Synthesis and anti-HIV activity of (±)-calanolide A and its analogues

Yaoxue Xuebao

Volumn 34, Issue 9, 1999, Pages 673-678

  Zhou, Chunmei ^a   Wang, Lin ^a   Zhang, Minglong ^a   Zhao, Zhizhong ^a   Zhang, Xingquan ^b   Chen, Xianghong ^b   Chen, Hongshan ^b  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b INSTITUTE OF MEDICINAL BIOTECHNOLOGY   (China)

Author keywords

( ) 11 demethyl and 6,6,11 demethyl calanolide A and B; ( ) calanolide A; Anti HIV activity

Indexed keywords

EID: 0042715154     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Kashman Y, Gustafson KR, Fuller RW, et al. The calanolides, a novel HIV-inhibitory class of coumarin derivatives from the tropical rainforest tree, Calophyllum lanigerum. J Med Chem, 1992,35:2735
2. Chenera B, West ML, Finkelstein JA, et al. Total synthesis of (±)-calanolide A, a non-nucleoside inhibitor of HIV-1 reverse transcriptase. J Org Chem, 1993,58:5605
3. Kucherenko A, Flavin MT, Boulanger WA, et al. Novel approach for synthesis of (±)-calanolide A and its anti-HIV activity. Tetrahedron Lett, 1995,36:5475
4. Deshpande PP, Tagliaferri F, Victory SF, et al. Synthesis of optically active calanolides A and B. J Org Chem, 1995, 60:2964
5. Flavin MT, Rizzo JD, Khilevich A, et al. Synthesis, chromatographic resolution, and anti-human immunodeficiency virus activity of (±)-calanolide A and its enantiomers. J Med Chem, 1996,39:1303
6. Vanallan JA, Acrolein acetal. In: Rabjohn N ed. Organic Syntheses. New York: John Wiley and Sons, 1963,4:21-22