Abundant PrPCWD in tonsil from mule deer with preclinical chronic wasting disease

Journal of Veterinary Diagnostic Investigation

Volumn 15, Issue 4, 2003, Pages 320-323

  O'Rourke, Katherine I ^a   Zhuang, Dongyue ^b   Lyda, Amy ^a   Gomez, Gabriel ^a   Williams, Elizabeth S ^c   Tuo, Wenbin ^a   Miller, Michael W ^d  

^a AGRICULTURAL RESEARCH SERVICE   (United States)

^b WASHINGTON STATE UNIVERSITY   (United States)

^c UNIVERSITY OF WYOMING   (United States)

^d Colorado Division of Wildlife ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CERVIDAE; ODOCOILEUS HEMIONUS;

DIAGNOSTIC AGENT; MONOCLONAL ANTIBODY;

ANIMAL; ANIMAL DISEASE; ARTICLE; CALIBRATION; CHEMISTRY; DEER; IMMUNOASSAY; MICROBIOLOGY; PATHOLOGY; PRION; PRION DISEASE; SENSITIVITY AND SPECIFICITY; TONSIL; WASTING SYNDROME;

ANIMALS; ANTIBODIES, MONOCLONAL; CALIBRATION; DEER; IMMUNOASSAY; PRION DISEASES; PRIONS; SENSITIVITY AND SPECIFICITY; TONSIL; WASTING SYNDROME;

EID: 0042885555     PISSN: 10406387     EISSN: None     Source Type: Journal    
DOI: 10.1177/104063870301500403     Document Type: Article

References (11)

1. Biffiger K, Zwald D, Kaufmann L, et al.: 2002, Validation of a luminescence immunoassay for the detection of PrPSc in brain homogenate. J Virol Methods 101:79-84.
2. Grassi J, Comoy E, Simon S, et al.: 2001, Rapid test for the preclinical postmortem diagnosis of BSE in central nervous system tissue. Vet Rec 149:577-582.
3. Guiroy DC, Williams ES, Yanagihara R, et al.: 1991, Immunolocalization of scrapie amyloid (PrP27-30) in chronic wasting disease of Rocky Mountain elk and hybrids of captive mule deer and white-tailed deer. Neurosci Lett 126:195-198.
4. Miller MW, Williams ES: 2002, Detecting PrP-CWD in mule deer by immunohistochemistry of lymphoid tissues. Vet Rec 151:610-613.
5. O'Rourke KI, Baszler TV, Besser TE, et al.: 2000, Preclinical diagnosis of scrapie by immunohistochemistry of third eyelid lymphoid tissue. J Clin Microbiol 38:3254-3259.
6. O'Rourke KI, Baszler TV, Miller JM, et al.: 1998, Monoclonal antibody F89/160.1.5 defines a conserved epitope on the ruminant prion protein. J Clin Microbiol 36:1750-1755.
7. Sc detection and its use as a rapid surveillance method for the diagnosis of bovine spongiform encephalopathy (BSE). Acta Neuropathol (Berl) 98:437-443.
8. Sigurdson CJ, Williams ES, Miller MW, et al.: 1999, Oral transmission and early lymphoid tropism of chronic wasting disease PrPres in mule deer fawns (Odocoileus hemionus). J Gen Virol 80:2757-2764.
9. Spraker TR, O'Rourke KI, Balachandran A, et al.: 2002, Validation of monoclonal antibody F99/97.6.1 for immunohistochemical staining of brain and tonsil in mule deer (Odocoileus hemionus) with chronic wasting disease. J Vet Diagn Invest 14: 3-7.
10. Williams ES, Miller MW: 2002, Chronic wasting disease in deer and elk in North America. Revue Sci Tech O I E 21: 305-316.
11. Williams ES, Young S: 1980, Chronic wasting disease of captive mule deer: a spongiform encephalopathy. J Wildlf Dis 16:89-98.