Pharmacokinetics of recombinant staphylokinase in rats after bolus injection

Fudan University Journal of Medical Sciences

Volumn 29, Issue 4, 2002, Pages 308-310

  Xu, Chang jiang ^a   Liu, Xiao ^a   Li, Duan ^a   Huang, Yang bing ^a   Yu, Ming ^a   Mo, Wei ^a  

^a FUDAN UNIVERSITY   (China)

Author keywords

Bolus injection; Pharmacokinetics; Rats; Recombinant staphylokinase

Indexed keywords

ENZYMES; GENETIC ENGINEERING; MONOCLONAL ANTIBODIES;

RATS;

PHARMACOKINETICS;

MONOCLONAL ANTIBODY; RECOMBINANT STREPTOKINASE; STAPHYLOKINASE; UNCLASSIFIED DRUG;

AREA UNDER THE CURVE; ARTICLE; BOLUS INJECTION; COMPARTMENT MODEL; DOSE RESPONSE; DRUG ACTIVITY; DRUG HALF LIFE; DRUG METABOLISM; INFERIOR CAVA VEIN; NONHUMAN; RAT;

EID: 0042823999     PISSN: 16728467     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Lijnen HR, Stassen JM, Vanlinthout I, et al. Comparative fibrinolytic properties of staphylokinase and streptokinase in animal model of venous thrombosis. Thromb Haemost, 1991,66(4):468
2. Collen D, De Cock F, Vanlinthout I, et al. Comparative thrombolytic and immunogenic properties of staphylokinase and streptokinase. Fibrinolysis, 1992,6:232
3. Lijinen HR, Beelen V, Declerck PJ, et al. Bioimmunoassay for staphylokinase in blood. Thromb Haemost, 1993,70(3);491
4. Collen D, Van de Werf F. Coronary thrombolysis with recombinant staphylokinase in patients with evolving myocardial infarction. Circulation, 1993,87(6):1850
5. Stassen JM, Nystrom A, Hoylaerts M, et al. Antithrombotic effects of thrombolytic agents in a platelet-rich fermral vein thrombosis model in the hamster. Circulation, 1995,91(5):1330