Sex-sensitive cognitive performance in untreated patients with early onset gender identity disorder

Psychoneuroendocrinology

Volumn 28, Issue 7, 2003, Pages 906-915

  Haraldsen, I R ^a   Opjordsmoen, S ^a   Egeland, T ^a   Finset, A ^a  

^a UNIVERSITY OF OSLO   (Norway)

Author keywords

Cognitive ability; Cognitive pattern; Gender identity; Neuropsychological testing; Sex sensitive differences

Indexed keywords

SEX HORMONE;

ACUTE DISEASE; ADULT; AGE; ANALYSIS OF VARIANCE; ARITHMETIC; ARTICLE; COGNITION; CONTROLLED STUDY; EDUCATION; FEMALE; GENDER IDENTITY DISORDER; HORMONAL THERAPY; HUMAN; LOGIC; MAJOR CLINICAL STUDY; MALE; NORWAY; PERCEPTION; PREDICTION; PRIORITY JOURNAL; ROTATION; SAMPLE; SEX ROLE; TASK PERFORMANCE; UNITED STATES; VERBALIZATION; VISION TEST;

EID: 0042700100     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-4530(02)00107-5     Document Type: Article

References (40)

1. Altman D. Practical Statistics for Medical Research. 1991;Chapman, & Hall, London.
2. APA, 1994. Diagnostic and Statistical Manual of Mental Disorders. American Psychiatric Association, Washington, DC.
3. Breedlove S. Sex on the brain. Nature. 389:1997;801.
4. Christiansen K., Knussmann R. Sex hormones and cognitive functioning in men. Neuropsychobiology. 18:1987;27-36.
5. Cohen-Kettenis P.T., van Goozen S.H., Doorn C.D., Gooren L.J. Cognitive ability and cerebral lateralisation in transsexuals. Psychoneuroendocrinology. 23:1998;631-641.
6. Dohler K.D., Srivastava S.S., Shryne J.E., Jarzab B., Sipos A., Gorski R.A. Differentiation of the sexually dimorphic nucleus in the preoptic area of the rat brain is inhibited by postnatal treatment with an estrogen antagonist. Neuroendocrinology. 38:1984;297-301.
7. Ekstrøm R., French J., Harman H., Dermen D. Manual for Kit Factor Referenced Cognitive Test. 1976;Education Testing Service, Princton, NJ.
8. Foucault M. Histoire de la sexualité 1976;Bibliothèque des histoires, Paris.
9. Geschwind N., Galaburda A.M. Cerebral lateralization. Biological mechanisms, associations, and pathology: I. A hypothesis and a program for research. Arch. Neurol. 42:1985;428-459.
10. Gouchie C., Kimura D. The relationship between testosterone levels and cognitive ability patterns. Psychoneuroendocrinology. 16:1990;323-334.
11. Halpern D.F. Sex Differences in Cognitive Abilities. 2000;Lawrence Erlbaum Associates, Mahwah, NJ.
12. Hampson E., Kimura D. Reciprocal effects of hormonal fluctuations on human motor and perceptual spatial skills. Behav. Neurosci. 3:1988;456-459.
13. Hampson E., Rovet J.F., Altmann D. Spatial reasoning in children with congenital adrenal hyperplasia due to 21-hydroxylase deficiency. Dev. Neuropsychol. 14:1998;299-320.
14. James T.W., Kimura D. Sex differences in remembering the location objects in an array: location-shifts versus location-exchanges. Evol. Hum. Behav. 18:1997;155-163.
15. Janowsky J.S., Chavez B., Zamboni B.D., Orwoll E. The cognitive neuropsychology of sex hormones in men and women. Dev. Neuropsychol. 14:1998;421-440.
16. Kelso W.M., Nicholls M.E.R., Warne G.L. Effects of prenatal androgen exposure on cerebral lateralization in patients with congenital adrenal hyperplasia (CAH). Brain Cogn. 40:1999;153-156.
17. Kimura D. Sex differences in the brain. Sci. Am. 267:1992;81-87.
18. Kramer J.H., Delis D.C., Kaplan E., O'Donnell L., Prifitera A. Developmental sex differences in verbal learning. Neuropsychology. 11:1997;577-584.
