메뉴 건너뛰기




Volumn 24, Issue 8, 2003, Pages 778-782

Hepatotoxicity and toxicokinetics of ketoconazole in rabbits

Author keywords

Hepatotoxicity; Ketoconazole; Pharmacokinetics

Indexed keywords

ALANINE AMINOTRANSFERASE; ANTIFUNGAL AGENT; ASPARTATE AMINOTRANSFERASE; DIAZEPAM; KETOCONAZOLE;

EID: 0042735038     PISSN: 16714083     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (14)

References (18)
  • 2
    • 0028194936 scopus 로고
    • Fatal acute hepatic necrosis due to fluconazole
    • Jacobson MA, Hanks DK, Ferrell LD. Fatal acute hepatic necrosis due to fluconazole. Am J Med 1994; 96: 188-90.
    • (1994) Am J Med , vol.96 , pp. 188-190
    • Jacobson, M.A.1    Hanks, D.K.2    Ferrell, L.D.3
  • 5
    • 0041569096 scopus 로고    scopus 로고
    • Acute hepatic failure-induced death due to ketoconazole
    • Fu HG, Zhang T. Acute hepatic failure-induced death due to ketoconazole. Adverse Drug Reactions J 2001; 3: 159.
    • (2001) Adverse Drug Reactions J , vol.3 , pp. 159
    • Fu, H.G.1    Zhang, T.2
  • 6
    • 0042571273 scopus 로고
    • Ketoconazole and hepatotoxic damage
    • Deng PY. Ketoconazole and hepatotoxic damage. Chin Pharm Affair 1995; 9: 49-51.
    • (1995) Chin Pharm Affair , vol.9 , pp. 49-51
    • Deng, P.Y.1
  • 8
    • 0023158144 scopus 로고
    • Hepatic reactions associated with ketoconazole in the United Kingdom
    • Lake-Bakaar G, Scheuer PJ, Sherlock S. Hepatic reactions associated with ketoconazole in the United Kingdom. Br Med J 1987; 294: 419-22.
    • (1987) Br Med J , vol.294 , pp. 419-422
    • Lake-Bakaar, G.1    Scheuer, P.J.2    Sherlock, S.3
  • 9
    • 0025690211 scopus 로고
    • Deacetylated ketoconazole: A major ketoconazole metabolite isolated from mouse liver
    • Whitehouse LW, Menzies A, Dawson B, Zamecnik J, Sy WW. Deacetylated ketoconazole: a major ketoconazole metabolite isolated from mouse liver. J Pharm Biomed Anal 1990; 8: 603-6.
    • (1990) J Pharm Biomed Anal , vol.8 , pp. 603-606
    • Whitehouse, L.W.1    Menzies, A.2    Dawson, B.3    Zamecnik, J.4    Sy, W.W.5
  • 10
    • 0343416836 scopus 로고    scopus 로고
    • Metabolism of ketoconazole and deacetylated ketoconazole by rat hepatic microsomes and flavin-containing monooxygenases
    • Rodriguez RJ, Acosta D Jr. Metabolism of ketoconazole and deacetylated ketoconazole by rat hepatic microsomes and flavin-containing monooxygenases. Drug Metab Dispos 1997; 25: 772-7.
    • (1997) Drug Metab Dispos , vol.25 , pp. 772-777
    • Rodriguez, R.J.1    Acosta D., Jr.2
  • 11
    • 0031588765 scopus 로고    scopus 로고
    • N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes
    • Rodriguez RJ, Acosta D. N-deacetyl ketoconazole-induced hepatotoxicity in a primary culture system of rat hepatocytes. Toxicology 1997; 117: 123-31.
    • (1997) Toxicology , vol.117 , pp. 123-131
    • Rodriguez, R.J.1    Acosta, D.2
  • 12
    • 0033836020 scopus 로고    scopus 로고
    • Isoform specificity of N-deacetyl ketoconazole by human and rabbit flavin-containing monooxygenases
    • Rodriguez RJ, Miranda CL. Isoform specificity of N-deacetyl ketoconazole by human and rabbit flavin-containing monooxygenases. Drug Metab Dispos 2000; 28: 1083-6.
    • (2000) Drug Metab Dispos , vol.28 , pp. 1083-1086
    • Rodriguez, R.J.1    Miranda, C.L.2
  • 13
    • 0042571272 scopus 로고    scopus 로고
    • Design of pharmacological experiment and statistic analysis
    • Xu SY, Bian RL, Chen X. Beijing: People's Medical Publishing House
    • Sun RY, Ma YM, Hong ZY. Design of pharmacological experiment and statistic analysis. In: Xu SY, Bian RL, Chen X. Methodology of pharmacological experiment. 3rd ed. Beijing: People's Medical Publishing House; p195-223.
    • Methodology of Pharmacological Experiment. 3rd Ed. , pp. 195-223
    • Sun, R.Y.1    Ma, Y.M.2    Hong, Z.Y.3
  • 15
    • 0025950745 scopus 로고
    • Hormonal regulation of microsomal flavin-containing monooxygenase: Tissue-dependent expression and substrate specificity
    • Lemoine A, Williams DE, Cresteil T, Leroux JP. Hormonal regulation of microsomal flavin-containing monooxygenase: tissue-dependent expression and substrate specificity. Mol Pharmacol 1991; 40: 211-7.
    • (1991) Mol Pharmacol , vol.40 , pp. 211-217
    • Lemoine, A.1    Williams, D.E.2    Cresteil, T.3    Leroux, J.P.4
  • 16
    • 0031878122 scopus 로고    scopus 로고
    • Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3, and 5
    • Cherrington NJ, Cao Y, Cherrington JW, Rose RL, Hodgson E. Physiological factors affecting protein expression of flavin-containing monooxygenases 1, 3, and 5. Xenobiotica 1998; 28: 673-82.
    • (1998) Xenobiotica , vol.28 , pp. 673-682
    • Cherrington, N.J.1    Cao, Y.2    Cherrington, J.W.3    Rose, R.L.4    Hodgson, E.5
  • 17
    • 0023680420 scopus 로고
    • Dose and sex-dependent disposition of ketoconazole in rats
    • Sjoberg P, Ekman L, Lundqvist T. Dose and sex-dependent disposition of ketoconazole in rats. Arch Toxicol 1988; 62: 177-80.
    • (1988) Arch Toxicol , vol.62 , pp. 177-180
    • Sjoberg, P.1    Ekman, L.2    Lundqvist, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.