-754.
4. Feigin A, Antonini A, Fukuda M, et al. Tc-99m ethylene cysteinate dimer SPECT in the differential diagnosis of parkinsonism. Mov Disord 2002; 17:1265-1270.
5. Carbon M, Ghilardi MF, Feigin A, et al. Learning networks in health and Parkinson's disease: reproducibility and treatment effects. Hum Brain Mapp 2003; 19:197-211.
6. Fukuda M, Ghilardi MF, Carbon M, et al. Pallidal stimulation for parkinsonism: improved brain activation during sequence learning. Ann Neurol 2002; 52:144-152.
7. Feigin A, Ghilardi MF, Carbon M, et al. Effects of levodopa on motor sequence learning in Parkinson's disease. Neurology 2003; 60:1744-1749.
8. Eidelberg D, Moeller JR, Antonini A, et al. Functional brain networks in DYT1 dystonia. Ann Neurol 1998; 44:303-312.
9. Bird TD. Penetrating observations of dystonia. Ann Neurol 1998; 44:299-300.
10. Opal P, Tinter R, Jankovic J, et al. Intrafamilial phenotypic variability of the DYT1 dystonia: from asymptomatic TOR1A gene carrier status to dystonic storm. Mov Disord 2002; 17:339-345.
11. Ozelius LJ, Hewett JW, Page CE, et al. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein. Nat Genet 1997; 17:40-48.
12. Bressman SB, deLeon D, Kramer PL, et al. Dystonia in Ashkenazic Jews: clinical characterization of a founder mutation. Ann Neurol 1994; 36:771-777.
13. Breakefield XO, Kamm C, Hanson PI. TorsinA: movement at many levels. Neuron 2001; 31:9-12.
14. Walker R, Brin M, Sandu D, et al. TorsinA immunoreactivity in brains of patients with DYT1 and non-DYT1 dystonia. Neurology 2002; 58:120-124.
15. Zeman W. Pathology of the torsion dystonias (dystonia musculorum deformans). Neurology 1970; 20:79-88.
16. Zweig RM, Hedreen JC, Jankel WR, et al. Pathology in brainstem regions of individuals with primary dystonia. Neurology 1988; 38:702-706.
17. Obeso JA, Gimenez-Roldan S. Clinicopathological correlation in symptomatic dystonia. Adv Neurol 1988; 50:113-122.
18. Konokova M, Huynh DP, Yong W, Pulst SM. Cellular distribution of torsin A and torsin B in normal human brain. Arch Neurol 2001; 58:921-927.
19. Augood SJ, Martin DM, Ozelius U, et al. Distribution of the mRNAs encoding torsinA and torsinB in the normal adult human brain. Ann Neurol 1999; 46:761-769.
20. Almasy L, Bressman SB, Raymond D, et al. Idiopathic torsion dystonia linked to chromosome 8 in two Mennonite families. Ann Neurol 1997; 42:670-673.
21. Eidelberg D, Moeller JR, Ishikawa T, et al. The metabolic topography of idiopathic torsion dystonia. Brain 1995; 118 (Pt 6):1473-1484.
22. Trost M, Carbon M, Edwards C, et al. Primary dystonia: is abnormal functional brain architecture linked to genotype? Ann Neurol 2002; 52:853-856.
23. Hutchinson M, Nakamura T, Moeller JR, et al. The metabolic topography of essential blepharospasm: a focal dystonia with general implications. Neurology 2000; 55:673-677.
24. Ghilardi M-F, Carbon M, Silvestri G, et al. Impaired sequence learning in carriers of the DYT1 dystonia mutation. Ann Neurol 2003 (in press).
25. Feigin A, Leenders KL, Moeller JR, et al. Metabolic network abnormalities in early Huntington's disease: an ((18)F)FDG PET study. J Nucl Med 2001; 42:1591-1595.
26. Feigin A, Fukuda M, Zgaljardic D, et al. Metabolic brain networks in presymptomatic Huntington's disease. Mov Disord 2001; 16:985-986.
27. Feigin A, Ma Y, Zgaljardic D, et al. PET measures of longitudinal progression in presymptomatic Huntington's disease [abstract]. Neurology 2003; 60 (Suppl. 1):A246.
28. Carbon M, Feigin A, Ghilardi M, et al. Longitudinal changes in the relationship between striatal D2 receptor binding and brain activation in preclinical Huntington's disease [abstract]. Neurology 2003; 60 (Suppl. 1):A247.