Application of supercritical fluid technology in the formation of microparticulate powders of antibiotics

Chinese Journal of Antibiotics

Volumn 28, Issue 8, 2003, Pages 506-510

  Zhu, Zi Qiang ^a   Guan, Yi Xin ^a  

^a ZHEJIANG UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; SOLVENT;

DRUG SYNTHESIS; PARTICLE SIZE; POWDER; PRECIPITATION; REVIEW; SUPERCRITICAL FLUID EXTRACTION;

EID: 0042878361     PISSN: 10018689     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (8)

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2. Gordillo M D, Blanco M A, Molero A, et al. Solubility of the antibiotic penicillin G in supercritical carbon dioxide [J]. J Supercrit Fluids, 1999,15:183
3. 2[J]. J Supercrit Fluids, 1991,4:32
4. 3[J]. Ind Eng Chem Res, 1995,34:4087
5. Jouyban A, Chan H D, Foster N R, Mathematical representation of solute solubility in supercritical carbon dioxide using empirical expressions [J]. J Supercrit Fluids, 2002, 24:19
6. Reverchon E, Porta G D. Production of antibiotic micro- and nano-particles by supercritical antisolvent precipitation [J]. Powder Technol, 1999,106:23
7. Reverchon E, Porta G D, Falivene M G. Process parameter and morphology in amoxicillin micro and submicro particles generation by supercritical antisolvent precipitations [J]. J Supercrit Fluids, 2000,17:239