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Volumn 46, Issue 9, 1999, Pages 517-522

Pharmaco-Toxicological Mode of Action of Antimicrobial 5-Nitroimidazole Derivatives

(2)  Schmid, A a   Schmid, H b  

a NONE   (Germany)
b NONE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMALIA;

EID: 0042632836     PISSN: 0931184X     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1439-0442.1999.00245.x     Document Type: Article
Times cited : (8)

References (27)
  • 1
    • 0018059241 scopus 로고
    • Criteria for selecting chemical compounds for carcinogenicity resting: An essay
    • Acros, J. C., 1978: Criteria for selecting chemical compounds for carcinogenicity resting: An essay. J. Environ. Path. Toxicol. 1, 433-458.
    • (1978) J. Environ. Path. Toxicol. , vol.1 , pp. 433-458
    • Acros, J.C.1
  • 3
    • 0018098525 scopus 로고
    • Metabolism of 5-isopropyl-1-methyl-2-nitro-1H-imidazole. Identification of some urinary metabolites in the dog
    • Assandri, A., A. Perazzi, L. F. Zerilli, P. Ferrari, and E. Martinelli, 1978: Metabolism of 5-isopropyl-1-methyl-2-nitro-1H-imidazole. Identification of some urinary metabolites in the dog. Drug Metabol. Dispos. 6, 109-113.
    • (1978) Drug Metabol. Dispos. , vol.6 , pp. 109-113
    • Assandri, A.1    Perazzi, A.2    Zerilli, L.F.3    Ferrari, P.4    Martinelli, E.5
  • 4
    • 0017873260 scopus 로고
    • Pharmacokinetic and metabolic studies of the hypoxic cell radiosensitizer misonidazole
    • Flockhart, I. R., P. Large, D. Troup, S. L. Malcolm, and T. R. Marten, 1978: Pharmacokinetic and metabolic studies of the hypoxic cell radiosensitizer misonidazole. Xenobiotica 8, 97-105.
    • (1978) Xenobiotica , vol.8 , pp. 97-105
    • Flockhart, I.R.1    Large, P.2    Troup, D.3    Malcolm, S.L.4    Marten, T.R.5
  • 6
    • 0009303690 scopus 로고    scopus 로고
    • Introduction to Medicinal Chemistry
    • Wiley-VCH, New York and Weinheim
    • Gringauz, A., 1997: Introduction to Medicinal Chemistry. How Drugs Act and Why, (p. 275). Wiley-VCH, New York and Weinheim.
    • (1997) How Drugs Act and Why , pp. 275
    • Gringauz, A.1
  • 7
    • 0041687519 scopus 로고
    • Reductive metabolism of nitrogen-containing functional groups
    • Jakoby, W. B., J. R. Bend, and J. Caldwell (eds), Academic Press, New York
    • Hewick, D. S., 1982: Reductive metabolism of nitrogen-containing functional groups. In: Jakoby, W. B., J. R. Bend, and J. Caldwell (eds), Metabolic Basis of Detoxication, (pp. 151-170). Academic Press, New York.
    • (1982) Metabolic Basis of Detoxication , pp. 151-170
    • Hewick, D.S.1
  • 8
    • 0027156517 scopus 로고
    • Metronidazole and drug resistance
    • Johnson, P. J., 1993: Metronidazole and drug resistance. Parasitol. Today 9, 183-186.
    • (1993) Parasitol. Today , vol.9 , pp. 183-186
    • Johnson, P.J.1
  • 9
    • 0018603220 scopus 로고
    • Acetamide, a metabolite of metronidazole formed by the intestinal flora
    • Koch, R. L., E. J. T. Chrystal, B. B. Beaulieu, and P. Goldman, 1979: Acetamide, a metabolite of metronidazole formed by the intestinal flora. Biochem. Pharmacol. 28, 3611-3615.
    • (1979) Biochem. Pharmacol. , vol.28 , pp. 3611-3615
    • Koch, R.L.1    Chrystal, E.J.T.2    Beaulieu, B.B.3    Goldman, P.4
  • 10
    • 0019966166 scopus 로고
    • Drug residue formation from ronidazole, a 5-nitroimidazole. III. Studies on the mechanism of protein alkylation in vitro
    • Miwa, G. T., S. B. West, J. S. Walsh, F. J. Wolf, and A. Y. H. Lu, 1982: Drug residue formation from ronidazole, a 5-nitroimidazole. III. Studies on the mechanism of protein alkylation in vitro. Chem.-Biol. Interact. 41, 297-312.
    • (1982) Chem.-Biol. Interact. , vol.41 , pp. 297-312
    • Miwa, G.T.1    West, S.B.2    Walsh, J.S.3    Wolf, F.J.4    Lu, A.Y.H.5
  • 13
    • 0000106986 scopus 로고    scopus 로고
    • Biotransformation of xenobiotics
    • Klaassen, C. D., M. O. Amdur, and J. Doull (eds), McGraw-Hill, New York
