Pediatric drug formulations of sodium benzoate: I. Coated granules with a hydrophilic binder

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 56, Issue 2, 2003, Pages 247-253

  Breitkreutz, Jörg ^a   Bornhöft, Martin ^b   Wöll, Florian ^b   Kleinebudde, Peter ^c  

^a UNIVERSITY OF MÜNSTER   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

^c HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Extrusion; Inherited metabolic disorders; Microencapsulation; Orphan drugs; Pediatric formulations; Polymethacrylate; Roller compacting; Sodium benzoate; Solvent free granulation; Urea cycle disorders

Indexed keywords

ALCOHOL; BENZOIC ACID; CITRIC ACID TRIETHYL ESTER; EUDRAGIT; MACROGOL 200; MACROGOL 4000; MACROGOL DERIVATIVE; METHACRYLIC ACID DERIVATIVE; POLYMER; POLYMETHACRYLIC ACID; SILICON DIOXIDE; SYLOID;

ARTICLE; CHILD HEALTH CARE; COMPRESSION; DRUG FORMULATION; DRUG GRANULATION; DRUG INDICATION; DRUG MEGADOSE; DRUG SOLUBILITY; DRUG STABILITY; FILM COATING; HYDROPHILICITY; MICROCAPSULE; MICROENCAPSULATION; PELLET EXTRUSION; PHARMACEUTICAL ENGINEERING;

EID: 0042641469     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0939-6411(03)00091-2     Document Type: Article

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