Current concepts and novel applications of LH activity in ovarian stimulation

Trends in Endocrinology and Metabolism

Volumn 14, Issue 6, 2003, Pages 267-273

  Filicori, Marco ^a   Cognigni, Graciela E ^a   Pocognoli, Patrizia ^a   Ciampaglia, Walter ^a   Bernardi, Silvia ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

FOLLITROPIN; GONADOTROPIN; LUTEINIZING HORMONE;

ANOVULATION; GRANULOSA CELL; HORMONAL REGULATION; HORMONE ACTION; HUMAN; LUTEINIZATION; MENSTRUAL CYCLE; OVARY FOLLICLE; OVARY FOLLICLE DEVELOPMENT; OVULATION; OVULATION INDUCTION; PRIORITY JOURNAL; REPRODUCTION; REVIEW; THECA CELL;

EID: 0042734524     PISSN: 10432760     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1043-2760(03)00085-7     Document Type: Review

References (73)

1. Dorrington, J.H. and Armstrong, D.T. (1979) Effects of FSH on gonadal functions. Recent Prog. Horm. Res. 35, 301-342
2. Shima, K. et al. (1987) Gonadotropin binding sites in human ovarian follicles and corpora lutea during the menstrual cycle. Obstet. Gynecol. 69, 800-806
3. Zeleznik, A.J. and Hillier, S.G. (1984) The role of gonadotropins in the selection of the preovulatory follicle. Clin. Obstet. Gynecol. 27, 927-940
4. Hillier, S.G. et al. (1994) Follicular oestrogen synthesis: the two-cell, two-gonadotrophin' model revisited. Mol. Cell. Endocrinol. 100, 51-54
5. Sullivan, M.W. et al. (1999) Ovarian responses in women to recombinant follicle-stimulating hormone and luteinizing hormone (LH): a role for LH in the final stages of follicular maturation. J. Clin. Endocrinol. Metab. 84, 228-232
6. Filicori, M. et al. (2002) Stimulation and growth of antral ovarian follicles by selective LH activity administration in women. J. Clin. Endocrinol. Metab. 87, 1156-1161
7. Filicori, M. et al. (2002) Intracytoplasmic sperm injection pregnancy after low-dose human chorionic gonadotropin alone to support ovarian folliculogenesis. Fertil. Steril. 78, 414-416
8. Campbell, B.K. et al. (1999) Examination of the relative role of FSH and LH in the mechanism of ovulatory follicle selection in sheep. J. Reprod. Fertil. 117, 355-367
9. The European and Israeli Study Group on Highly Purified Menotropin versus Recombinant Follicle-Stimulating Hormone, (2002) Efficacy and safety of highly purified menotropin versus recombinant follicle-stimulating hormone in in vitro fertilization/intracytoplasmic sperm injection cycles: a randomized, comparative trial. Fertil. Steril. 78, 520-528
10. Rodgers, M. et al. (1992) Human chorionic gonadotrophin contributes to the bioactivity of Pergonal. Clin. Endocrinol. (Oxf.) 37, 558-564
11. Stokman, P.G. et al. (1993) Human chorionic gonadotropin in commercial human menopausal gonadotropin preparations. Fertil. Steril. 60, 175-178
12. Couzinet, B. et al. (1988) Stimulation of ovarian follicular maturation with pure follicle-stimulating hormone in women with gonadotropin deficiency. J. Clin. Endocrinol. Metab. 66, 552-556
13. Shoham, Z. et al. (1991) Results of ovulation induction using human menopausal gonadotropin or purified follicle-stimulating hormone in hypogonadotropic hypogonadism patients. Fertil. Steril. 56, 1048-1053
14. Schoot, D.C. et al. (1992) Human recombinant follicle-stimulating hormone induces growth of preovulatory follicles without concomitant increase in androgen and estrogen biosynthesis in a woman with isolated gonadotropin deficiency. J. Clin. Endocrinol. Metab. 74, 1471-1473
15. Schoot, D.C. et al. (1994) Recombinant human follicle-stimulating hormone and ovarian response in gonadotrophin-deficient women. Hum. Reprod. 9, 1237-1242
16. Balasch, J. et al. (1995) The role of luteinizing hormone in human follicle development and oocyte fertility: evidence from in-vitro fertilization in a woman with long-standing hypogonadotrophic hypogonadism and using recombinant human follicle stimulating hormone. Hum. Reprod. 10, 1678-1683