    • Parkinson, A., 1996: Biotransformation of xenobiotics. In: Klaassen, C. D., M. O. Amdur, and J. Doull (eds), Casarett and Doull's Toxicology, 5th edn, (p. 120). McGraw-Hill, New York.
    • (1996) Casarett and Doull's Toxicology, 5th Edn , pp. 120
    • Parkinson, A.1
  • 14
    • 0018826389 scopus 로고
    • The reductive metabolism of metronidazole and ronidazole by aerobic liver microsomes
    • Perez-Reyes, E., B. Kalyanaraman, and R. P. Mason, 1980: The reductive metabolism of metronidazole and ronidazole by aerobic liver microsomes. Molecular Pharmacol. 17, 239-244.
    • (1980) Molecular Pharmacol. , vol.17 , pp. 239-244
    • Perez-Reyes, E.1    Kalyanaraman, B.2    Mason, R.P.3
  • 16
    • 0029045285 scopus 로고
    • Quantitative structure-activity relationships for antimicrobial nitroheterocyclic drugs
    • Rozenski, J., C. J. De Ranter, and H. Verplanken, 1995: Quantitative structure-activity relationships for antimicrobial nitroheterocyclic drugs. Quant. Struct.-Act. Relat. 14, 134-141.
    • (1995) Quant. Struct.-Act. Relat. , vol.14 , pp. 134-141
    • Rozenski, J.1    De Ranter, C.J.2    Verplanken, H.3
  • 17
    • 0015304363 scopus 로고
    • Induction of lung tumors and malignant lymphomas in mice by metronidazole
    • Rustia, M., and P. Shubik, 1972: Induction of lung tumors and malignant lymphomas in mice by metronidazole. J. Natl. Cancer Inst. 48, 721-729.
    • (1972) J. Natl. Cancer Inst. , vol.48 , pp. 721-729
    • Rustia, M.1    Shubik, P.2
  • 18
    • 0018736370 scopus 로고
    • Experimental induction of hepatomas, mammary tumors, and other tumors with metronidazole in noninbred Sas:MRC (W1) BR rats
    • Rustia, M., and P. Shubik, 1979: Experimental induction of hepatomas, mammary tumors, and other tumors with metronidazole in noninbred Sas:MRC (W1) BR rats. J. Natl. Cancer Inst. 63, 863-868.
    • (1979) J. Natl. Cancer Inst. , vol.63 , pp. 863-868
    • Rustia, M.1    Shubik, P.2
  • 19
    • 0022335619 scopus 로고
    • Toxikologische Beurteilung von Nitrofuranderivaten
    • Praxis.
    • Schmid, A., 1985: Toxikologische Beurteilung von Nitrofuranderivaten. Tierärztl. Praxis. 13, 471-477.
    • (1985) Tierärztl , vol.13 , pp. 471-477
    • Schmid, A.1
  • 21
    • 0019412990 scopus 로고
    • On the mutagenicity of nitroimidazoles
    • Voogd, C. E., 1981: On the mutagenicity of nitroimidazoles. Mutat. Res. 86, 243-277.
    • (1981) Mutat. Res. , vol.86 , pp. 243-277
    • Voogd, C.E.1
  • 22
    • 0019423923 scopus 로고
    • A major rat faecal metabolite of ipronidazole
    • Weiss, G., N. Rose, P. Duke, and T. H. Williams, 1981: A major rat faecal metabolite of ipronidazole. Xenobiotica 11, 207-215.
    • (1981) Xenobiotica , vol.11 , pp. 207-215
    • Weiss, G.1    Rose, N.2    Duke, P.3    Williams, T.H.4
  • 23
    • 0019944285 scopus 로고
    • Drug residue formation from ronidazole, a 5-nitroimidazole. I. Characterization of in vitro protein alkylation
    • West, S. B., P. G. Wislocki, K. M. Fiorentini, R. Alvaro, F. J. Wolf, and A. Y. H. Lu, 1982a: Drug residue formation from ronidazole, a 5-nitroimidazole. I. Characterization of in vitro protein alkylation. Chem.-Biol. Interact. 41, 265-279.
    • (1982) Chem.-Biol. Interact. , vol.41 , pp. 265-279
    • West, S.B.1    Wislocki, P.G.2    Fiorentini, K.M.3    Alvaro, R.4    Wolf, F.J.5    Lu, A.Y.H.6
  • 24
    • 0019943532 scopus 로고
    • Drug residue formation from ronidazole, a 5-nitroimidazole. II. Involvement of microsomal NADPH-cytochrome P-450 reductase in protein alkylation in vitro
    • West, S. B., P. G. Wislocki, F. J. Wolf, and A. Y. H. Lu, 1982b: Drug residue formation from ronidazole, a 5-nitroimidazole. II. Involvement of microsomal NADPH-cytochrome P-450 reductase in protein alkylation in vitro. Chem.-Biol. Interact. 41, 281-296.
    • (1982) Chem.-Biol. Interact. , vol.41 , pp. 281-296
    • West, S.B.1    Wislocki, P.G.2    Wolf, F.J.3    Lu, A.Y.H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.