The ABC transporter MgAtr4 is a virulence factor of Mycosphaerella graminicola that affects colonization of substomatal cavities in wheat leaves

Molecular Plant-Microbe Interactions

Volumn 16, Issue 8, 2003, Pages 689-698

  Stergiopoulos, Ioannis ^a   Zwiers, Lute Harm ^a   De Waard, Maarten A ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Compatible interaction; Incompatible interaction; Pathogenicity; Plant defense compounds; Septoria tritici; Toxins

Indexed keywords

FUNGI; GRAMINICOLA; MYCOSPHAERELLA; MYCOSPHAERELLA GRAMINICOLA; SEPTORIA; TRITICUM AESTIVUM;

EID: 0042905955     PISSN: 08940282     EISSN: None     Source Type: Journal    
DOI: 10.1094/MPMI.2003.16.8.689     Document Type: Article

References (30)

1. Brading, P. A., Verstappen, E. C. P., Kema, G. H. J., and Brown, J. K. M. 2002. A gene-for-gene relationship between wheat and Mycosphaerella graminicola, the Septoria tritici blotch pathogen. Phytopathology 92:439-445.
2. Cohen, L., and Eyal, Z. 1993. The histology of processes associated with the infection of resistant and susceptible wheat cultivars with Septoria tritici. Plant Pathol. 42:737-743.
3. De Waard, M. A. 1997. Significance of ABC transporters in fungicide sensitivity and resistance. Pestic. Sci. 51:271-275.
4. De Wit, P. J. G. M., and Spikman, G. 1982. Evidence for the occurrence of race and cultivar-specific elicitors of necrosis in intercellular fluids of compatible interactions of Cladosporium fulvum and tomato. Physiol. Plant Pathol. 21:1-11.
5. Duncan, K. E., and Howard, R. J. 2000. Cytological analysis of wheat infection by the leaf blotch pathogen Mycosphaerella graminicola. Mycol. Res. 104:1074-1082.
6. Eyal, Z., Scharen, A. L., Prescott, J. M., and van Ginkel, M. 1987. The Septoria Diseases of Wheat: Concepts and Methods of Disease Management. International Maize and Wheat Improvement Center, Mexico City, Mexico.
7. Fleissner, A., Sopalla, C., and Weltring, K.-M. 2002. An ATP-binding cassette multidrug-resistance transporter is necessary for tolerance of Gibberella pulicaris to phytoalexins and virulence on potato tubers. Mol. Plant-Microbe Interact. 15:102-108.
8. Gisi, U., Chin, K. M., Knapova, G., Farber, R. K., Mohr, U., Parisi, S., Sierotzki, H., and Steinfeld, U. 2000. Recent developments in elucidating modes of resistance to phenylamide, DMI and strobilurin fungicides. Crop Prot. 19:863-872.
9. Heath, M. C. 1971. Haustorial sheath formation in cowpea leaves immune to rust infection. Phytopathology 61:383-388.
10. Higgins, C. F. 1992. ABC transporters: From microorganisms to man. Annu. Rev. Cell. Biol. 8:67-113.
11. Kalb, V. F., Woods, C. W., Turi, T. G., Dey, C. R., Sutter, T. R., and Loper, J. C. 1987. Primary structure of the P450 lanosterol demethylase gene from Saccharomyces cerevisiae. DNA 6:529-537.
12. Kema, G. H. J., and Van Silfhout, C. H. 1997. Genetic variation for virulence and resistance in the wheat-Mycosphaerella graminicola pathosystem III. Comparative seedling and adult plant experiments. Phytopathology 87:266-272.
13. Kema, G. H. J., Yu, D., Rijkenberg, F. H. J., Shaw, M. W., and Baayen, R. P. 1996. Histology of the pathogenesis of Mycosphaerella graminicola in wheat. Phytopathology 86:777-786.
14. Kema, G. H. J., Verstappen, E. C. P., and Waalwijk, C. 2000. Avirulence in the wheat Septoria tritici leaf blotch fungus Mycosphaerella graminicola is controlled by a single locus. Mol. Plant-Microbe Interact. 13:1375-1379.
