Characterization of Ca2+ channels and G proteins involved in arachidonic acid release by endothelin-1/endothelinA receptor

Molecular Pharmacology

Volumn 64, Issue 3, 2003, Pages 689-695

  Kawanabe, Yoshifumi ^a,b   Nozaki, Kazuhiko ^a   Hashimoto, Nobuo ^a   Masaki, Tomoh ^a  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (4 METHOXYPHENYL) 2 [3 (4 METHOXYPHENYL)PROPOXY]ETHYL] 1H IMIDAZOLE; 2 (3,4 DIHYDRO 6,7 DIMETHOXY 1 ISOQUINOLINYL) 2 PHENYL N,N BIS[2 (2,3,4 TRIMETHOXYPHENYL)ETHYL]ACETAMIDE; 2 MORPHOLINO 8 PHENYLCHROMONE; ARACHIDONIC ACID; CALCIUM CHANNEL; ENDOTHELIN 1; ENDOTHELIN A RECEPTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; WORTMANNIN; ENDOTHELIN RECEPTOR;

ANIMAL CELL; ARACHIDONIC ACID METABOLISM; ARTICLE; CALCIUM TRANSPORT; CARBOXY TERMINAL SEQUENCE; CHO CELL; IC 50; NONHUMAN; PALMITOYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; ANIMAL; CHEMISTRY; DOSE RESPONSE; DRUG POTENTIATION; HAMSTER; METABOLISM; PHYSIOLOGY; SECRETION;

ANIMALS; ARACHIDONIC ACID; CALCIUM CHANNELS; CHO CELLS; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIN-1; GTP-BINDING PROTEINS; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN;

EID: 0042856417     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.64.3.689     Document Type: Article

References (24)

1. 2-mediated release of arachidonic acid is critical for proliferation of vascular smooth muscle cells. J Biol Chem 272:30504-30511.
2. Arai H, Hori S, Aramori I, Ohkubo H, and Nakanishi S (1990) Cloning and expression of a cDNA encoding an endothelin receptor. Nature (Lond) 348:730-732.
3. Aramori I and Nakanishi S (1992) Coupling of two endothelin receptor subtypes to differing signal transduction in transfected Chinese hamster ovary cells. J Biol Chem 267:12468-12474.
4. 2+ current in guinea-pig ventricular myocytes mediated by Gbeta-gamma-dependent activation of adenylyl cyclage. J Physiol (Lond) 536:677-692.
5. Dennis EA (1997) The growing phospholipase A2 superfamily of signal transduction enzymes. Trends Biochem Sci 22:1-2.
6. 12 stimulates cell proliferation through cycloxygenase-2 signaling pathway. Oncogene 18:7185-7189.
7. Gong MC, Kinter MT, Somlyo AV, Somlyo AP (1995) Arachidonic acid and diacylglycerol release associated with inhibition of myogin light chain dephosphorilation in rabbit smooth muscle. J Physiol (Lond) 486:113-122.
8. A receptor. Mol Pharmacol 62:756-761.
9. 2+ channels activated by endothelin-1 in CHO cells expressing endothelin-A or endothelin-Breceptors. Am J Physiol 281:C1676-C1685.
10. A receptors. Mol Pharmacol 62:75-80.
11. A receptor. Mol Pharmacol 61:277-284.
12. 2). FEBS Lett 410:49-53.
13. Leslie CC (1997) Properties and regulation of cytosolic phospholipase A2. J Biol Chem 272:16709-16712.
14. Lin LL, Lin AY, and Knopf JL (1992) Cytosolic phospholipase A2 is coupled to hormonally regulated release of arachidonic acid. Proc Natl Acad Sci USA 89: 6147-6151.
15. Perez DM, DeYoung MB, and Graham RM (1993) Coupling of expressed α1B- and α1D-adrenergic receptor to multiple signaling pathways is both G protein and cell type specific. Mol Pharmacol 44:784-795.
16. Roshak A, Sathe G, and Marshall LA (1994) Suppression of monocyte 85-kDa phospholipase A2 by antisense and effects on endotoxin-induced prostaglandin biosynthesis. J Biol Chem 269:25999-26005.
17. Sakurai T, Yanagisawa M, Takuwa Y, Miyazaki H, Kimura S, Goto K, and Masaki T (1990) Cloning of cDNA encoding a non-isopeptide-selective subtype of the endothelin receptor. Nature (Lond) 348:732-735.
18. Silfani TN and Freeman EJ (2002) Phosphatidylinositide 3-kinase regulates angiotensin II-induced cytosolic phospholipase A2 activity and growth in vascular smooth muscle cells. Arch Biochem Biophys 402:84-93.
19. 2+ uptake activated by endothelins in rat brain endothelial cells. Eur J Pharmacol 288:1-8.
20. Sugawara F, Ninomiya H, Okamoto Y, Miwa S, Mazda O, Katsura Y, and Masaki T (1996) Endothelìn-1-induced mitogenic responses of Chinese hamster ovary cells expressing human endothelin A: the role of a wortmannin-sensitive signaling pathway. Mol Pharmacol 49:447-457.
21. Trevisi L, Bova S, Cargnelli G, Ceolotto G, and Luciani S (2002) Endothelin-1-induced arachidonic acid release by cytosolic phospholipase A2 activation in rat vascular smooth muscle via extracellular signal-regulated kinases pathway. Biochem Pharmacol 64:425-431.
22. Ui M, Okada T, Hazeki K, and Hazeki O (1995) Wortmannin as a unique probe for an intracellular signalling protein, phosphoinositide 3-kinase. Trends Biochem Sci 20:303-307.
23. 2+-dependent pathway. Am J Physiol 271:C869-C877.
24. Yano H, Nakanishi S, Kimura K, Hanai N, Saitoh Y, Fukui Y, Nonomura Y, and Matsuda Y (1993) Inhibition of histamine secretion by wortmannin through the blockade of phosphatidyl 3-kinase in RBL-2H3 cells, J Biol Chem 268:13-16.