Effect of recombinant prothymosin α on secretion of IFN-γ, IFN-α and TNF-α in vitro

Yaoxue Xuebao

Volumn 37, Issue 5, 2002, Pages 326-328

  Qiu, Lei ^a   Guo, Bao Yu ^a   Miao, Hong ^a   Dao, Shu Yan ^a   Zhang, Ran ^a   Yuan, Peng Qun ^a   Yang, Xu ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Cytokine; Immunoregulate; Prothymosin

Indexed keywords

ALPHA INTERFERON; DRUG DERIVATIVE; GAMMA INTERFERON; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; IMMUNOLOGICAL ADJUVANT; PROTEIN PRECURSOR; PROTHYMOSIN ALPHA; THYMOSIN; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL; ARTICLE; BAGG ALBINO MOUSE; CELL SEPARATION; CYTOLOGY; DRUG EFFECT; FEMALE; LYMPHOCYTE; MACROPHAGE; MOUSE; PERITONEUM MACROPHAGE; SECRETION; SPLEEN;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; CELL SEPARATION; FEMALE; GLUTATHIONE TRANSFERASE; INTERFERON TYPE II; INTERFERON-ALPHA; LYMPHOCYTES; MACROPHAGES; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED BALB C; PROTEIN PRECURSORS; RECOMBINANT FUSION PROTEINS; SPLEEN; THYMOSIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0042884114     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (4)

1. Evstafieva AC, Chichkova NV, Makarova TN, et al. Overproduction in Escherichia coli. purification and properties of human prothymosin α [J]. Eur J Biochem, 1995,231(3): 639-643.
2. Smith MR. Prothymosin α: in search of function [J]. Leuk Lymph, 1995,18(3-4):209-214.
3. Eckert K, Grunberg E, Garbin F, et al. Preclinical studies with prothymosin alpha on mononuclear cells from tumor patients [J]. Int J Immunopharmacol, 1997,19(9-10): 493-500.
4. Zavlyalov VP, Navolotskaya EN, Vasilenko RN, et al. The sequence 130 ∼ 137 of human interferon-α-2 is involved in the competition of interferon, prothymosin alpha and cholera toxin B subunit for common receptors on human fibroblasts [J]. Mol Immunol, 1995,32(6):425-431.