In vitro radiation-induced effects on rat tracheal epithelial cells: I) Different radiosensitivity of cell inactivation after α and γ irradiations

Journal of Radiation Research

Volumn 43, Issue 1, 2002, Pages 27-34

  Kugel, Carole ^a   Bailly, Isabelle ^a   Tourdes, Françoise ^a   Poncy, Jean Luc ^a  

^a CEA DIF   (France)

Author keywords

Alpha particles; Epithelial cells; Gamma rays; In vitro; Radiosensitivity

Indexed keywords

ALPHA PARTICLES; CELLS; CYTOLOGY; EXPONENTIAL FUNCTIONS; IRRADIATION; RADIATION EFFECTS; RATS;

CELL-BE; CELL/B.E; CELL/BE; EPITHELIAL CELLS; GAMMA-RAYS; IN-VITRO; RADIOSENSITIVITY; RAT CELLS; RAT STRAINS; SPRAGUE-DAWLEY;

GAMMA RAYS;

MARTES PENNANTI;

ALPHA RADIATION; ANIMAL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CYTOLOGY; EPITHELIUM CELL; FISCHER 344 RAT; GAMMA RADIATION; LINEAR ENERGY TRANSFER; RADIATION DOSE; RADIATION EXPOSURE; RAT; SPRAGUE DAWLEY RAT; TRACHEA;

ALPHA PARTICLES; ANIMALS; CELL SURVIVAL; CELLS, CULTURED; EPITHELIAL CELLS; GAMMA RAYS; LINEAR ENERGY TRANSFER; RADIATION TOLERANCE; RATS; RATS, INBRED F344; RATS, SPRAGUE-DAWLEY; TRACHEA;

EID: 0042871530     PISSN: 04493060     EISSN: None     Source Type: Journal    
DOI: 10.1269/jrr.43.27     Document Type: Article

References (34)

