Granulomatous blepharitis successfully treated with tranilast [18]

British Journal of Dermatology

Volumn 149, Issue 1, 2003, Pages 222-224

  Iwao, F ^a   Sawamura, D ^a   Yokota, K ^a   Shimizu, H ^a  

^a HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIALLERGIC AGENT; FEXOFENADINE; TRANILAST;

AGED; BLEPHARITIS; CASE REPORT; CONJUNCTIVAL HYPEREMIA; DRUG MECHANISM; ERYTHEMA; EYELID; GOOD GENERAL CONDITION; GRANULOMATOSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LABORATORY TEST; LETTER; MALE; PHYSICAL EXAMINATION; PRIORITY JOURNAL; SKIN BIOPSY; TREATMENT FAILURE; TREATMENT OUTCOME;

AGED; ANTHRANILIC ACIDS; ANTI-ALLERGIC AGENTS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLEPHARITIS; GRANULOMA; HUMANS; MALE; MELKERSSON-ROSENTHAL SYNDROME;

EID: 0042635549     PISSN: 00070963     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2133.2003.05428.x     Document Type: Letter

References (12)

1. Yeatts RP, White WL. Granulomatous blepharitis as a sign of Melkersson-Rosenthal syndrome. Ophthalmol 1997; 104: 1185-90.
2. Hornstein OP. Melkersson-Rosenthal syndrome: a neuromucocutaneous disease of complex origin. Curr Probl Dermatol 1973; 5: 117-56.
3. Adachi N, Hagiwara K, Akasaka T. A case of Melkersson-Rosenthal syndrome. Rinsho Derma 1995; 49: 901-3 [Japanese].
4. Chiba M, Kobayashi M, Shrohata T et al. Successful treatment of cheilitis granulomatosa with potent inhibitors of mediator release: possible involvement of mast cell in the pathogenesis. Jpn J Dermatol 1989; 99: 883-9 [Japanese].
5. Kato T, Tagami H. Successful treatment of cheilitis granulomatosa with tranilast. J Dermatol 1986; 13: 402-3.
6. Komatsu H, Kojima M, Tsutsumi N et al. Study of the mechanism of inhibitory action of tranilast on chemical mediator release. Jpn J Pharmacol 1988; 46: 43-51.
7. Yamada H, Tajima S, Nishikawa T et al. Tranilast, a selective inhibitor of collagen synthesis in human skin fibroblasts. J Biochem (Tokyo) 1994; 116: 892-7.
8. Fukuyama J, Ichikawa K, Hamano S et al. Tranilast suppresses the vascular intimal hyperplasia after balloon injury in rabbits fed on a high-cholesterol diet. Eur J Pharmacol 1996; 318: 327-32.
9. Mizuno K, Okamoto H, Horio T. Inhibitory influences of tranilast on multinucleated giant cell formation from monocytes by supernatant of concanavalin A-stimulated mononuclear cells. J Dermatol Sci 2000; 24: 166-70.
10. Kondo N, Fukutomi O, Shinbara M et al. Inhibition of interferon-gamma and interleukin-2 production from lymphocytes stimulated with food antigens by an anti-allergic drug, tranilast, in patients with food-sensitive atopic dermatitis. Biotherapy 1994; 8: 19-22.
11. Suga M, Yamasaki H, Nakagawa K et al. Mechanisms accounting for granulomatous responses in hypersensitivity pneumonitis. Sarcoidosis Vasc Diffuse Lung Dis 1997; 14: 131-8.
12. Fasis S, Burgio VL, Silvestri M et al. Multinucleated giant cell generation induced by interferon-gamma. Changes in the expression and distribution of the intercellular adhesion molecule-1 during macrophage fusion and multinucleated giant cell formation. Lab Invest 1994; 71: 737-44.