Mechanism of apoptosis induced by squamocin in leukemia cells

Yaoxue Xuebao

Volumn 36, Issue 7, 2001, Pages 501-

  Zhu, Xiao Feng ^a   Xie, Bing Fen ^a   Li, Zhi Ming ^a   Feng, Gong Kan ^a   Zeng, Yi Xin ^a   Liu, Zong Chao ^a  

^a SUN YAT SEN UNIVERSITY   (China)

Author keywords

Apoptosis; HL 60; Squamocin

Indexed keywords

EID: 0042838257     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (12)

1. Oberlies NH, Croy VL, Harrison ML, et al. The annonaceous acetogenin bullatacin is cytotoxic against multidrug-resistant human mamary adenocarcinoma cells [J]. Cancer Lett, 1997,115(1):73-79.
2. Queiroz EF, Roblot F, Duret P, et al. Synthesis, spectroscopy, and cytotoxicity of glycosylated acetogenin derivatives as promising molecules for cancer therapy [J]. J Med Chem, 2000,43(8):1604-1610.
3. Morre DJ, de Caho R, Farley C, et al. Mode of action of bullatacin, a potent antitumor acetogenin: inhibition of NADH oxidase activity of HeLa and HL-60, but not liver, plasma membranes [J]. Life Sci, 1995,56(5):343-348.
4. Miyoshi H, Ohshima M, Shimada H, et al. Essential structural factors of annonaceous acetogenins as potent inhibitors of mitochondrial complex I [J]. Biochem Biophys Acta, 1998,1356(3):443-452.
5. Degli Esposti M, Ghelli A, Ratta M, et al. Natural substances (acetogenins) from the family Annonaceae are powerful inhibitors of mitochondrial NADH dehydrogenase (complex 1) [J]. Biochem J, 1994,301(Pt 1):161-167.
6. Raynaud S, Nemati F, Miccoli L, et al. Antitumoral effects of squamocin on parental and multidrug resistant MCF7 (human breast adenocarcinoma) cell lines [J]. Life Sci, 1999,65(5):525-533.
7. Zhou NN, Zhu XF, Li ZM, et al. Squamocin induced apoptosis in leukemia cell line HL-60 [J]. Chin J Cancer (in Chinese), 2000,19(12):1098-1100.
8. Liu X, Zhou H, Slaughter C, et al. DFF, a heterodimeric protein that function downstream of caspase-3 to trigger DNA fragmentation during apoptosis [J]. Cell, 1997,89(2):175 -184.
9. Nunez G, Benedict MA, Hu Y, et al. Caspases: the protease of the apoptotic pathway [J]. Oncogene, 1998,17 (25):3237-3245.
10. Emoto Y, Manome Y, Meinhardt G, et al. Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells [J]. EMBO J, 1995,14(24):6148-6156.
11. Hirpara JL, Clement MV, Pervaiz S. Intracellular acidification triggered by mitochondrial-derived hydrogen peroxide is an effector mechanism for drug-induced apoptosis in tumor cells [J]. J Biol Chem, 2001,276(1):514-52].
12. Haq R, Zanke B. Inhibition of apoptotic signaling pathways in cancer cells as a mechanism of chemotherapy resistance [J]. Cancer Metastasis Rev, 1998,17(2):233-239.