15. Nelson, L. R., and Marshall, D. 1990. Breeding wheat for resistance to Septoria nodorum and Septoria tritici. Adv. Agron. 44:257-277.
16. Payne, A. C., GrosjeanCournoyer, M. C., and Hollomon, D. W. 1998. Transformation of the phytopathogen Mycosphaerella graminicola to carbendazim and hygromycin B resistance. Curr. Genet. 34 (2): 100-104.
17. Perrone, G., Logrieco, A., Kema, G. J. H., Ritieni, A., and Bottalico, A. 1999. Phytotoxic activity of Mycosphaerella graminicola culture filtrates. Pages 39-45 in: Vol. 6 Proceedings of Phytosfere 1999, Rome, Italy.
18. Pinkerton, F., and Strobel, G. 1976. Serinol as an activator of toxin production in attenuated cultures of Helminthosporium sacchari (Eyespot disease of sugarcane). Proc. Natl. Acad. Sci. U.S.A. 73:4007-4011.
19. Pnini-Cohen, S., Zilberstein, A., Schuster, S., Sharon, A., and Eyal, Z. 1997. The expression of the uidA reporter gene and virulence in transformants of Septoria tritici. Page 60 in: Proceedings of the 15th Long Ashton International Symposium on Understanding Pathosystems: A Focus on Septoria. Long Ashton, U.K.
20. Schoonbeek, H.-J., Del Sorbo, G., and De Waard, M. A. 2001. The ABC transporter BcatrB affects the sensitivity of Botrytis cinerea to the phytoalexin resveratrol and the fungicide fenpiclonil. Mol. Plant-Microbe Interact. 14:562-571.
21. Schoonbeek, H., Raaijmakers, J. M., and De Waard, M. A. 2002. Fungal ABC transporters and microbial interactions in natural environments. Mol. Plant-Microbe Interact. 15:1165-1172.
22. Shaner, G., Stromberg, E. L., Lacy, G. H., Barker, K. R., and Pirone, T. P. 1992. Nomenclature and concepts of pathogenicity and virulence. Annu. Rev. Phytopathol. 30:47-66.
23. Shetty, N. P., and Jorgensen, N. J. L. 2001. Histochemical studies of defence responses of wheat against Septoria tritici. Abst. no. 433. Proceedings of the 10th International Congress on Molecular Plant- Microbe Interactions, Madison, WI, U.S.A.
24. Stergiopoulos, I., Gielkens, M. M., Goodall, S. D., Venema, K., and De Waard, M. A. 2002a. Molecular cloning and characterisation of three new ATP-binding cassette transporter genes from the wheat pathogen Mycosphaerella graminicola. Gene 289:141-149.
25. Stergiopoulos, I., Zwiers, L.-H., and De Waard M. A. 2002b. Secretion of natural and synthetic toxic compounds from filamentous fungi by membrane transporters of the ATP-binding cassette and major facilitator superfamily. Eur. J. Plant Pathol. 108:719-734.
26. Urban, M., Bhargava, T., and Hamer, J. E. 1999. An ATP-driven efflux pump is a novel pathogenicity factor in rice blast disease. EMBO (Eur. Mol. Biol. Organ.) J. 18:512-521.
27. Wilson, U. E., and Coffey, M. D. 1980. Cytological evaluation of general resistance to Phytophthora infestans (late blight) in potato foliage. Ann. Bot. 45:81-90.
28. Zwiers, L.-H., and De Waard, M. A. 2000. Characterization of the ABC transporter genes MgAtr1 and MgAtr2 from the wheat pathogen Mycosphaerella graminicola. Fun. Gen. Biol. 30:115-125.
29. Zwiers, L.-H., and De Waard, M. A. 2001. Efficient Agrobacterium tumefaciens-mediated gene disruption in the phytopathogen Mycosphaerella graminicola. Curr. Genet. 39:388-393.
30. Zwiers, L. H., Stergiopoulos, I., Gielkens, M. M. C., Goodall, S. D., and De "Waard, M. A. ABC transporters of the wheat pathogen Mycosphaerella graminicola function as protectants against biotic and xenobiotic compounds. Mol. Gen. Genet., in press.