Internal tandem duplication and Asp835 mutations of the FMS-like tyrosine kinase 3 (FLT3) gene in acute promyelocytic leukemia: Correlation with molecular subtypes of PML/RARα and clinical features

Cancer

Volumn 98, Issue 6, 2003, Pages 1206-1216

  Shih, Lee Yung ^a,b   Kuo, Ming Chung ^a   Liang, Der Cherng ^c   Huang, Chein Fuang ^a   Lin, Tung Liang ^a   Wu, Jin Hou ^a   Wang, Po Nan ^a   Dunn, Po ^a,b   Lai, Chang Liang ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b CHANG GUNG UNIVERSITY   (Taiwan)

^c MACKAY MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Acute promyelocytic leukemia; Asp835 mutation; FLT3 ITD; M3 variant; PML RAR ; S type

Indexed keywords

ASPARTIC ACID; CD135 ANTIGEN; HYBRID PROTEIN; PML RARALPHA FUSION PROTEIN TYPE L; PML RARALPHA FUSION PROTEIN TYPE S; PML RARALPHA FUSION PROTEIN TYPE V; PROTEIN TYROSINE KINASE; RETINOIC ACID RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CLINICAL FEATURE; CORRELATION ANALYSIS; CYTOGENETICS; FEMALE; FLT3 GENE; GENE AMPLIFICATION; GENE DUPLICATION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; INCIDENCE; INTERNAL TANDEM DUPLICATION; MAJOR CLINICAL STUDY; MALE; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROGNOSIS; PROMYELOCYTIC LEUKEMIA; RISK ASSESSMENT; STATISTICAL SIGNIFICANCE;

ADULT; ASPARTIC ACID; CHILD; FEMALE; FMS-LIKE TYROSINE KINASE 3; GENE DUPLICATION; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; MALE; MIDDLE AGED; MUTATION; POLYMERASE CHAIN REACTION; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; RECURRENCE; TREATMENT OUTCOME;

EID: 0042918991     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.11636     Document Type: Article

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