1. James, A. C., Gehr, P., Masse, R., Cuddihy, R. G., Cross, F. T., Birchall, A., Durham, J. S. and Briant, J. K. (1991) Dosimetry model for bronchial and extrathoracic tissue of the respiratory tract. Radiat. Prot. Dos., 37: 221-230.
2. Tokarskaya, Z. B., Okladnikova, N. D., Belyaeva, Z. D. and Drozhko, E. G. (1997) Multifactorial analysis of lung cancer dose-response relationships for workers at Mayac nuclear enterprise. Health Phys., 73: 899-905.
3. Koshurnikova, N. A., Bolotnikova, M. G., Ilyin, L. A., Keirim-Markus, I. B., Menshikh, Z. S., Okatenko, P. V., Romanov, S. A., Tsvetkov, V. I. and Shilnikova, N. S. (1998) Lung cancer risk due to exposure to incorporated plutonium. Radiat. Res., 189: 366-371.
4. Kreisheimer, M., Koshurnikova, N. A. Nekolla, E., Khokhryakov, V. F., Romanov, S. A., Sokolnikov, M. E., Shilnikova, N.S., Okatnko, P. V. and Kellerer, A. M. (2000) Lung cancer mortality among male nuclear workers of the Mayak facilities in the former Soviet Union. Radiat. Res. 154: 3-11.
5. Barendsen, G. W., Beusker, T. L. J., Vergroesen, A. J. and Budke, L. (1960a) Effect of different ionizing radiations on human cells in tissue culture. I. Irradiation techniques and dosimetry. Radiat. Res. 13: 832-840.
6. Barendsen, G. W., Beusker, T. L. J., Vergroesen, A. J. and Budke, L. (1960b) Effect of different ionizing radiations on human cells in tissue culture. II. Biological Experiments. Radiat. Res. 13: 841-849.
7. Loyd, E. L., Gemmel, M. A., Henning, G. B., Gemmel, D. S. and Zabransky, B. J. (1979) Transformation of mammalian cells by alpha Particles. Int. J. Radiat. Biol. 36: 476-478.
8. Hall, E. J. and Hei, T. K. (1985) Oncogenic transformation in Vitro by radiation at varying LET. Radiat. Prot. Dos. 13: 139-151.
9. Roberts, C. J. and Goodhead, D. T. (1987) The effect of 238Pu α-particles on the mouse fibroblast cell line C3H10T1/2: Characterisation of source and RBE for cell survival. Int. J; Radiat. Biol. 52: 871-882.
10. Bettega, D., Calzolari, P., Chiorda, G. N. and Tallone-Lombardi, L. (1992) Transformation of C3H 10T1/2 cells with 4.3 MeV α particles at low doses: Effects of single and fractionated doses. Radiat. Res. 131: 66-71.
11. Roberston, J. B., Koehler, A., George, J. and Little, J. B. (1983) Oncogenic transformation of mouse Balb/3T3 cells by Plutonium-238 α-particles. Radiat. Res. 96: 261-274.
12. Yang, T. C., Gruenert, D. C., Holley, W. R. and Curtis, S. B. (1990) Response of cultured human airway epithelial cells to X-rays and energetic a-particles. Int. J. Radiat.Biol. 58: 509-517.
13. Thomassen, D. G., Seiler, F. A., Shyr, L. -J. and Griffith, W. C. (1990) Alpha-particles induce preneoplastic transformation of rat tracheal epithelial cells in culture. Int. J. Radiat.Biol. 57: 395-405.
14. 210Po alpha particles on survival and preneoplastic transformation of primary rat tracheal epithelial cells irradiated while in suspension or in the intact tissue. Radiat. Res. 136: 89-96.
15. Terzaghi-Howe M. (1989) Induction of preneoplastic alterations by X-rays and neutrons in exposed rat tracheas and isolated tracheal epithelial cells. Radiat Res. 120: 352-363.
16. Schwartz, J. L., Rotmensch, J., Atcher, R. W., Jostes, R. F., Cross, F. T., Hui, T. E., Chen, D., Carpenter, S., Evans, H. H., Mencl, J., Bakale, G. and Rao, P. S. (1992) Interlaboratory comparison of different alpha-particle and radon sources: cell survival and relative biological effectiveness. Heath Phys. 62: 458-461.
17. Lambin, P., Malaise, E. P. and Joiner, M. C. (1996) Might intrinsic radioresistance of human tumour cells be induced by radiation ?. Int. J. Radiat.Biol. 69: 279-290.
18. Bao, S., Harwood, P. W., Wood, B. H., Chrisler, W. B., Groch, K. M. and Brooks, A. L. (1997) Comparative clastogenic sensitivity of respiratory tract cells to gamma rays. Radiat. Res. 148: 90-97
19. Cartwright, B. G., Shirk, E. K. and Price, P. B. (1978) A nuclear track recording polymer of unique sensitivity and resolution. Nucl. Instrum. Methods 153: 457-460.
20. Bailly-Despiney, I., Poncy, J. L., Jouanny, F., Lagroye, I., Lizon, C., Massiot, P., Leffol, L. and Fritsch, P. (1997) Investigations on death process in rat epithelial cells exposed to alpha irradiation in vitro. Radioprotection 32: C1-375.
21. Bailly, I., Champion, C., Massior, P., Savarin, P., Poncy, J.-L., Crespin, S., Alloy, G., Jacob, V., Peritbon, E. (2002) Development of an experimental system for biological studies: Scintillation and solid-track detectors as dose monitors. Nucl. Instrum. Methods B, 187: 137-148.
22. Raju, M. R., Eisen, Y., Carpenter, S., Jarrett, K. and Harvey, W. F. (1993) Radiobiology of α particles. IV. Cell inactivation by α particles of energies 0.4-3.5 MeV. Radiat. Res. 133: 289-296.
23. Han, Z-B., Suzuki, H., Suzuki, F., Suzuki, M., Furusawa, Y., Kato, T. and Ikenaga M. (1998) Relative biological effectiveness of accelerated heavy ions for induction of morphological transformation in Syrian hamster embryo cells. J. Radiat. Res. 39: 193-201.
24. Barendsen, G. W. (1994) RBE ñ LET relationships for different types of lethal radiation damage in mammalian cells : comparison with DNA dsh and an interpretation of differences in radiosensitivity. Int. J. Radiat. Biol. 66: 433-436.
25. Raju, M. R., Eisen, Y., Carpenter, S. and Inkret, W. C. (1991) Radiobiology of α particles. III. Cell inactivation by α particle traversals of the cell nucleus. Radiat. Res. 128: 204-209.
26. Stinchcomb, T. G. and Roeske, J. C. (1995) Survival of alpha particle irradiated cells as a function of the shape and the size of the sensitive volume (nucleus). Radiat. Prot. Dos. 62: 157-164.
27. Cole, A., Meyn, R. E., Chen, R., Corry, P. M. and Hittelman, W. (1980) Mechanisms of cell injury. In Radiation Biology in Cancer Research, Eds. R. E. Meyn and H. R. Withers, pp 33-58, Raven Press, New York.
28. Miller, R. C., Randers-Pehrson, G., Geard, C. R., Hall, E. J. and Brenner, D. J. (1999) The oncogenic transforming potential of the passage of single α particles through mammalian cell nuclei, PNAS 96: 19-22.
29. Wu, L. J., Randers-Pehrson, G., Xu, A., Waldren, C. A., Geard, C. R., Yu, Z. L. and Hei T. K. (1999) Targeted cytoplasmic irradiation with alpha particles induces mutations in mammalian cells. PNAS 96: 4959-4964.
30. Simmons, J. A., Cohn, P. and Min, T. (1996) Survival and yields of chromosome aberrations in hamster and human lung cells irradiated by alpha particles. Radiat. Res. 145: 174-180.
31. Brooks, A. L., Bao, S., Harwood, P. W., Wood, B. H., Chrisler W. B., Khan M. A., Gies R. A. and Cross F. T. (1997) Induction of micronuclei in respiratory tract following radon inhalation. Int. J. Radiat. Biol. 72: 485-495.
32. Barendsen, G. W. (1964) Impairment of the proliferative capacity of human cells in culture by alpha particles with differing linear-energy transfer. Int. J. Radiat. Biol. 8: 453-466.
33. 238Pu α-particles on the mouse fibroblast cell line C3H 10T1/2 : characterization of source and RBE for cell survival. Int. J. Radiat. Biol. 52: 871-882.
34. Kahn, M. A., Cross, F. T., Buschbom, R. L., Brooks, A. L. (1995) Inhaled radon-induced genotoxicity in Wistar rat, Syrian hamster and Chinese hamster deep-lung fibroblasts in vivo. Mutat. Res. 334: 131-137.