Functional activation of cerebral metabolism in mice with mutated thyroid hormone nuclear receptors

Endocrinology

Volumn 144, Issue 9, 2003, Pages 4117-4122

  Esaki, Takanori ^a   Suzuki, Hideyo ^c   Cook, Michelle ^a   Shimoji, Kazuaki ^b   Cheng, Sheue Yann ^c   Sokoloff, Louis ^a   Nunez, Jacques ^a  

^a NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

THYROID HORMONE RECEPTOR; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANTIBODY; CARBON; DEOXYGLUCOSE; DIAGNOSTIC AGENT; GLUCOSE; ISOENZYME; MICROTUBULE ASSOCIATED PROTEIN; THYROID HORMONE RECEPTOR ALPHA; THYROID HORMONE RECEPTOR BETA;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN MATURATION; BRAIN METABOLISM; CELL FUNCTION; CONGENITAL HYPOTHYROIDISM; CONTROLLED STUDY; ELECTRIC ACTIVITY; ENERGY METABOLISM; GLUCOSE UTILIZATION; IMMUNOHISTOCHEMISTRY; MOUSE; NERVE CELL DIFFERENTIATION; NEUROPIL; NONHUMAN; NORTHERN BLOTTING; PERIKARYON; PRIORITY JOURNAL; SENSORY NERVE; SPECIES COMPARISON; SPIKE WAVE; SYNAPSE VESICLE; TACTILE STIMULATION; TARGET ORGAN; VIBRISSA; WILD TYPE; ANIMAL; AUTORADIOGRAPHY; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; GENETICS; IMMUNOLOGY; METABOLISM; MOUSE MUTANT; NERVE CELL; PHYSIOLOGY; SOMATOSENSORY CORTEX; TELENCEPHALON; THALAMUS VENTRAL NUCLEUS; TRIGEMINAL NUCLEUS;

ANIMALS; ANTIBODIES; AUTORADIOGRAPHY; CARBON RADIOISOTOPES; CELL NUCLEUS; DEOXYGLUCOSE; ENERGY METABOLISM; GLUCOSE; IMMUNOHISTOCHEMISTRY; ISOENZYMES; MICE; MICE, MUTANT STRAINS; MICROTUBULE-ASSOCIATED PROTEINS; NA(+)-K(+)-EXCHANGING ATPASE; NEURONS; RECEPTORS, THYROID HORMONE; SOMATOSENSORY CORTEX; TELENCEPHALON; THYROID HORMONE RECEPTORS ALPHA; THYROID HORMONE RECEPTORS BETA; TRIGEMINAL NUCLEI; TRIGEMINAL NUCLEUS, SPINAL; VENTRAL THALAMIC NUCLEI; VIBRISSAE;

EID: 0042922456     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0414     Document Type: Article

References (30)

