(-)-Sparteine-Mediated Directed ortho-Metalation of N-Cumyl-N- ethylferrocenecarboxamide. Versatile Routes to Functionalized Planar Chiral Ferrocenecarboxamides, Amines, Esters and Phosphines

Advanced Synthesis and Catalysis

Volumn 345, Issue 3, 2003, Pages 370-382

  Metallinos, Costa ^a   Szillat, Hauke ^a   Taylor, Nicholas J ^b   Snieckus, Victor ^a  

^a QUEEN S UNIVERSITY   (Canada)

^b UNIVERSITY OF WATERLOO   (Canada)

Author keywords

Cumyl; Enantioselective; Heck reaction; Metalation; Planar chiral ferrocene, ring closing metathesis

Indexed keywords

1 ETHYL 3,4 (1,2 FERROCENYL) 5 METHYLENE 2 PIPERIDINONE; 2 [(N ETHYL N METHYLAMINO)METHYL] 1 IODOFERROCENE; 2 DIPHENYLPHOSPHINO N ETHYLFERROCENECARBOXIDE; 2 HYDROXYMETHYL N CUMYL N ETHYLFERROCENECARBOXAMIDE; 2 IODO N CUMYL N ETHYLFERROCENECARBOXAMIDE; 2 IODO N ETHYLFERROCENECARBOXAMIDE; 2 METHOXYMETHYL N CUMYL N ETHYLFERROCENECARBOXAMIDE; 2 METHOXYMETHYL N ETHYLFERROCENECARBOXAMIDE; 2 METHYL N CUMYL N ETHYLFERROCENECARBOXAMIDE; 2 METHYL N ETHYLFERROCENECARBOXAMIDE; 2 THIOMETHYL N CUMYL N ETHYLFERROCENECARBOXAMIDE; 2 THIOMETHYL N ETHYLFERROCENECARBOXAMIDE; 2 TRIFLUOROETHOXYMETHYL N ETHYLFERROCENECARBOXAMIDE; 2 TRIMETHYLSILYL N CUMYL N ETHYLFERROCENECARBOXAMIDE; 2 TRIMETHYLSILYL N ETHYLFERROCENECARBOXAMIDE; AMINE; ESTER; FERROCENE DERIVATIVE; N CUMYL N ETHYLFERROCENECARBOXAMIDE; PHOSPHINE DERIVATIVE; SPARTEINE; UNCLASSIFIED DRUG;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL MODIFICATION; CHIRALITY; COLUMN CHROMATOGRAPHY; ENANTIOSELECTIVITY; HECK REACTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; INFRARED SPECTROSCOPY; METALATION; PROTON NUCLEAR MAGNETIC RESONANCE; RING CLOSING METATHESIS;

EID: 0042751428     PISSN: 16154150     EISSN: None     Source Type: Journal    
DOI: 10.1002/adsc.200390042     Document Type: Article

References (50)

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