Suppressive effect of Chinese traditional medicine, She-Bi-Tang (Shinpi To) on bronchospasms in aspirin-indtolerant bronchial asthmatic patients - A randomized, group-paralleled comparative trial

Oto-Rhino-Laryngology Tokyo

Volumn 46, Issue SUPPL. 1, 2003, Pages 3-14

  Nishizawa, Yoshio ^a   Nishizawa, Yasuko ^a   Yoshioka, Fumi ^a   Goto, Hiroe Greicy ^a   Fushiki, Shinji ^a  

^a NONE

Author keywords

5 lipoxygenase; Aerosol therapy; Aspirin in tolerant asthma; Eosino phils; Leukotriene; Saiboku to; Shen bi tang; Sodium cromoglicate

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 15 HYDROXYICOSATETRAENOIC ACID; 5 HYDROXYICOSATETRAENOIC ACID; ACETYLSALICYLIC ACID; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; CHINESE DRUG; CROMOGLYCATE DISODIUM; CYCLOOXYGENASE 1; EOSINOPHIL CATIONIC PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 3; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 8; LEUKOTRIENE C4; LEUKOTRIENE D4; LEUKOTRIENE DERIVATIVE; PEPTIDOLEUKOTRIENE; PROSTAGLANDIN D2; PROSTAGLANDIN E2; PROSTAGLANDIN F2 ALPHA; PROSTANOID; SHEN BI TANG; THROMBOCYTE ACTIVATING FACTOR; THROMBOXANE B2; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ARTICLE; ASTHMA; ATTENUATION; BRONCHOSPASM; CHINESE MEDICINE; CHRONIC PAIN; CLINICAL TRIAL; CONCENTRATION RESPONSE; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG EFFICACY; ENZYME ASSAY; FORCED EXPIRATORY VOLUME; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; INHALATION; LUNG LAVAGE; MAJOR CLINICAL STUDY; QUALITY OF LIFE; RADIOIMMUNOASSAY; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY TRACT DISEASE; SYMPTOMATOLOGY; TRADITIONAL MEDICINE;

EID: 0042819952     PISSN: 03869687     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Shoji T, Yoshida S, Sakamoto H, Hasegawa F, Nakagawa H: Anti-inflammatory effect of roxithromycin in patients with aspirin-intolerant asthma. Clin Exp Allergy 29: 950-956, 1994.
2. Nishizawa Y, Nishizawa Y, Yoshioka F, Nosaka S, Amenomori Y, et al: Multicenter, randomized, double-blind trial of roxithromycin to protect asthma attacks in patients with aspirinin-tolerant asthma. Jpn Med J 1: 24-32, 2002.
3. 4 during aspirin-intolerant asthma. Am Rev Respir Dis 119: 48-51, 1992.
4. Nishizawa Y, Nishizawa Y, Yoshioka F, Nosaka S, Amenomori Y, et al: Airway responsiveness to in subjects with aspirin-intolerant asthma. Jpn Med J 3, 2003 (in press).
5. Yamamoto H, Nagata M, Kuramitsu K, Tabe K, Kiuchi H, et al: Inhivition of analgesic-induced asthma by leukotriene receptor antagonist ONO-1078. Am J Respir Crit Care Med 150: 254-257, 1994.
6. Christie PE, Smith CM, Lee TH: The potent and selective sulfidopeptide leukotriene antagonise, SK & F 104353, inhibits aspirin-induced asthma. Am Rev Respir Dis 144: 957-958, 1991.
7. Sladek K, Szczeklik A: Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoke bronchospasm in asthma. Eur Respir J 6: 391-399, 1993.
8. Nasser SMS, Bell GS, Foster S, Spruce KE, MacMillan R, et al: Effect of the 5-lipoxygenase inhibitor ZD2138 on aspirin-induced asthma. Thorax 49: 749-756, 1994.
9. Dahlén B, Margolskee DJ, Zetterstoröm O, Dahlén S: Effect of the leukotriene receptor antagonist MK-0679 on baseline pulmonary function in aspirin sensitive asthmatic subjects. Thorax 48: 1205-1210, 1993.
10. Dahlén B, Nizankowska E, Szczeklik A, Zetterstoröm O, Bochenek C, et al: Benefits from adding the 5-lipoxygenase inhibitor zileuton to conventional therapy in aspirin-intolerant asthmatics. Am J Respir Crit Care Med 157: 1187-1194, 1998.
11. Kobayashi I, Hamasaki Y, Sato R, Zaitu M, Muro E, et al: Saiboku-to, a herbal extract mixture, selectively inhibitory 5-lipoxygenase activity on leukotriene syntheses in rat basophilic leukemia-1 cell. J Ethnophar 48: 32-41, 1994.
12. Hamasaki Y, Kobayashi I, Miyazaki S: Action of Saiko-zai on arachidine acid 5-lipoxygenase enzme. Kampo Immuno-Allergy 8: 30-41, 1994.
13. Nishizawa Y, Nishizawa Y, Fushiki S: The inhibitory effect of Saiboku-to on 5-lipoxygenase activity in human alveolar mast cells. J Trad Med 14: 382-383, 1997.
14. Hirai K, Asada Y, Takaishi T, Nakajima T, Morita Y, et al: Effect of inhalation of Saiboku-to on patients with bronchial asthma. J Trad Med 16 (Suppl 1): 81, 1999.
15. 4 release from human bronchialveolar eosinophil. Jpn Med J 2, 2002 (in press).
16. Nishizawa Y, Nishizawa Y, Fushiki S: Effect of inhalation of Saiboku-to on patients with bronchial asthma. J Trad Med 16 (Suppl 1): 81, 1999.
17. Nishizawa Y, Nishizawa Y, Yoshioka F, Goto GH, Fushiki S: Effect of Choi-po-tang on asthmatic attacks in patients with aspirin-intolerant asthma. J Trad Med 20 (suppl 1), 2003 (in press).
18. Nishizawa Y, Nishizawa Y, Yoshioka F, Nosaka S, Amenomori Y, et al: Suppressive effect of kampo medicine, Choi-po-tang (Japanese name: Saiboku-to, TJ-96) on bronchospsms in aspirin-induced bronchial asthmatic patients and decrease of chronic pain, especially psychological pain. Pain Kampo Med 11: 14-20, 2001.
19. 4) production. Kamp Inmumoallergy 10: 36-42, 1996.
20. Nishizawa Y, Nishizawa Y, Yoshioka F, Amakata Y, Nosaka S, et al: Effect of shen-bi-tang on activity of 5-lipoxy-genase in human alveoral mast cells. Jpn Med J 3, 2002 (in press).
21. Nishizawa Y, Nishizawa Y, Yoshioka F, Amakata Y, Fushiki S: Thyroxine-induced production of superoxide anion by human alveoliar neutrophils and macrophages: a possible mechanism with the development of hyperthyroidism. In vivo 12: 253-258, 1998.
22. Nishizawa Y, Nishii K, Nishizawa Y: Effect of estrogen cell proliferation and increase formation in transformed mouse leydig cells cultured under serumfree condition. Cancer Res 50: 3866-3871, 1990.
23. Nishizawa Y, Amakata Y, Matsushita Y, Nosaka F, Fushiki S: Urinary aracidonic acid cascade in hepatorenal syndrome: evidence for increased vasodilator and decreased vasoconstrictive factor in experimental disease model rat with hepatorenal syndrome. Biotrans Tox Anesth 9: 18, 1988.