Decision tree SAR models for developmental toxicity based on an FDA/TERIS database

SAR and QSAR in Environmental Research

Volumn 14, Issue 2, 2003, Pages 83-96

  Sussman, N B ^a   Arena, V C ^b   Yu, S ^b   Mazumdar, S ^b   Thampatty, B P ^a  

^a UNIVERSITY OF PITTSBURGH   (United States)

^b UNIVERSITY OF PITTSBURGH GRADUATE SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Bagging; Decision tree; Developmental toxicity; FDA TERIS; Model validation; Structure activity relationships

Indexed keywords

BIOACTIVITY; DATABASE SYSTEMS; FORECASTING; RISK ASSESSMENT; TOXICITY;

BAGGING; DEVELOPMENTAL TOXICITY; FOOD AND DRUG ADMINISTRATION; FOOD AND DRUG ADMINISTRATION/TERATOGEN INFORMATION SYSTEM; MODEL ENSEMBLES; MODEL VALIDATION; RELATIONSHIP MODEL; RISKS ASSESSMENTS; STRUCTURE-ACTIVITY RELATIONSHIPS; SYSTEM DATABASE;

DECISION TREES;

ANIMALIA;

TERATOGENIC AGENT;

ARTICLE; CHEMICAL MODEL; COMPUTER PROGRAM; CONGENITAL MALFORMATION; DATA BASE; DECISION TREE; DRUG SURVEILLANCE PROGRAM; ENVIRONMENTAL EXPOSURE; FACTUAL DATABASE; FOOD AND DRUG ADMINISTRATION; HUMAN; PHYSICAL CHEMISTRY; STRUCTURE ACTIVITY RELATION; TOXICITY TESTING; UNITED STATES;

ABNORMALITIES, DRUG-INDUCED; CHEMISTRY, PHYSICAL; DATABASES; DATABASES, FACTUAL; DECISION TREES; ENVIRONMENTAL EXPOSURE; HUMANS; MODELS, CHEMICAL; NO-OBSERVED-ADVERSE-EFFECT LEVEL; SOFTWARE; STRUCTURE-ACTIVITY RELATIONSHIP; TERATOGENS; TOXICITY TESTS; UNITED STATES; UNITED STATES FOOD AND DRUG ADMINISTRATION;

EID: 0042768071     PISSN: 1062936X     EISSN: None     Source Type: Journal    
DOI: 10.1080/1062936031000073126     Document Type: Article

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