17. The European Recombinant Human LH Study Group, (1998) Recombinant human luteinizing hormone (LH) to support recombinant human follicle-stimulating hormone (FSH)-induced follicular development in LH- and FSH-deficient anovulatory women: a dose-finding study. J. Clin. Endocrinol. Metab. 83, 1507-1514
18. Filicori, M. et al. (1999) Low-dose human chorionic gonadotropin therapy can improve sensitivity to exogenous follicle-stimulating hormone in patients with secondary amenorrhea. Fertil. Steril. 72, 1118-1120
19. Doody, K.M. et al. (2002) Daily low dose recombinant hCG and low dose recombinant FSH: a novel treatment for hypogonadotropic hypogonadism. Fertil. Steril. 76, S105
20. Shoham, Z. et al. (1993) Luteinizing hormone: its role, mechanism of action, and detrimental effects when hypersecreted during the follicular phase. Fertil. Steril. 59, 1153-1161
21. Ludwig, M. et al. (1999) Oocyte quality and treatment outcome in intracytoplasmic sperm injection cycles of polycystic ovarian syndrome patients. Hum. Reprod. 14, 354-358
22. Nestler, J.E. et al. (2002) Strategies for the use of insulin-sensitizing drugs to treat infertility in women with polycystic ovary syndrome. Fertil. Steril. 77, 209-215
23. Nestler, J.E. et al. (1998) Effects of Metformin on spontaneous and Clomiphene-induced ovulation in the polycystic ovary syndrome. N. Engl. J. Med. 338, 1876-1880
24. la Marca, A. et al. (2002) Insulin-lowering treatment reduces aromatase activity in response to follicle-stimulating hormone in women with polycystic ovary syndrome. Fertil. Steril. 78, 1234-1239
25. Glueck, C.J. et al. (2002) Pregnancy outcomes among women with polycystic ovary syndrome treated with metformin. Hum. Reprod. 17, 2858-2864
26. Jakubowicz, D.J. et al. (2002) Effects of metformin on early pregnancy loss in the polycystic ovary syndrome. J. Clin. Endocrinol. Metab. 87, 524-529
27. Costello, M.F. and Eden, J.A. (2003) A systematic review of the reproductive system effects of metformin in patients with polycystic ovary syndrome. Fertil. Steril. 79, 1-13
28. Venturoli, S. et al. (1987) Induction of ovulation in polycystic ovary: human menopausal gonadotropin or human urinary follicle stimulating hormone? Int. J. Fertil. 32, 66-70
29. Venturoli, S. et al. (1984) Comparison between human urinary follicle-stimulating hormone and human menopausal gonadotropin treatment in polycystic ovary. Obstet. Gynecol. 63, 6-11
30. Larsen, T. et al. (1990) Comparison of urinary human follicle-stimulating hormone and human menopausal gonadotropin for ovarian stimulation in polycystic ovarian syndrome. Fertil. Steril. 53, 426-431
31. Sagle, M.A. et al. (1991) A comparative, randomized study of low-dose human menopausal gonadotropin and follicle-stimulating hormone in women with polycystic ovarian syndrome. Fertil. Steril. 55, 56-60
32. Nugent, D. et al. (2000) Gonadotrophin therapy for ovulation induction in subfertility associated with polycystic ovary syndrome. Cochrane Database Syst. Rev. CD000410
33. Hughes, E. et al. (2000) Ovulation induction with urinary follicle stimulating hormone versus human menopausal gonadotropin for clomiphene-resistant polycystic ovary syndrome. Cochrane Database Syst. Rev. CD000087
34. Daya, S. et al. (1995) Follicle-stimulating hormone versus human menopausal gonadotropin for in vitro fertilization cycles: a meta-analysis. Fertil. Steril. 64, 347-354
35. Al Inany, H. et al. (2003) Meta-analysis of recombinant versus urinary-derived FSH: an update. Hum. Reprod. 18, 305-313
36. Agrawal, R. et al. (2000) Follicle-stimulating hormone or human menopausal gonadotropin for ovarian stimulation in in vitro fertilization cycles: a meta-analysis. Fertil. Steril. 73, 338-343