1. Eayrs JT 1966 Thyroid and central nervous development. In: The scientific basis of medicine annual reviews. London: Athlone; 317-339
2. Legrand J 1986 Thyroid hormone effects on growth and development. In: Hennemann G, ed. Thyroid hormone metabolism. New York: Marcel Decker; 503-534
3. Eayrs JT 1971 Thyroid and developing brain: anatomical and behavioral effects. In: Hamburgh M, Barrington EJW, eds. Hormone and development. New York: Appleton Century Crofts; 345-355
4. Morreale de EG, Ruiz-Marcos A, Escobar del RF 1983 Thyroid hormone and the developing brain. In: Dassault JH, Walker P, eds. Congenital hypothyroidism. New York: Marcel Dekker; 85-126
5. Rami A, Patel AJ, Rabie A 1986 Thyroid hormone and development of the rat hippocampus: morphological alterations in granule and pyramidal cells. Neuroscience 19:1217-1226
6. Gould E, Butcher LL 1989 Developing cholinergic basal forebrain neurons are sensitive to thyroid hormone. J Neurosci 9:3347-3358
7. Duffy TE, Cavazzuti M, Cruz NF, Sokoloff L 1982 Local cerebral glucose metabolism in new born dogs: effects of hypoxia and halothane anesthesia. Ann Neurol 11:233-246
8. Dow-Edwards D, Crane AM, Rosloff B, Kennedy C, Sokoloff L 1986 Local cerebral glucose utilization in the adult cretinous rat. Brain Res 373:139-145
9. Zhang J, Lazar MA 2000 The mechanism of thyroid hormones. Annu Rev Physiol 62:439-466
10. Kaneshige M, Suzuki H, Kaneshige K, Cheng J, Wimbrow H, Barlow C, Willingham MC, Cheng S-Y 2001 A targeted dominant negative mutation of the thyroid hormone α1 receptor causes increased mortality, infertility, and dwarfism in mice. Proc Natl Acad Sci USA 98:15095-15100
11. Kaneshige M, Kaneshige K, Zhu X-G, Dace A, Garrett L, Carter TA, Kazlauskaite R, Pankratz DG, Wynshaw-Boris A, Refetoff S, Weintraub B, Willingham MC, Barlow C, Cheng S-Y 2000 Mice with a targeted mutation in the thyroid hormone β receptor gene exhibit impaired growth and resistance to thyroid hormone. Proc Natl Acad Sci USA 97:13209-13214
12. Griffith AJ, Szymko YM, Kaneshige M, Quinonez RE, Kaneshige K, Heintz KA, Mastroianni MA, Kelley MW, Cheng SY 2002 Knock-in mouse model for resistance to thyroid hormone (RTH): an RTH mutation in the thyroid hormone receptor β gene disrupts cochlear morphogenesis. J Assoc Res Otolaryngol 3:279-88
13. Itoh Y, Esaki T, Kaneshige M, Suzuki H, Cook M, Sokoloff L, Cheng S-Y, Nunez J 2001 Brain glucose utilization in mice with a targeted mutation in the thyroid hormone α or β receptor gene. Proc Natl Acad Sci USA 98:9913-9918
14. Sokoloff L 1999 Energetics of functional activation in neural tissues. Neurochem Res 24:321-329
15. 14C]deoxyglucose method for the measurement of local cerebral glucose utilization: theory, procedure, and normal values in the conscious and anesthetized albino rat. J Neurochem 28:897-916
16. Nakao Y, Itoh Y, Kuang T-Y, Cook M, Jehle J, Sokoloff L 2001 Effects of anesthesia on functional activation of cerebral blood flow and metabolism. Proc Natl Acad Sci USA 98:7593-7598
17. Woolsey TA, Van der Loos H 1970 The structural organization of layer IV in the somatosensory region (SI) of mouse cerebral cortex. The description of a cortical field composed of discrete cytoarchitectonic units. Brain Res 17:205-242
18. Orlowski J, Lingrel JB 1988 Tissue specific and developmental regulation of rat Na,K-ATPase catalytic α isofom and β subunit mRNAs. J Biol Chem 263:10436-10442
19. Brion JP, Guilleminot J, Couchie D, Flament-Durand J, Nunez J 1988 Both adult and juvenile tau microtubule-associated proteins are axon specific in the developing and adult rat cerebellum. Neuroscience 25:139-145
20. Aniello F, Couchie D, Gripois D, Nunez J 1991 Regulation of five tubulin isotypes by thyroid hormone during brain development. J Neurochem 57:1781-1786
21. Aniello F, Couchie D, Bridoux AM, Gripois D, Nunez J 1991 Splicing of juvenile and adult tau mRNA variants is regulated by thyroid hormone. Proc Natl Acad Sci USA 88:4035-4039
22. Poddar R, Paul S, Chaudhury S, Sarkar PK 1996 Regulation of actin and tubulin gene expression by thyroid hormone during rat brain development. Mol Brain Res 35:111-118
23. Silva JE, Rudas P 1990 Effects of congenital hypothyroidism on microtubule-associated protein-2 expression in the cerebellum of the rat. Endocrinology 126:1276-1282
24. Legrand J 1967 Variations en fonction de l'age de la reponse du cervelet a l'action morphogetique de la thyroide chez le rat. Arch Anat Microsc Morphol Exp 56:291-307
25. Morte B, Manzano J, Scanlan T, Vennstrom B, Bernal J 2002 Deletion of the thyroid hormone receptor α1 prevents the structural alterations of the cerebellum induced by hypothyroidism. Proc Natl Acad Sci USA 99:3985-3989.
26. Nunez J, Couchie D, Brion JP 1988 Microtubule assembly: regulation by thyroid hormone. In: Delong GR, Robbins J, Condliffe P, eds. Iodine and the brain. New York: Plenum Press; 103-112
27. Badley DJ, Young WS, Weinberger C 1989 Differential expression of α and β thyroid hormone receptors genes in the brain and the pituitary. Proc Natl Acad Sci USA 86:7250-7254
28. Strait KA, Zou L, Oppenheimer JH 1992 β1 Isoform-specific regulation of a triiodothyronine-induced gene during cerebellar development. Mol Endocrinol 6:1874-1880
29. +-ATPase mRNA α isoforms in the developing rat brain. J Mol Neurosci 7:229-234
30. Davis PJ, Davis FB 1996 Nongenomic actions of thyroid hormone. Thyroid 6:497-504