19. Kruijver F.P., Zhou J.N., Pool C.W., Hofman M.A., Gooren L.J., Swaab D.F. Male-to-female transsexuals have female neuron numbers in a limbic nucleus. J. Clin. Endocrinol. Metab. 85:2000;2034-2041.
20. Lamielle, R.J., 1995. Age, sex, education, and verbal intelligence stratification of the rey auditory verbal learning test in an outpatient clinical population. Dissertation Abstracts International: Section B: The Sciences and Engineering, pp. 3633.
21. LeVay S., Hamer D.H. Evidence for a biological influence in male homosexuality. Sci. Am. 270:1994;44-49.
22. Levine, S.B., Brown, G., Coleman, E., Cohen Kettenis, P., Hage, J.J., Van Maasdam, J., Petersen, M., Pfaefflin, F., Schaefer, L.C., 1998. Harry Benjamin International Gender Dysphoria Association's the standards of care for gender identity disorders. Int. J. Transgender 2, Np.
23. Linn M.C., Petersen A.C. Emergence and characterization of sex differences in spatial ability: a meta-analysis. Child Dev. 56:1985;1479-1498.
24. Lothstein L. Sex reassignment sugery. Am. J. Psychiat. 139:1982;417-426.
25. McEwen B.S. Hormones as regulators of brain development: life-long effects related to health and disease. Acta Paediatr.Suppl. 422:1997;41-44.
26. McKeever W.F. Hormone and hemisphericity hypotheses regarding cognitive sex differences: possible future explanatory power, but current empirical chaos. Learn. Indiv. Diff. 7:1995;323-340.
27. Meguro Y., Fujii T., Yamadori A., Tsukiura T., Suzuki K., Okuda J., Osaka M. The nature of age-related decline on the reading span task. J. Clin. Exp. Neuropsychol. 22:2000;391-398.
28. Miles C., Green R., Sanders G., Hines M. Estrogen and memory in a transsexual population. Horm. Behav. 34:1998;199-208.
29. Resnick S.M., Berenbaum S.A., Gottesman I.I., Bouchard T.J. Early hormonal influences on cognitive functioning in congenital adrenal hyperplasia. Dev. Psychol. 22:1986;191-198.
30. Sherwin B. Estrogenic effects on memory in women. Ann. N.Y. Acad. Sci. 743:1994;213-230.
31. Silverman I., Phillips K. Effects of estrogen changes over the menstrual cycle on spatial performance. Ethol. Sociobiol. 14:1993;250-270.
32. Slabbekoorn D., van Goozen S.H., Megens J., Gooren L.J., Cohen-Kettenis P.T. Activating effects of cross-sex hormones on cognitive functioning: a study of short-term and long-term hormone effects in transsexuals. Psychoneuroendocrinology. 24:1999;423-447.
33. SPSS, 2001. Statistical Package for the Social Sciences. 11.0. SPSS, Chicago, IL.
34. Statistics, 2002. Survey of Living Conditions 1996-1998. Statistics of Norway, http://www.ssb.no .
35. Swaab D.F., Gooren L.J.G., Hofman M.A. Brain research, gender and sexual orientation. J. Homosex. New York. 28:1995;283-301.
36. van Goozen S., Cohen-Kettenis P.T., Gooren L.J.G., Frijda N., van de Poll N. Activating effects of androgens on cognitive performance: causal evidence in a group of female to male transsexuals. Neuropsychologia. 10:1994;1153-1157.
37. Voyer D., Voyer S., Bryden M. Magnitude of sex differences in spatial abilities: a meta-analysis and consideration of critical variables. Psychol.Bull. 117:1995;250-270.
38. Williams C., Meck W. The organizational effects of gonadal steroids on sexual dimorphic spatial ability. Psychoneuroendocrinology. 16:1990;155-176.
39. Wålinder J., Luft R., Hult B., Sundberg D. Transsexualism. Lækartidn. 74:1977;3857-3860.
40. Zhou J.N., Hofman M.A., Gooren L., Swaab D.F. A sex difference in the human brain and its relation to transsexuality. Nature. 378:1995;63-69.