37. Shoham, Z. (2002) The clinical therapeutic window for luteinizing hormone in controlled ovarian stimulation. Fertil. Steril. 77, 1170-1177
38. Westergaard, L.G. et al. (2000) Increased risk of early pregnancy loss by profound suppression of luteinizing hormone during ovarian stimulation in normogonadotrophic women undergoing assisted reproduction. Hum. Reprod. 15, 1003-1008
39. Westergaard, L.G. et al. (2001) Human menopausal gonadotropin versus recombinant follicle-stimulating hormone in normogonadotropic women down-regulated with a gonadotropin-releasing hormone agonist who were undergoing in vitro fertilization and intracytoplasmic sperm injection: a prospective randomized study. Fertil. Steril. 76, 543-549
40. Humaidan, P. et al. (2002) Ovarian response and pregnancy outcome related to mid-follicular LH levels in women undergoing assisted reproduction with GnRH agonist down-regulation and recombinant FSH stimulation. Hum. Reprod. 17, 2016-2021
41. Sills, E.S. et al. (1999) A prospective, randomized comparison of ovulation induction using highly purified follicle-stimulating hormone alone and with recombinant human luteinizing hormone in in-vitro fertilization. Hum. Reprod. 14, 2230-2235
42. Balasch, J. et al. (2001) The effect of exogenous luteinizing hormone (LH) on oocyte viability: evidence from a comparative study using recombinant human follicle-stimulating hormone (FSH) alone or in combination with recombinant LH for ovarian stimulation in pituitary-suppressed women undergoing assisted reproduction. J. Assist. Reprod. Genet. 18, 250-256
43. Tesarik, J. and Mendoza, C. (2002) Effects of exogenous LH administration during ovarian stimulation of pituitary down-regulated young oocyte donors on oocyte yield and developmental competence. Hum. Reprod. 17, 3129-3137
44. Ng, E.H. et al. (2001) HMG is as good as recombinant human FSH in terms of oocyte and embryo quality: a prospective randomized trial. Hum. Reprod. 16, 319-325
45. Gordon, U.D. et al. (2001) A randomized prospective assessor-blind evaluation of luteinizing hormone dosage and in vitro fertilization outcome. Fertil. Steril. 75, 324-331
46. Schoolcraft, W.B. et al. (1999) Blastocyst culture and transfer: analysis of results and parameters affecting outcome in two in vitro fertilization programs. Fertil. Steril. 72, 604-609
47. Kilani, Z. et al. A prospective, randomised, controlled trial comparing HP HMG to recombinant FSH in women undergoing ICSI: ovarian response and clinical outcomes. Hum. Reprod. (in press)
48. Filicori, M. (2003) Use of luteinizing hormone in the treatment of infertility: time for reassessment? Fertil. Steril. 79, 253-255
49. Mercan, R. et al. (1997) Improved oocyte quality is obtained with follicle stimulating hormone alone than with follicle stimulating hormone/human menopausal gonadotrophin combination. Hum. Reprod. 12, 1886-1889
50. Imthurn, B. et al. (1996) Nuclear maturity and oocyte morphology after stimulation with highly purified follicle stimulating hormone compared to human menopausal gonadotrophin. Hum. Reprod. 11, 2387-2391
51. Weissman, A. et al. (1999) Intracytoplasmic sperm injection after follicle stimulation with highly purified human follicle-stimulating hormone compared with human menopausal gonadotropin. J. Assist. Reprod. Genet. 16, 63-68
52. Agrawal, R. et al. (1998) Implications of using follicle-stimulating hormone preparations depleted of luteinizing hormone to achieve follicular growth in in vitro fertilization. Gynecol. Endocrinol. 12, 9-15
53. Mendoza, C. et al. (1999) Relationship between fertilization results after intracytoplasmic sperm injection, and intrafollicular steroid, pituitary hormone and cytokine concentrations. Hum. Reprod. 14, 628-635
54. Mendoza, C. et al. (2002) Follicular fluid markers of oocyte developmental potential. Hum. Reprod. 17, 1017-1022
