Current dilemmas in postnatal steroid therapy for chronic lung disease in preterm infants

Biology of the Neonate

Volumn 84, Issue 1, 2003, Pages 96-100

  Shinwell, Eric S ^a,b  

^a KAPLAN MEDICAL CENTER   (Israel)

^b HEBREW UNIVERSITY OF JERUSALEM   (Israel)

Author keywords

Bronchopulmonary dysplasia; Cerebral palsy; Clinical trials; Corticosteroids; Dexamethasone; Meta analysis; Neurodevelopmental disability

Indexed keywords

CORTICOSTEROID; DEXAMETHASONE;

CEREBRAL PALSY; CHRONIC DISEASE; CHRONIC LUNG DISEASE; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED CLINICAL TRIAL; CORTICOSTEROID THERAPY; GASTROINTESTINAL HEMORRHAGE; GROWTH DISORDER; HUMAN; HYPERGLYCEMIA; HYPERTENSION; HYPERTROPHIC CARDIOMYOPATHY; INTESTINE PERFORATION; LUNG DISEASE; META ANALYSIS; NEWBORN; POSTNATAL CARE; PRACTICE GUIDELINE; PREMATURITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; RISK BENEFIT ANALYSIS; VERY LOW BIRTH WEIGHT;

ADRENAL CORTEX HORMONES; CHRONIC DISEASE; DEXAMETHASONE; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; INFANT, VERY LOW BIRTH WEIGHT; LUNG DISEASES; PRACTICE GUIDELINES; RANDOMIZED CONTROLLED TRIALS; RISK ASSESSMENT;

EID: 0042905932     PISSN: 00063126     EISSN: None     Source Type: Journal    
DOI: 10.1159/000071011     Document Type: Conference Paper

References (40)

