Increased in vitro cellular drug resistance is related to poor outcome in high-risk childhood acute lymphoblastic leukaemia

British Journal of Haematology

Volumn 122, Issue 3, 2003, Pages 376-385

  Frost, Britt Marie ^a   Nygren, Peter ^b   Gustafsson, Göran ^c   Forestier, Erik ^d   Jonsson, Olafur G ^e   Kanerva, Jukka ^f   Nygaard, Randi ^g   Schmiegelow, Kjeld ^h   Larsson, Rolf ^b   Lönnerholm, Gudmar ^a  

^a UNIVERSITY CHILDREN S HOSPITAL   (Sweden)

^b UPPSALA UNIVERSITY HOSPITAL   (Sweden)

^c KAROLINSKA INSTITUTE   (Sweden)

^d UMEÅ UNIVERSITY   (Sweden)

^e Department of Paediatrics ^*  (Iceland)

^f UNIVERSITY OF HELSINKI   (Finland)

^g TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

^h Rigshospitalet   (Denmark)

Author keywords

Acute lymphoblastic leukaemia; Childhood; Cytotoxicity; Drug resistance; In vitro assay

Indexed keywords

4 HYDROPEROXYCYCLOPHOSPHAMIDE; AMSACRINE; ANTINEOPLASTIC AGENT; ASPARAGINASE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; ETOPOSIDE; METHOTREXATE; PREDNISOLONE; TIOGUANINE; VINCRISTINE;

ACUTE LYMPHOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; CANCER RECURRENCE; CANCER RESISTANCE; CANCER RISK; CANCER SURVIVAL; CHILD; CHILDHOOD LEUKEMIA; CONTROLLED STUDY; CYTOFLUOROMETRY; CYTOTOXICITY; DISEASE SEVERITY; DRUG ACTIVITY; FEMALE; FOLLOW UP; HIGH RISK POPULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; TREATMENT OUTCOME;

ADOLESCENT; AMSACRINE; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; CHILD; CHILD, PRESCHOOL; CYTOTOXICITY TESTS, IMMUNOLOGIC; DEXAMETHASONE; DISEASE-FREE SURVIVAL; DOXORUBICIN; DRUG RESISTANCE, NEOPLASM; FLUOROMETRY; FOLLOW-UP STUDIES; HUMANS; INFANT; LEUKEMIA, LYMPHOCYTIC, ACUTE, L1; LEUKOCYTE COUNT; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RISK ASSESSMENT; STATISTICS, NONPARAMETRIC;

EID: 0042629669     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.2003.04442.x     Document Type: Article

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