55. Tanbo, T. et al. (1990) Stimulation with human menopausal gonadotropin versus follicle-stimulating hormone after pituitary suppression in polycystic ovarian syndrome. Fertil. Steril. 53, 798-803
56. Teissier, M.P. et al. (1999) Recombinant human follicle stimulating hormone versus human menopausal gonadotrophin induction: effects in mature follicle endocrinology. Hum. Reprod. 14, 2236-2241
57. Fanchin, R. et al. (1993) Premature elevation of plasma progesterone alters pregnancy rates of in vitro fertilization and embryo transfer. Fertil. Steril. 59, 1090-1094
58. Silverberg, K.M. et al. (1991) Serum progesterone levels predict success of in vitro fertilization/embryo transfer in patients stimulated with leuprolide acetate and human menopausal gonadotropins. J. Clin. Endocrinol. Metab. 73, 797-803
59. Copperman, A.B. et al. (1995) Relationship between circulating human chorionic gonadotropin levels and premature luteinization in cycles of controlled ovarian hyperstimulation. Fertil. Steril. 63, 1267-1271
60. Chetkowski, R.J. et al. (1997) In premature luteinization, progesterone induces secretory transformation of the endometrium without impairment of embryo viability. Fertil. Steril. 68, 292-297
61. Hofmann, G.E. et al. (1993) Premature luteinization in controlled ovarian hyperstimulation has no adverse effect on oocyte and embryo quality. Fertil. Steril. 60, 675-679
62. Legro, R.S. et al. (1993) Premature luteinization as detected by elevated serum progesterone is associated with a higher pregnancy rate in donor oocyte in-vitro fertilization. Hum. Reprod. 8, 1506-1511
63. Ubaldi, F. et al. (1996) Premature luteinization in in vitro fertilization cycles using gonadotropin-releasing hormone agonist (GnRH-a) and recombinant follicle-stimulating hormone (FSH) and GnRH-a and urinary FSH. Fertil. Steril. 66, 275-280
64. Shulman, A. et al. (1996) The significance of an early (premature) rise of plasma progesterone in in vitro fertilization cycles induced by a "long protocol" of gonadotropin releasing hormone analogue and human menopausal gonadotropins. J. Assist. Reprod. Genet. 13, 207-211
65. Hofmann, G.E. et al. (1993) Premature luteinization is not eliminated by pituitary desensitization with leuprolide acetate in women undergoing gonadotrophin stimulation who demonstrated premature luteinization in a prior gonadotrophin-only cycle. Hum. Reprod. 8, 695-698
66. Ubaldi, F. et al. (1996) Subtle progesterone rise after the administration of the gonadotrophin-releasing hormone antagonist cetrorelix in intracytoplasmic sperm injection cycles. Hum. Reprod. 11, 1405-1407
67. Filicori, M. et al. (2001) Luteinizing hormone activity in menotropins optimizes folliculogenesis and treatment in controlled ovarian stimulation. J. Clin. Endocrinol. Metab. 86, 337-343
68. Filicori, M. et al. (1999) Luteinizing hormone activity supplementation enhances follicle-stimulating hormone efficacy and improves ovulation induction outcome. J. Clin. Endocrinol. Metab. 84, 2659-2663
69. Filicori, M. et al. (2002) Modulation of folliculogenesis and steroidogenesis in women by graded menotrophin administration. Hum. Reprod. 17, 2009-2015
70. Filicori, M. et al. Comparison of controlled ovarian stimulation with human menopausal gonadotropin and recombinant follicle stimulating hormone. Fertil. Steril. (in press)
71. Strehler, E. et al. (2001) Impact of recombinant follicle-stimulating hormone and human menopausal gonadotropins on in vitro fertilization outcome. Fertil. Steril. 75, 332-336
72. Martin, L. et al. (2002) Daily low dose recombinant hCG and recombinant FSH: a novel stimulation protocol for IVF. Fertil. Steril. 76, S19
73. Filicori, M. and Cognigni, G.E. (2001) Clinical review 126: roles and novel regimens of luteinizing hormone and follicle-stimulating hormone in ovulation induction. J. Clin. Endocrinol. Metab. 86, 1437-1441