1. Avery ME, Mead J: Surface properties in relation to atelectasis and hyaline membrane disease. Am J Dis Child 1959;97:517-523.
2. Buckingham S, McNary W, Sommers S, Rothschild J: Is lung an analog of Moog's developing intestine? I. Phosphatases and pulmonary alveolar differentiation in fetal rabbits (abstract). Fed Proc 1968;27:328.
3. Liggins GC: Premature delivery of fetal lambs infused with glucocorticoids. J Endocrinol 1969;45:515-523.
4. Haddad H, Hsia D, Gellis S: Studies on respiratory rate in the newborn. Its use in the evaluation of RDS in IDM. Pediatrics 1956;17:204-213.
5. Altman H: The respiratory distress syndrome of the newborn. A report of 135 cases treated conservatively. S Afr Med J 1965;39:746-748.
6. Ewerbeck H, Helwig H: Treatment of idiopathic respiratory distress with large doses of corticoids. Pediatrics 1972;49:467-468.
7. Baden M, Bauer CR, Colle E, Klein G, Taeusch HW, Stern L: A controlled trial of hydrocortisone therapy in infants with respiratory distress syndrome. Pediatrics 1972;50:526-534.
8. Taeusch HW, Wang NS, Baden M, Bauer CR, Stern L: A controlled trial of hydrocortisone therapy in infants with respiratory distress syndrome. II. Pathology. Pediatrics 1973;52:850-854.
9. Fitzhardinge PM, Eisen A, Lejtenyi C, Metrakos K, Ramsay M: Sequelae of early steroid administration to the newborn infant. Pediatrics 1974;53:877-883.
10. Ogden BE, Murphy SA, Saunders GC, Pathak D, Johnson JD: Neonatal lung neutrophils and elastase/proteinase inhibitor imbalance. Am Rev Respir Dis 1984;130:817-821.
11. Merritt TA, Stuard ID, Puccia J, Wood B, Edwards DK, Finkelstein J, Shapiro DL: Newborn tracheal aspirate cytology: Classification during respiratory distress syndrome and bronchopulmonary dysplasia. J Pediatr 1981;98:949-956.
12. Halliday HL, Ehrenkranz RA, Doyle LW: Early postnatal (<96 h) corticosteroids for preventing chronic lung disease in preterm infants. Oxford, The Cochrane Library, 2003, Issue 1, Update Software.
13. Halliday HL, Ehrenkranz RA, Doyle LW: Moderately early postnatal (7-14 days) cortico-steroids for preventing chronic lung disease in preterm infants. Oxford, The Cochrane Library, 2003, Issue 1, Update Software.
14. Halliday HL, Ehrenkranz RA, Doyle LW: Delayed (>3 weeks) corticosteroids for chronic lung disease in preterm infants. Oxford, The Cochrane Library, 2003, Issue 1, Update Software.
15. Shinwell ES, Karplus M, Reich D, Weintraub Z, Blazer S, Bader D, Yurman S, Dolfin T, Kogan A, Dollberg S, Arbel E, Goldberg M, Gur I, Naor N, Sirota L, Mogilner S, Zaritsky A, Barak M, Gottfried S: Early postnatal dexamethasone treatment and increased incidence of cerebral palsy. Arch Dis Child Fetal Neonatal Ed 2000;83:F177-F181.
16. O'Shea TM, Kothadia JM, Klinepeter KL, Goldstein DJ, Jackson BG, Weaver RG, Dillard RG: Randomized placebo-controlled trial of a 42-day tapering course of dexamethasone to reduce the duration of ventilator dependency in very low birth weight infants: Outcome of study participants at 1-year adjusted age. Pediatrics 1999;104:15-21.
17. Yeh TF, Lin YJ, Huang CC, Chen YJ, Tsai WF, Lien YJ: Early postnatal (<12 h) dexa-methasone therapy for prevention of BPD in preterm infants with RDS - A two-year follow-up study. Pediatrics 1998;101:E7.
18. Halliday HL, Ehrenkranz RA: Early postnatal (<96 h) corticosteroids for preventing chronic lung disease in preterm infants (Cochrane Review). Oxford, The Cochrane Library, 1998, Update Software.
19. Halliday HL, Ehrenkranz RA: Moderately early postnatal (7-14 days) corticosteroids for preventing chronic lung disease in preterm infants (Cochrane Review). Oxford, The Cochrane Library, 1998, Update Software.
20. Halliday HL, Ehrenkranz RA: Delayed (>3 weeks) corticosteroids for preventing chronic lung disease in preterm infants (Cochrane Review). Oxford, The Cochrane Library, 1998, Update Software.
21. Bhuta T, Ohlsson A: Systematic review and meta-analysis of early postnatal dexamethasone for prevention of chronic lung disease. Arch Dis Child Fetal Neonatal Ed 1998;79:F26-F33.
22. Doyle LW, Davis P: Review article: Postnatal corticosteroids in preterm infants: Systematic review of effects on mortality and motor function. J Paediatr Child Health 2000;36:101-107.
23. American Academy of Pediatrics Committee on Fetus and Newborn: Postnatal corticoste-roids to treat or prevent chronic lung disease in preterm infants. Pediatrics 2002;109:330-338.
24. Flagel SB, Vazquez DM, Watson SJ, Neal CR: Effects of tapering neonatal dexamethasone on rat growth, neurodevelopment and stress response. Am J Physiol 2002;282:R55-R63.
25. Bloomfield FH, Knight DB, Breier BH, Harding JE: Growth restriction in dexamethasone-treated preterm infants may be mediated by reduced IGF-1 and IGFBP-3 plasma concentrations. Clin Endocrinol 2001;54:235-242.
26. Murphy BP, Inder TE, Huppi PS, Warfield S, Zientara GP Kikinis R, Jolesz FA, Volpe JJ: Impaired cerebral cortical grey matter growth after treatment with dexamethasone for neonatal chronic lung disease. Pediatrics 2001;107:217-221.
27. Edwards AD: Cerebral white matter damage in very preterm infants. Biol Neonate 2002;82:292-293.
28. Weichsel ME: The therapeutic use of glucocorticoid hormones in the perinatal period: Potential neurologic hazards. Ann Neurol 1977;2:364-366.
29. Vincedomini JP, Nonneman AJ, DeKosky ST, Scheff SW: Perinatal glucocorticoids disrupt learning: A sexually-dimorphic response. Physiol Behav 1986;36:145-149.
30. Gould E: The effects of adrenal steroids and excitatory input on neuronal birth and survival. Ann NY Acad Sci 1994;743:73-92.
31. Sysyn GD, Petersson KH, Patlak CS, Sadowska GB, Stonestreet BS: Effects of postnatal dexamethasone on blood-brain barrier permeability and brain water content in newborn lambs. Am J Physiol 2001;280:R547-R553.
32. Ferguson SA, Holson RR: Neonatal dexamethasone on day 7 causes mild hyperactivity and cerebellar stunting. Neurotoxicol Teratol 1999;21:71-76.
33. McGowan JE, Sysyn G, Petersson KH, Sadowska GB, Mishra OP, Delivoria-Papadopoulos M, Stonestreet BS: Effect of dexamethasone treatment on maturational changes in the NMDA receptor in sheep brain. J Neurosci 2000;20:7424-7429.
34. Jacobs HC, Chapman RL, Gross I: Premature conclusions on postnatal steroid effects. Pediatrics 2002;110:200-201.
35. Durand M, Mendoza ME, Tantivit P, Kugelman A, McEvoy C: A randomized trial of moderately early low dose dexamethasone therapy in very low birth weight infants: Dynamic pulmonary mechanics, oxygenation and ventilation. Pediatrics 2002;109:262-268.
36. Watterberg KL, Gerdes JS, Gifford KL, Lin HM: Prophylaxis against early adrenal insufficiency to prevent chronic lung disease in premature infants. Pediatrics 1999;104:1258-1263.
37. Decastro MH, LaGamma EF: Postnatal use of betamethasone vs. dexamethasone for treatment of evolving BPD in extremely low birth weight neonates (abstract). Pediatr Res 2002;2069.
38. Lister P, Iles R, Shaw B, Ducharme F: Inhaled steroids for neonatal chronic lung disease (Cochrane Review). Oxford, The Cochrane Library, 2002, Issue 2, Update Software.
39. Burchfield DJ: Postnatal steroids to treat or prevent chronic lung disease in preterm infants. Pediatrics 2003;111:221-222.
40. Blackmon LR, Barrington KJ: Reply to reference 39. Pediatrics 2003;111:222.